ID   BRRF2_EBVB9             Reviewed;         537 AA.
AC   P03210; Q777E2;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   02-JUN-2021, entry version 64.
DE   RecName: Full=Tegument protein BRRF2;
GN   ORFNames=BRRF2;
OS   Epstein-Barr virus (strain B95-8) (HHV-4) (Human herpesvirus 4).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Gammaherpesvirinae; Lymphocryptovirus.
OX   NCBI_TaxID=10377;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=6087149; DOI=10.1038/310207a0;
RA   Baer R., Bankier A.T., Biggin M.D., Deininger P.L., Farrell P.J.,
RA   Gibson T.J., Hatfull G., Hudson G.S., Satchwell S.C., Seguin C.,
RA   Tuffnell P.S., Barrell B.G.;
RT   "DNA sequence and expression of the B95-8 Epstein-Barr virus genome.";
RL   Nature 310:207-211(1984).
RN   [2]
RP   SUBCELLULAR LOCATION.
RX   PubMed=15534216; DOI=10.1073/pnas.0407320101;
RA   Johannsen E., Luftig M., Chase M.R., Weicksel S., Cahir-McFarland E.,
RA   Illanes D., Sarracino D., Kieff E.;
RT   "Proteins of purified Epstein-Barr virus.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:16286-16291(2004).
CC   -!- SUBCELLULAR LOCATION: Virion tegument {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the lymphocryptovirus BRRF2 family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; V01555; CAA24815.1; -; Genomic_DNA.
DR   EMBL; AJ507799; CAD53426.1; -; Genomic_DNA.
DR   PIR; B43043; QQBE30.
DR   RefSeq; YP_401676.1; NC_007605.1.
DR   PRIDE; P03210; -.
DR   DNASU; 3783729; -.
DR   GeneID; 3783729; -.
DR   KEGG; vg:3783729; -.
DR   Proteomes; UP000153037; Genome.
DR   GO; GO:0019033; C:viral tegument; IEA:UniProtKB-SubCell.
DR   InterPro; IPR008550; Herpesvirus_BRRF2-like.
DR   Pfam; PF05734; DUF832; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Virion; Virion tegument.
FT   CHAIN           1..537
FT                   /note="Tegument protein BRRF2"
FT                   /id="PRO_0000116260"
FT   REGION          321..366
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          378..398
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          414..466
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          486..537
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        331..357
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        414..436
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        450..466
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        493..512
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   537 AA;  56955 MW;  01059F793C6074E0 CRC64;
     MSGQQRGSVI LVPEHLAGAL TKLMSDFITG QDVTLSGGNI AVKIRDAINQ TPGGGDVAIL
     SSLFALWNAL PTSGRQSSRD DLIPAAVQAL TTAHNLCLGV IPGETSHKDT PESLLRAIVT
     GLQKLWVDSC GCPECLQCLK GLKAIKPGLY EIPRIIPHTK QCSPVNLLNM LVHKLVALRG
     HVQLAYDARV LTPDFHEIPD LDDSDAVFAR TLLAALFHLN MFFILKDYIT QDSMSLKQAL
     SGHWMSATGN PLPAAPETLR DYLEAFRNSD NHFYLPTTGP LNTFQFPEEL LGRVVVIDSS
     LCAASHVQDV ITHGVGAGVP RPRFSALPPA PSREPQQTCS QLTSRGNESS RRNLGQPGGT
     SPAVPPVCPI VSLTASGAKQ NRGGMGSLHL AKPEETSPAV SPVCPIASPA ASRSKQHCGV
     TGSSQAAPSF SSVAPVASLS GDLEEEEEGS RESPSLPSSK KGDEEFEAWL EAQDANLEDV
     QREFSGLRVI GDEDEDGSED GEFSDLDLSD SDHEGDEGGG AVGGGRSLHS LYSLSVV