BRTL2_ARATH
ID BRTL2_ARATH Reviewed; 418 AA.
AC Q9C9R4; Q67ZI8;
DT 09-JAN-2013, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 120.
DE RecName: Full=Probable mitochondrial adenine nucleotide transporter BTL2;
DE AltName: Full=Adenine nucleotide transporter BT1-like protein 2;
GN OrderedLocusNames=At1g78180; ORFNames=T11I11.120;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP GENE FAMILY.
RX PubMed=15003237; DOI=10.1016/j.tplants.2004.01.007;
RA Picault N., Hodges M., Palmieri L., Palmieri F.;
RT "The growing family of mitochondrial carriers in Arabidopsis.";
RL Trends Plant Sci. 9:138-146(2004).
CC -!- FUNCTION: Probable mitochondrial adenylate carrier that catalyzes the
CC transport of ATP, ADP and AMP. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC Multi-pass membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the mitochondrial carrier (TC 2.A.29) family.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAD43860.1; Type=Miscellaneous discrepancy; Note=Sequencing errors.; Evidence={ECO:0000305};
CC Sequence=BAD43892.1; Type=Miscellaneous discrepancy; Note=Sequencing errors.; Evidence={ECO:0000305};
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DR EMBL; AC012680; AAG52097.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE36078.1; -; Genomic_DNA.
DR EMBL; AK176097; BAD43860.1; ALT_SEQ; mRNA.
DR EMBL; AK176129; BAD43892.1; ALT_SEQ; mRNA.
DR PIR; B96811; B96811.
DR RefSeq; NP_565171.4; NM_106468.4.
DR AlphaFoldDB; Q9C9R4; -.
DR SMR; Q9C9R4; -.
DR STRING; 3702.AT1G78180.1; -.
DR PaxDb; Q9C9R4; -.
DR PRIDE; Q9C9R4; -.
DR ProteomicsDB; 240707; -.
DR EnsemblPlants; AT1G78180.1; AT1G78180.1; AT1G78180.
DR GeneID; 844154; -.
DR Gramene; AT1G78180.1; AT1G78180.1; AT1G78180.
DR KEGG; ath:AT1G78180; -.
DR Araport; AT1G78180; -.
DR TAIR; locus:2194714; AT1G78180.
DR eggNOG; KOG0752; Eukaryota.
DR eggNOG; KOG0764; Eukaryota.
DR HOGENOM; CLU_015166_10_4_1; -.
DR InParanoid; Q9C9R4; -.
DR OMA; LAMGFNI; -.
DR OrthoDB; 1253450at2759; -.
DR PhylomeDB; Q9C9R4; -.
DR PRO; PR:Q9C9R4; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9C9R4; baseline and differential.
DR Genevisible; Q9C9R4; AT.
DR GO; GO:0009941; C:chloroplast envelope; HDA:TAIR.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 1.50.40.10; -; 1.
DR InterPro; IPR002067; Mit_carrier.
DR InterPro; IPR018108; Mitochondrial_sb/sol_carrier.
DR InterPro; IPR023395; Mt_carrier_dom_sf.
DR Pfam; PF00153; Mito_carr; 3.
DR PRINTS; PR00926; MITOCARRIER.
DR SUPFAM; SSF103506; SSF103506; 1.
DR PROSITE; PS50920; SOLCAR; 3.
PE 2: Evidence at transcript level;
KW Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome;
KW Repeat; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..418
FT /note="Probable mitochondrial adenine nucleotide
FT transporter BTL2"
FT /id="PRO_0000420804"
FT TRANSMEM 127..147
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TRANSMEM 180..200
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TRANSMEM 221..241
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TRANSMEM 276..296
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TRANSMEM 335..355
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TRANSMEM 383..403
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT REPEAT 122..205
FT /note="Solcar 1"
FT REPEAT 215..300
FT /note="Solcar 2"
FT REPEAT 329..414
FT /note="Solcar 3"
SQ SEQUENCE 418 AA; 45822 MW; 09D3E6E61B06959B CRC64;
MSGLDIYPHD PSSSSSTSSI DLSNEAFFST GGLFLEPPGV SSSFFDSISS KCSDSEPLHF
PGYWRNKTRL RSGKNFMFLS VSLSKDRSEQ QCKKALAQND EIPGKDNRKR SVIGGVRRRG
TMNTRKHLWA GAVAAMVSKT FLAPLERLKL EYTVRGEQRN LLVVAKSIAT TQGLTGFWKG
NLLNVLRTAP FKAVNFCAYD TYRKQLLKIA GNQEATNFER FVAGAAAGIT ATVLCLPLDT
IRTKLVARGG EALGGIGGAF RYMIQTEGLF SLYKGLVPSI ASMALSGAVF YGVYDILKSS
FLHTPEGRKR LIDMKQQGQE LNALDRLELG PIRTLMYGAI AGACTEVATY PFEVVRRQLQ
MQMGKNKLNA LAMGFNIIER GGIPALYAGL LPSLLQVLPS ASISYFVYEC MKIVLKVE
