ID   THN7_HORVU              Reviewed;         137 AA.
AC   Q42838;
DT   01-MAR-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 74.
DE   RecName: Full=Thionin BTH7;
DE   Contains:
DE     RecName: Full=Thionin BTH7;
DE   Contains:
DE     RecName: Full=Acidic protein;
DE   Flags: Precursor;
OS   Hordeum vulgare (Barley).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC   Pooideae; Triticodae; Triticeae; Hordeinae; Hordeum.
OX   NCBI_TaxID=4513;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Holtorf S., Schuetz C., Apel K., Bohlmann H.;
RT   "Specific and distinct expression patterns of two members of the thionin
RT   multigene family of barley in transgenic tobacco.";
RL   Submitted (MAR-1996) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Thionins are small plant proteins which are toxic to animal
CC       cells. They seem to exert their toxic effect at the level of the cell
CC       membrane. Their precise function is not known.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the plant thionin (TC 1.C.44) family.
CC       {ECO:0000305}.
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DR   EMBL; L36883; AAA91048.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q42838; -.
DR   SMR; Q42838; -.
DR   ExpressionAtlas; Q42838; baseline.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR   GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.1350.10; -; 1.
DR   InterPro; IPR001010; Thionin.
DR   InterPro; IPR036391; Thionin-like_sf.
DR   PANTHER; PTHR33920; PTHR33920; 1.
DR   Pfam; PF00321; Thionin; 1.
DR   PRINTS; PR00287; THIONIN.
DR   SUPFAM; SSF57429; SSF57429; 1.
DR   PROSITE; PS00271; THIONIN; 1.
PE   2: Evidence at transcript level;
KW   Disulfide bond; Plant defense; Secreted; Signal; Toxin.
FT   SIGNAL          1..28
FT                   /evidence="ECO:0000255"
FT   CHAIN           29..74
FT                   /note="Thionin BTH7"
FT                   /id="PRO_0000034122"
FT   CHAIN           75..137
FT                   /note="Acidic protein"
FT                   /id="PRO_0000034123"
FT   DISULFID        31..68
FT                   /evidence="ECO:0000250"
FT   DISULFID        32..60
FT                   /evidence="ECO:0000250"
FT   DISULFID        40..58
FT                   /evidence="ECO:0000250"
FT   DISULFID        44..54
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   137 AA;  14676 MW;  7BDBAF7082F205BE CRC64;
     MATNKSIKSV VICVLILGLV LEQVQVEGKS CCKNTTGRNC YNACRFAGGS RPVCATACGC
     KIISGPTCPR DYPKLNLLPE SGEPNVTEYC TIGCRTSVCD NMDNVSRGQE MKFDMGLCSN
     ACARFCNDGE VIQSVEA