THLP1_ARATH
ID THLP1_ARATH Reviewed; 260 AA.
AC A0A1P8B554; O22973; Q9STX6;
DT 25-OCT-2017, integrated into UniProtKB/Swiss-Prot.
DT 12-APR-2017, sequence version 1.
DT 25-MAY-2022, entry version 27.
DE RecName: Full=Thaumatin-like protein 1 {ECO:0000303|PubMed:15988566};
DE Short=AtTLP1 {ECO:0000303|PubMed:15988566};
DE Flags: Precursor;
GN Name=TLP1 {ECO:0000303|PubMed:15988566};
GN OrderedLocusNames=At4g24180 {ECO:0000312|EMBL:ANM66723.1};
GN ORFNames=T19F6.2 {ECO:0000312|EMBL:AAB63607.1},
GN T22A6.10 {ECO:0000312|EMBL:CAB45053.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-204 (ISOFORM 1).
RC STRAIN=cv. Wassilewskija;
RX PubMed=12799357; DOI=10.1101/gr.728603;
RA Schmid K.J., Soerensen T.R., Stracke R., Torjek O., Altmann T.,
RA Mitchell-Olds T., Weisshaar B.;
RT "Large-scale identification and analysis of genome-wide single-nucleotide
RT polymorphisms for mapping in Arabidopsis thaliana.";
RL Genome Res. 13:1250-1257(2003).
RN [4]
RP FUNCTION, DISRUPTION PHENOTYPE, INDUCTION BY ETHYLENE; PSEUDOMONAS
RP FLUORESCENS AND PSEUDOMONAS PUTIDA, AND TISSUE SPECIFICITY.
RC STRAIN=cv. Landsberg erecta;
RX PubMed=15988566; DOI=10.1007/s11103-005-3097-y;
RA Leon-Kloosterziel K.M., Verhagen B.W.M., Keurentjes J.J.B., VanPelt J.A.,
RA Rep M., VanLoon L.C., Pieterse C.M.J.;
RT "Colonization of the Arabidopsis rhizosphere by fluorescent Pseudomonas
RT spp. activates a root-specific, ethylene-responsive PR-5 gene in the
RT vascular bundle.";
RL Plant Mol. Biol. 57:731-748(2005).
CC -!- FUNCTION: Involved in local responses of roots to colonization by non-
CC pathogenic plant growth-promoting rhizobacteria (PGPR) fluorescent
CC Pseudomonas spp., but seems to not being required for the establishment
CC of subsequent induced systemic resistance (ISR).
CC {ECO:0000269|PubMed:15988566}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=A0A1P8B554-1; Sequence=Displayed;
CC Name=2;
CC IsoId=A0A1P8B554-2; Sequence=VSP_059133;
CC -!- TISSUE SPECIFICITY: Expressed only in roots.
CC {ECO:0000269|PubMed:15988566}.
CC -!- INDUCTION: Accumulates locally in the root vascular bundle upon
CC P.fluorescens WCS417r and P.putida WCS358r bacteria root colonization
CC prior to induced systemic resistance (ISR) and after ethylene treatment
CC (e.g. ACC). {ECO:0000269|PubMed:15988566}.
CC -!- DISRUPTION PHENOTYPE: Normal induced systemic resistance (ISR) mediated
CC by P.fluorescens WCS417r toward the pathogenic bacteria P.syringae pv.
CC tomato DC3000. {ECO:0000269|PubMed:15988566}.
CC -!- SIMILARITY: Belongs to the thaumatin family. {ECO:0000255|PROSITE-
CC ProRule:PRU00699}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAB63607.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC002343; AAB63607.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AL078637; CAB45053.1; -; Genomic_DNA.
DR EMBL; AL161561; CAB79328.1; -; Genomic_DNA.
DR EMBL; CP002687; ANM66720.1; -; Genomic_DNA.
DR EMBL; CP002687; ANM66723.1; -; Genomic_DNA.
DR EMBL; CF652807; -; NOT_ANNOTATED_CDS; mRNA.
DR PIR; T09881; T09881.
DR RefSeq; NP_001328599.1; NM_001341652.1. [A0A1P8B554-2]
DR RefSeq; NP_194149.2; NM_118551.3. [A0A1P8B554-1]
DR AlphaFoldDB; A0A1P8B554; -.
DR SMR; A0A1P8B554; -.
DR STRING; 3702.AT4G24180.1; -.
DR EnsemblPlants; AT4G24180.5; AT4G24180.5; AT4G24180. [A0A1P8B554-2]
DR EnsemblPlants; AT4G24180.6; AT4G24180.6; AT4G24180. [A0A1P8B554-1]
DR GeneID; 828519; -.
