ID   THN_PYRPU               Reviewed;          47 AA.
AC   P07504;
DT   01-APR-1988, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1988, sequence version 1.
DT   25-MAY-2022, entry version 86.
DE   RecName: Full=Thionin;
GN   Name=THI1;
OS   Pyrularia pubera (Buffalo nut) (Oil nut).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   Santalales; Cervantesiaceae; Pyrularia.
OX   NCBI_TaxID=3960;
RN   [1]
RP   PROTEIN SEQUENCE.
RX   PubMed=3985614; DOI=10.1016/0003-9861(85)90136-5;
RA   Vernon L.P., Evett G.E., Zeikus R.D., Gray W.R.;
RT   "A toxic thionin from Pyrularia pubera: purification, properties, and amino
RT   acid sequence.";
RL   Arch. Biochem. Biophys. 238:18-29(1985).
CC   -!- FUNCTION: Thionins are small plant proteins which are toxic to animal
CC       cells. They seem to exert their toxic effect at the level of the cell
CC       membrane. Their precise function is not known.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the plant thionin (TC 1.C.44) family.
CC       {ECO:0000305}.
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DR   PIR; A24074; A24074.
DR   AlphaFoldDB; P07504; -.
DR   SMR; P07504; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR   GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.1350.10; -; 1.
DR   InterPro; IPR001010; Thionin.
DR   InterPro; IPR036391; Thionin-like_sf.
DR   Pfam; PF00321; Thionin; 1.
DR   PRINTS; PR00287; THIONIN.
DR   SUPFAM; SSF57429; SSF57429; 1.
DR   PROSITE; PS00271; THIONIN; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Disulfide bond; Plant defense; Secreted; Toxin.
FT   CHAIN           1..47
FT                   /note="Thionin"
FT                   /id="PRO_0000221481"
FT   DISULFID        3..41
FT                   /evidence="ECO:0000250"
FT   DISULFID        4..31
FT                   /evidence="ECO:0000250"
FT   DISULFID        16..27
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   47 AA;  5288 MW;  87E10460D8E4C6E1 CRC64;
     KSCCRNTWAR NCYNVCRLPG TISREICAKK CDCKIISGTT CPSDYPK