ID   THIO_KITAU              Reviewed;         106 AA.
AC   P33791;
DT   01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1994, sequence version 1.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=Thioredoxin;
DE            Short=Trx;
DE   Flags: Fragment;
GN   Name=trxA;
OS   Kitasatospora aureofaciens (Streptomyces aureofaciens).
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Kitasatospora.
OX   NCBI_TaxID=1894;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=BMK;
RX   PubMed=8125314; DOI=10.1016/0378-1119(94)90822-2;
RA   Labudova O., Nemethova M., Turna J., Kollarova M.;
RT   "PCR cloning and sequencing of the coding portion of the thioredoxin-
RT   encoding gene from Streptomyces aureofaciens BMK.";
RL   Gene 138:263-264(1994).
CC   -!- FUNCTION: Participates in various redox reactions through the
CC       reversible oxidation of its active center dithiol to a disulfide and
CC       catalyzes dithiol-disulfide exchange reactions.
CC   -!- SIMILARITY: Belongs to the thioredoxin family. {ECO:0000305}.
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DR   EMBL; X72799; CAA51317.1; -; Genomic_DNA.
DR   PIR; S33357; S33357.
DR   AlphaFoldDB; P33791; -.
DR   SMR; P33791; -.
DR   GO; GO:0015035; F:protein-disulfide reductase activity; IEA:InterPro.
DR   InterPro; IPR005746; Thioredoxin.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   InterPro; IPR017937; Thioredoxin_CS.
DR   InterPro; IPR013766; Thioredoxin_domain.
DR   Pfam; PF00085; Thioredoxin; 1.
DR   PIRSF; PIRSF000077; Thioredoxin; 1.
DR   SUPFAM; SSF52833; SSF52833; 1.
DR   TIGRFAMs; TIGR01068; thioredoxin; 1.
DR   PROSITE; PS00194; THIOREDOXIN_1; 1.
DR   PROSITE; PS51352; THIOREDOXIN_2; 1.
PE   3: Inferred from homology;
KW   Disulfide bond; Electron transport; Redox-active center; Transport.
FT   CHAIN           <1..106
FT                   /note="Thioredoxin"
FT                   /id="PRO_0000120134"
FT   DOMAIN          <1..106
FT                   /note="Thioredoxin"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00691"
FT   DISULFID        31..34
FT                   /note="Redox-active"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00691"
FT   NON_TER         1
SQ   SEQUENCE   106 AA;  11307 MW;  7B905E1C85AFB234 CRC64;
     GATVKVTNAT FKSDVLESDK PVLVHFEGPW CGPCKMVAPV LDEIANEYEG KVKVAKVNTD
     ENPQLASQYG VRSIPTRLMF KGGEVAANMV GAAPKTRLAA FLDASL