ID   THIO_CHLTI              Reviewed;         108 AA.
AC   P10472;
DT   01-JUL-1989, integrated into UniProtKB/Swiss-Prot.
DT   21-AUG-2007, sequence version 5.
DT   25-MAY-2022, entry version 100.
DE   RecName: Full=Thioredoxin;
DE            Short=Trx;
GN   Name=trxA;
OS   Chlorobaculum thiosulfatiphilum (Chlorobium limicola f.sp.
OS   thiosulfatophilum).
OC   Bacteria; Chlorobi; Chlorobia; Chlorobiales; Chlorobiaceae; Chlorobaculum.
OX   NCBI_TaxID=115852;
RN   [1]
RP   PROTEIN SEQUENCE, AND IDENTIFICATION BY MASS SPECTROMETRY.
RX   PubMed=3294835; DOI=10.1016/s0021-9258(18)47599-0;
RA   Mathews W.R., Johnson R.S., Cornwell K.L., Johnson T.C., Buchanan B.B.,
RA   Biemann K.;
RT   "Mass spectrometrically derived amino acid sequence of thioredoxin from
RT   Chlorobium, an evolutionarily prominent photosynthetic bacterium.";
RL   J. Biol. Chem. 262:7537-7545(1987).
RN   [2]
RP   PROTEIN SEQUENCE, AND IDENTIFICATION BY MASS SPECTROMETRY.
RA   Biemann K., Papayannopoulos I.A.;
RT   "Amino acid sequencing of proteins.";
RL   Acc. Chem. Res. 27:370-378(1994).
CC   -!- FUNCTION: Participates in various redox reactions through the
CC       reversible oxidation of its active center dithiol to a disulfide and
CC       catalyzes dithiol-disulfide exchange reactions.
CC   -!- SIMILARITY: Belongs to the thioredoxin family. {ECO:0000305}.
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DR   AlphaFoldDB; P10472; -.
DR   SMR; P10472; -.
DR   GO; GO:0015035; F:protein-disulfide reductase activity; IEA:InterPro.
DR   InterPro; IPR005746; Thioredoxin.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   InterPro; IPR017937; Thioredoxin_CS.
DR   InterPro; IPR013766; Thioredoxin_domain.
DR   Pfam; PF00085; Thioredoxin; 1.
DR   PIRSF; PIRSF000077; Thioredoxin; 1.
DR   SUPFAM; SSF52833; SSF52833; 1.
DR   TIGRFAMs; TIGR01068; thioredoxin; 1.
DR   PROSITE; PS00194; THIOREDOXIN_1; 1.
DR   PROSITE; PS51352; THIOREDOXIN_2; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Disulfide bond; Electron transport;
KW   Redox-active center; Transport.
FT   CHAIN           1..108
FT                   /note="Thioredoxin"
FT                   /id="PRO_0000120087"
FT   DOMAIN          2..108
FT                   /note="Thioredoxin"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00691"
FT   DISULFID        32..35
FT                   /note="Redox-active"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00691"
FT   UNSURE          24
FT                   /note="L or I"
FT   UNSURE          38
FT                   /note="L or I"
FT   UNSURE          58
FT                   /note="L or I"
FT   UNSURE          72
FT                   /note="I or L"
FT   UNSURE          81
FT                   /note="I or L"
SQ   SEQUENCE   108 AA;  11828 MW;  168E1811637F24D4 CRC64;
     AGKYFEATDK NFQTEILDSD KAVLVDFWAS WCGPCMMLGP VIEQLADDYE GKAIIAKLNV
     DENPNIAGQY GIRSIPTMLI IKGGKVVDQM VGALPKNMIA KKIDEHIG