ID   THSB_HALSA              Reviewed;         556 AA.
AC   Q9HNI0;
DT   20-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   20-JUN-2001, sequence version 2.
DT   03-AUG-2022, entry version 112.
DE   RecName: Full=Thermosome subunit beta;
DE   AltName: Full=Chaperonin subunit beta;
DE   AltName: Full=Thermosome subunit 2;
GN   Name=thsB; Synonyms=cctB; OrderedLocusNames=VNG_2096G;
OS   Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)
OS   (Halobacterium halobium).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC   Halobacteriaceae; Halobacterium.
OX   NCBI_TaxID=64091;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700922 / JCM 11081 / NRC-1;
RX   PubMed=11016950; DOI=10.1073/pnas.190337797;
RA   Ng W.V., Kennedy S.P., Mahairas G.G., Berquist B., Pan M., Shukla H.D.,
RA   Lasky S.R., Baliga N.S., Thorsson V., Sbrogna J., Swartzell S., Weir D.,
RA   Hall J., Dahl T.A., Welti R., Goo Y.A., Leithauser B., Keller K., Cruz R.,
RA   Danson M.J., Hough D.W., Maddocks D.G., Jablonski P.E., Krebs M.P.,
RA   Angevine C.M., Dale H., Isenbarger T.A., Peck R.F., Pohlschroder M.,
RA   Spudich J.L., Jung K.-H., Alam M., Freitas T., Hou S., Daniels C.J.,
RA   Dennis P.P., Omer A.D., Ebhardt H., Lowe T.M., Liang P., Riley M., Hood L.,
RA   DasSarma S.;
RT   "Genome sequence of Halobacterium species NRC-1.";
RL   Proc. Natl. Acad. Sci. U.S.A. 97:12176-12181(2000).
CC   -!- FUNCTION: Molecular chaperone; binds unfolded polypeptides in vitro,
CC       and has a weak ATPase activity. {ECO:0000250}.
CC   -!- SUBUNIT: Forms an oligomeric complex of eight-membered rings.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TCP-1 chaperonin family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAG20240.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AE004437; AAG20240.1; ALT_INIT; Genomic_DNA.
DR   PIR; D84359; D84359.
DR   AlphaFoldDB; Q9HNI0; -.
DR   SMR; Q9HNI0; -.
DR   STRING; 64091.VNG_2096G; -.
DR   PaxDb; Q9HNI0; -.
DR   EnsemblBacteria; AAG20240; AAG20240; VNG_2096G.
DR   KEGG; hal:VNG_2096G; -.
DR   PATRIC; fig|64091.14.peg.1600; -.
DR   HOGENOM; CLU_008891_7_3_2; -.
DR   InParanoid; Q9HNI0; -.
DR   PhylomeDB; Q9HNI0; -.
DR   Proteomes; UP000000554; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   GO; GO:0051082; F:unfolded protein binding; IBA:GO_Central.
DR   GO; GO:0006457; P:protein folding; IBA:GO_Central.
DR   CDD; cd03343; cpn60; 1.
DR   Gene3D; 1.10.560.10; -; 1.
DR   Gene3D; 3.30.260.10; -; 1.
DR   Gene3D; 3.50.7.10; -; 1.
DR   InterPro; IPR017998; Chaperone_TCP-1.
DR   InterPro; IPR002194; Chaperonin_TCP-1_CS.
DR   InterPro; IPR002423; Cpn60/GroEL/TCP-1.
DR   InterPro; IPR027409; GroEL-like_apical_dom_sf.
DR   InterPro; IPR027413; GROEL-like_equatorial_sf.
DR   InterPro; IPR027410; TCP-1-like_intermed_sf.
DR   InterPro; IPR012714; Thermosome_arc.
DR   PANTHER; PTHR11353; PTHR11353; 1.
DR   Pfam; PF00118; Cpn60_TCP1; 1.
DR   PRINTS; PR00304; TCOMPLEXTCP1.
DR   SUPFAM; SSF48592; SSF48592; 1.
DR   SUPFAM; SSF52029; SSF52029; 1.
DR   SUPFAM; SSF54849; SSF54849; 1.
DR   TIGRFAMs; TIGR02339; thermosome_arch; 1.
DR   PROSITE; PS00750; TCP1_1; 1.
DR   PROSITE; PS00751; TCP1_2; 1.
DR   PROSITE; PS00995; TCP1_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Chaperone; Nucleotide-binding; Reference proteome.
FT   CHAIN           1..556
FT                   /note="Thermosome subunit beta"
FT                   /id="PRO_0000128386"
FT   REGION          530..556
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   556 AA;  58789 MW;  4FE07ADE3AEF1BE7 CRC64;
     MAQQQRMQGQ PMIIMGDDAQ RVKDRDAQEH NISAARAVAD AVRSTLGPKG MDKMLVSSMG
     DVTVTNDGVT ILQEMDIDNP TAEMIVEVAE TQEDEAGDGT TTAVAIAGEL LKNAEDLLER
     DIHPTAIIKG YNLAAEQARE EVDNVAVDVD PDDKDLIRSV AETSMTGKGA ELDKELLSSI
     IYDAVNQVAV ETNDGGIVVD AANINIETQT GHGVNESQLL RGAAISKDPV HDQMPAAVED
     ADVLLLNEAI EVEEAEADTS VNIESPDQLQ SFLDQEEKQL KEKVQQIADT GANVVFCQKG
     IDDMAQHYLA KEGILAVRRT KKSDIEFLTN VLDASVVTDL DAASEADVVA GSVTRDSDDE
     LFYVEGESEQ AHGVTLLLRG STDHVVDELE RGVSDALDVS AQTLSDGRVL PGGGATEVEV
     ASRLRDFADS VSGREQLAVE AFADSLELVP RVLAENAGLD SIDTLVDLRS AHENDDDEHI
     GLNVLSGDLE DTFEAGVVEP AHAKEQAVTS ASEAANLVLK IDDIISAGDL STDKGDDDGG
     AGGMGGGMGG GMGGMM