ID   THSB_METTH              Reviewed;         538 AA.
AC   O26885;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   03-AUG-2022, entry version 125.
DE   RecName: Full=Thermosome subunit beta;
DE   AltName: Full=Chaperonin subunit beta;
DE   AltName: Full=Thermosome subunit 2;
GN   Name=thsB; OrderedLocusNames=MTH_794;
OS   Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM
OS   10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum).
OC   Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC   Methanobacteriales; Methanobacteriaceae; Methanothermobacter.
OX   NCBI_TaxID=187420;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H;
RX   PubMed=9371463; DOI=10.1128/jb.179.22.7135-7155.1997;
RA   Smith D.R., Doucette-Stamm L.A., Deloughery C., Lee H.-M., Dubois J.,
RA   Aldredge T., Bashirzadeh R., Blakely D., Cook R., Gilbert K., Harrison D.,
RA   Hoang L., Keagle P., Lumm W., Pothier B., Qiu D., Spadafora R., Vicare R.,
RA   Wang Y., Wierzbowski J., Gibson R., Jiwani N., Caruso A., Bush D.,
RA   Safer H., Patwell D., Prabhakar S., McDougall S., Shimer G., Goyal A.,
RA   Pietrovski S., Church G.M., Daniels C.J., Mao J.-I., Rice P., Noelling J.,
RA   Reeve J.N.;
RT   "Complete genome sequence of Methanobacterium thermoautotrophicum deltaH:
RT   functional analysis and comparative genomics.";
RL   J. Bacteriol. 179:7135-7155(1997).
CC   -!- FUNCTION: Molecular chaperone; binds unfolded polypeptides in vitro,
CC       and has a weak ATPase activity. {ECO:0000250}.
CC   -!- SUBUNIT: Forms a Heterooligomeric complex of two stacked eight-membered
CC       rings. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TCP-1 chaperonin family. {ECO:0000305}.
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DR   EMBL; AE000666; AAB85294.1; -; Genomic_DNA.
DR   PIR; H69205; H69205.
DR   RefSeq; WP_010876429.1; NC_000916.1.
DR   AlphaFoldDB; O26885; -.
DR   SMR; O26885; -.
DR   STRING; 187420.MTH_794; -.
DR   EnsemblBacteria; AAB85294; AAB85294; MTH_794.
DR   GeneID; 1471202; -.
DR   KEGG; mth:MTH_794; -.
DR   PATRIC; fig|187420.15.peg.779; -.
DR   HOGENOM; CLU_008891_7_3_2; -.
DR   OMA; HPAANMI; -.
DR   Proteomes; UP000005223; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR   CDD; cd03343; cpn60; 1.
DR   Gene3D; 1.10.560.10; -; 1.
DR   Gene3D; 3.30.260.10; -; 1.
DR   Gene3D; 3.50.7.10; -; 1.
DR   InterPro; IPR017998; Chaperone_TCP-1.
DR   InterPro; IPR002194; Chaperonin_TCP-1_CS.
DR   InterPro; IPR002423; Cpn60/GroEL/TCP-1.
DR   InterPro; IPR027409; GroEL-like_apical_dom_sf.
DR   InterPro; IPR027413; GROEL-like_equatorial_sf.
DR   InterPro; IPR027410; TCP-1-like_intermed_sf.
DR   InterPro; IPR012714; Thermosome_arc.
DR   PANTHER; PTHR11353; PTHR11353; 1.
DR   Pfam; PF00118; Cpn60_TCP1; 1.
DR   PRINTS; PR00304; TCOMPLEXTCP1.
DR   SUPFAM; SSF48592; SSF48592; 1.
DR   SUPFAM; SSF52029; SSF52029; 1.
DR   SUPFAM; SSF54849; SSF54849; 1.
DR   TIGRFAMs; TIGR02339; thermosome_arch; 1.
DR   PROSITE; PS00750; TCP1_1; 1.
DR   PROSITE; PS00751; TCP1_2; 1.
DR   PROSITE; PS00995; TCP1_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Chaperone; Nucleotide-binding; Reference proteome.
FT   CHAIN           1..538
FT                   /note="Thermosome subunit beta"
FT                   /id="PRO_0000128394"
FT   REGION          518..538
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   538 AA;  57885 MW;  493CC28C552461E3 CRC64;
     MAQGQQPILV LPEGTSRYLG RDAQRMNILA GKILAETVRT TLGPKGMDKM LVDSLGDIVV
     TNDGVTILKE MDIEHPAAKM LVEVAKTQED EVGDGTTTAV IIAGELLKKA ENLLEMEIHP
     TIIAMGYRQA AEKAQEILDD IAIDASDRDT LMKVAMTAMT GKGTEKAREP LAELIVDAVK
     QVEEDGEVEK DHIKIEKKEG AAVDDSTLVQ GVIIDKERVH PGMPKKVENA KIALLNCPIE
     VKETEVDAEI RITDPSQMQA FIEQEEQMIR DMVNSIVDTG ANVLFCQKGI DDLAQHYLAK
     AGVLAVRRVK KSDMEKLSKA TGANIVTNIE DLSPEDLGEA GVVSEKKISG EEMIFVEECK
     EPKAVTILVR GSTEHVVSEV ERAIEDAIGV VAATVEDGKV VAGGGAPEIE IAKRLKDYAD
     SISGREQLAV SAFAEALEIV PKTLAENAGL DSIDVLVDLR AAHEESTYMG IDVFDGKIVD
     MKEAGVIEPH RVKKQAIQSA AEAAEMILRI DDVIAASSSG SSEEGMEEMG GMGGMPPM