ID   THN1_VISAL              Reviewed;          46 AA.
AC   P01537;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   10-FEB-2021, entry version 77.
DE   RecName: Full=Viscotoxin-1-PS;
GN   Name=THI2.4;
OS   Viscum album (European mistletoe).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   Santalales; Viscaceae; Viscum.
OX   NCBI_TaxID=3972;
RN   [1]
RP   PROTEIN SEQUENCE.
RC   STRAIN=Subsp. austriacum;
RX   PubMed=4417993;
RA   Samuelsson G., Jayawardene A.L.;
RT   "Isolation and characterization of viscotoxin 1-Ps from Viscum album L.
RT   ssp. austriacum (Wiesb.) vollmann, growing on Pinus silvestris.";
RL   Acta Pharm. Suec. 11:175-184(1974).
CC   -!- FUNCTION: Thionins are small plant proteins which are toxic to animal
CC       cells. They seem to exert their toxic effect at the level of the cell
CC       membrane. Their precise function is not known.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the plant thionin (TC 1.C.44) family.
CC       {ECO:0000305}.
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DR   PIR; A01800; VTVA1P.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR   GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.1350.10; -; 1.
DR   InterPro; IPR001010; Thionin.
DR   InterPro; IPR036391; Thionin-like_sf.
DR   Pfam; PF00321; Thionin; 1.
DR   PRINTS; PR00287; THIONIN.
DR   SUPFAM; SSF57429; SSF57429; 1.
DR   PROSITE; PS00271; THIONIN; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Disulfide bond; Plant defense; Secreted; Toxin.
FT   CHAIN           1..46
FT                   /note="Viscotoxin-1-PS"
FT                   /id="PRO_0000221482"
FT   DISULFID        3..40
FT                   /evidence="ECO:0000250"
FT   DISULFID        4..32
FT                   /evidence="ECO:0000250"
FT   DISULFID        16..26
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   46 AA;  4904 MW;  CA2C06DB6A80A689 CRC64;
     KSCCPBTTGR BIYBTCRFGG GSRZVCARIS GCKIISASTC PSYPBK