ID   BRRF1_EBVG              Reviewed;         310 AA.
AC   P0C722; Q777E3;
DT   01-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-SEP-2009, sequence version 1.
DT   02-JUN-2021, entry version 27.
DE   RecName: Full=Transcriptional activator BRRF1;
GN   ORFNames=BRRF1;
OS   Epstein-Barr virus (strain GD1) (HHV-4) (Human herpesvirus 4).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Gammaherpesvirinae; Lymphocryptovirus.
OX   NCBI_TaxID=10376;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16306603; DOI=10.1128/jvi.79.24.15323-15330.2005;
RA   Zeng M.-S., Li D.-J., Liu Q.-L., Song L.-B., Li M.-Z., Zhang R.-H.,
RA   Yu X.-J., Wang H.-M., Ernberg I., Zeng Y.-X.;
RT   "Genomic sequence analysis of Epstein-Barr virus strain GD1 from a
RT   nasopharyngeal carcinoma patient.";
RL   J. Virol. 79:15323-15330(2005).
CC   -!- FUNCTION: Enhances the ability of BRLF1 to induce lytic infection by
CC       cooperating with it to transcriptionally activate the BZLF1 promoter.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the lymphocryptovirus BBRF1 family.
CC       {ECO:0000305}.
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DR   EMBL; AY961628; AAY41123.1; -; Genomic_DNA.
DR   RefSeq; YP_401675.1; NC_007605.1.
DR   SMR; P0C722; -.
DR   BioGRID; 971770; 2.
DR   IntAct; P0C722; 11.
DR   DNASU; 3783728; -.
DR   GeneID; 3783728; -.
DR   KEGG; vg:3783728; -.
DR   Proteomes; UP000007641; Genome.
DR   InterPro; IPR006878; Herpes_BBRF1.
DR   Pfam; PF04793; Herpes_BBRF1; 1.
PE   3: Inferred from homology;
KW   Early protein; Transcription; Transcription regulation.
FT   CHAIN           1..310
FT                   /note="Transcriptional activator BRRF1"
FT                   /id="PRO_0000382440"
SQ   SEQUENCE   310 AA;  35319 MW;  05F8A4719F604D03 CRC64;
     MASSNRGNAR PLKSFLHELY LKHYPEVGDV VHLLNTIGVD CDLPPSHPLL TAQRGLFLAR
     VLQAVQQHKL LEDTIVPKIL KKLAYFLELL SYYSPKDEQR DIAEVLDHLK TNRDLGLDDR
     LWALIRKLRQ DRHHASVNVL MPGSDYTAVS LQYYDGISIG MRKVIADVCR SGYASMPSMT
     ATHNLSHQLL MASGPSEEPC AWRGFFNQVL LWTVALCKFR RCIYYNYIQG SIATISQLLH
     LEIKALCSWI ISQDGMRLFQ HSRPLLTLWE SVAANQEVTD AITLPDCAEY IDLLKHTKHV
     LENCSAMQYK