ID   THP3_SCHPO              Reviewed;         395 AA.
AC   Q1MTP1;
DT   04-NOV-2008, integrated into UniProtKB/Swiss-Prot.
DT   30-MAY-2006, sequence version 1.
DT   25-MAY-2022, entry version 76.
DE   RecName: Full=THP3 homolog C2A9.11c;
GN   ORFNames=SPBC2A9.11c, SPBC2D10.01c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- FUNCTION: Required for transcription elongation. May also be involved
CC       in pre-mRNA splicing (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus
CC       {ECO:0000269|PubMed:16823372}.
CC   -!- SIMILARITY: Belongs to the THP3 family. {ECO:0000305}.
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DR   EMBL; CU329671; CAB39853.1; -; Genomic_DNA.
DR   RefSeq; NP_596221.1; NM_001022140.2.
DR   AlphaFoldDB; Q1MTP1; -.
DR   SMR; Q1MTP1; -.
DR   BioGRID; 276980; 25.
DR   STRING; 4896.SPBC2A9.11c.1; -.
DR   iPTMnet; Q1MTP1; -.
DR   MaxQB; Q1MTP1; -.
DR   PaxDb; Q1MTP1; -.
DR   EnsemblFungi; SPBC2A9.11c.1; SPBC2A9.11c.1:pep; SPBC2A9.11c.
DR   GeneID; 2540452; -.
DR   KEGG; spo:SPBC2A9.11c; -.
DR   PomBase; SPBC2A9.11c; -.
DR   VEuPathDB; FungiDB:SPBC2A9.11c; -.
DR   eggNOG; KOG1861; Eukaryota.
DR   HOGENOM; CLU_015513_0_0_1; -.
DR   InParanoid; Q1MTP1; -.
DR   OMA; KWATEED; -.
DR   PhylomeDB; Q1MTP1; -.
DR   PRO; PR:Q1MTP1; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0005829; C:cytosol; HDA:PomBase.
DR   GO; GO:0005634; C:nucleus; HDA:PomBase.
DR   InterPro; IPR000717; PCI_dom.
DR   InterPro; IPR045107; SAC3/GANP/THP3.
DR   InterPro; IPR005062; SAC3/GANP/THP3_conserved.
DR   PANTHER; PTHR12436; PTHR12436; 1.
DR   Pfam; PF03399; SAC3_GANP; 1.
DR   PROSITE; PS50250; PCI; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Nucleus; Reference proteome; Transcription.
FT   CHAIN           1..395
FT                   /note="THP3 homolog C2A9.11c"
FT                   /id="PRO_0000352828"
FT   DOMAIN          218..384
FT                   /note="PCI"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01185"
FT   REGION          91..127
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        93..112
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   395 AA;  46217 MW;  8F22BA9C2BAF7D8F CRC64;
     MKKEHHSPWP DSLKEFIGRC IQDAEENSQP ELEDEVKLLI SRQYEMGNIW NVDWSSMNLE
     SLRKLTNAQN TIIEDKKRKV EKPVSGNQFS LLSEEDEVDK KEKRRRRFEN GSRSQNNAKS
     EELKVNPENG AIIGRSTELE KRYLRLTSAP DPDTVRPLPV LKQTLELLKK KWKEEKNYAY
     ICDQFKSLRQ DLTVQRIQNE FSVLVYEIHA RIALEKGDVG EYNQCQTQLF HLYSFGIPGN
     TKEFLAYRIL YMLFTKNRSE MNSLLANLKE EDKTNAAVTH ALEVRSAMAT GDYYKFFHLY
     LVAPNMGGYL MDLFIERERV QAMIMMCKAY RPSLTMEFLA NTLAFEEMED CVNFFRSCNA
     VYDSKDPNRI LMKESTDRFE KCMKKHAVVD IKGQI