DR Gramene; AT4G24180.5; AT4G24180.5; AT4G24180. [A0A1P8B554-2]
DR Gramene; AT4G24180.6; AT4G24180.6; AT4G24180. [A0A1P8B554-1]
DR KEGG; ath:AT4G24180; -.
DR Araport; AT4G24180; -.
DR eggNOG; ENOG502QPIR; Eukaryota.
DR OMA; PWFPNFF; -.
DR PRO; PR:A0A1P8B554; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; A0A1P8B554; baseline and differential.
DR GO; GO:0006952; P:defense response; IBA:GO_Central.
DR GO; GO:0009617; P:response to bacterium; IEP:UniProtKB.
DR GO; GO:0009723; P:response to ethylene; IEP:UniProtKB.
DR Gene3D; 2.60.110.10; -; 1.
DR InterPro; IPR037176; Osmotin/thaumatin-like_sf.
DR InterPro; IPR001938; Thaumatin.
DR PANTHER; PTHR31048; PTHR31048; 1.
DR Pfam; PF00314; Thaumatin; 1.
DR PIRSF; PIRSF002703; Thaumatin; 1.
DR PRINTS; PR00347; THAUMATIN.
DR SMART; SM00205; THN; 1.
DR SUPFAM; SSF49870; SSF49870; 1.
DR PROSITE; PS51367; THAUMATIN_2; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Disulfide bond; Pathogenesis-related protein;
KW Plant defense; Reference proteome; Signal.
FT SIGNAL 1..32
FT /evidence="ECO:0000255"
FT CHAIN 33..260
FT /note="Thaumatin-like protein 1"
FT /evidence="ECO:0000255"
FT /id="PRO_0000441918"
FT DISULFID 41..255
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00699"
FT DISULFID 89..100
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00699"
FT DISULFID 105..112
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00699"
FT DISULFID 166..245
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00699"
FT DISULFID 171..228
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00699"
FT DISULFID 179..191
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00699"
FT DISULFID 195..204
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00699"
FT DISULFID 205..215
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00699"
FT VAR_SEQ 24..28
FT /note="Missing (in isoform 2)"
FT /id="VSP_059133"
FT CONFLICT 5
FT /note="V -> A (in Ref. 3; CF652807)"
FT /evidence="ECO:0000305"
FT CONFLICT 28..30
FT /note="VGS -> EGR (in Ref. 3; CF652807)"
FT /evidence="ECO:0000305"
FT CONFLICT 38
FT /note="V -> E (in Ref. 3; CF652807)"
FT /evidence="ECO:0000305"
FT CONFLICT 45..46
FT /note="VW -> GG (in Ref. 3; CF652807)"
FT /evidence="ECO:0000305"
FT CONFLICT 64
FT /note="E -> K (in Ref. 3; CF652807)"
FT /evidence="ECO:0000305"
FT CONFLICT 86
FT /note="R -> Q (in Ref. 3; CF652807)"
FT /evidence="ECO:0000305"
FT CONFLICT 94
FT /note="D -> N (in Ref. 3; CF652807)"
FT /evidence="ECO:0000305"
FT CONFLICT 111
FT /note="E -> K (in Ref. 3; CF652807)"
FT /evidence="ECO:0000305"
FT CONFLICT 125
FT /note="E -> K (in Ref. 3; CF652807)"
FT /evidence="ECO:0000305"
FT CONFLICT 134
FT /note="D -> N (in Ref. 3; CF652807)"
FT /evidence="ECO:0000305"
FT CONFLICT 140..147
FT /note="DFYDVSLV -> NFYNVSLG (in Ref. 3; CF652807)"
FT /evidence="ECO:0000305"
FT CONFLICT 156..163
FT /note="VEASGGSE -> GEARGGSK (in Ref. 3; CF652807)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 260 AA; 27451 MW; 13A01AEA92AD03B5 CRC64;
MIITVLHSHV SFYFIILSFL FFHALHLVGS DGATITIVNR CSFTVWPGIL SNSGSGDIGT
TGFELVPGGS RSFQAPASWS GRFWARTGCN FNSDTGQGTC LTGDCGSNQV ECNGAGAKPP
ATLAEFTIGS GPADPARKQD FYDVSLVDGY NVPMLVEASG GSEGTCLTTG CVTDLNQKCP
TELRFGSGSA CKSACEAFGS PEYCCSGAYA SPTECKPSMY SEIFKSACPR SYSYAFDDAT
STFTCTDADY TITFCPSLPR
