ID   THPA_THADA              Reviewed;          35 AA.
AC   P21381;
DT   01-MAY-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1991, sequence version 1.
DT   03-AUG-2022, entry version 59.
DE   RecName: Full=Thaumatopain;
DE            EC=3.4.22.-;
DE   Flags: Fragment;
OS   Thaumatococcus daniellii (Katemfe) (Phrynium daniellii).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Liliopsida; Zingiberales; Marantaceae;
OC   Thaumatococcus.
OX   NCBI_TaxID=4621;
RN   [1]
RP   PROTEIN SEQUENCE.
RC   TISSUE=Seed;
RX   PubMed=2001238; DOI=10.1042/bj2740231;
RA   Cusack M., Stephen A.G., Powls R., Beynon R.J.;
RT   "Purification and characterization of thaumatopain, a cysteine protease
RT   from the arils of the plant Thaumatococcus daniellii.";
RL   Biochem. J. 274:231-236(1991).
CC   -!- FUNCTION: Specificity similar to that of papain.
CC   -!- SUBUNIT: Monomer.
CC   -!- SIMILARITY: Belongs to the peptidase C1 family. {ECO:0000255|PROSITE-
CC       ProRule:PRU10088, ECO:0000255|PROSITE-ProRule:PRU10089,
CC       ECO:0000255|PROSITE-ProRule:PRU10090}.
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DR   PIR; S14329; S14329.
DR   GO; GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   InterPro; IPR038765; Papain-like_cys_pep_sf.
DR   InterPro; IPR000668; Peptidase_C1A_C.
DR   Pfam; PF00112; Peptidase_C1; 1.
DR   SUPFAM; SSF54001; SSF54001; 1.
DR   PROSITE; PS00139; THIOL_PROTEASE_CYS; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Hydrolase; Protease; Thiol protease.
FT   CHAIN           1..>35
FT                   /note="Thaumatopain"
FT                   /id="PRO_0000050570"
FT   ACT_SITE        26
FT   NON_TER         35
SQ   SEQUENCE   35 AA;  3777 MW;  C531A5C4A86D460E CRC64;
     NLPNSVDWWK KGAVAAVKNQ RXCGSCXAFS SIKTS