ID   THSD8_HUMAN             Reviewed;         115 AA.
AC   A0A1W2PP97; A0A1W2PP18;
DT   18-JUL-2018, integrated into UniProtKB/Swiss-Prot.
DT   20-JUN-2018, sequence version 2.
DT   03-AUG-2022, entry version 23.
DE   RecName: Full=Thrombospondin type-1 domain-containing protein 8 {ECO:0000305};
DE   Flags: Precursor;
GN   Name=THSD8 {ECO:0000312|HGNC:HGNC:53785};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15057824; DOI=10.1038/nature02399;
RA   Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J., Lamerdin J.E.,
RA   Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M., Aerts A.,
RA   Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E., Caenepeel S.,
RA   Carrano A.V., Caoile C., Chan Y.M., Christensen M., Cleland C.A.,
RA   Copeland A., Dalin E., Dehal P., Denys M., Detter J.C., Escobar J.,
RA   Flowers D., Fotopulos D., Garcia C., Georgescu A.M., Glavina T., Gomez M.,
RA   Gonzales E., Groza M., Hammon N., Hawkins T., Haydu L., Ho I., Huang W.,
RA   Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Larionov V.,
RA   Leem S.-H., Lopez F., Lou Y., Lowry S., Malfatti S., Martinez D.,
RA   McCready P.M., Medina C., Morgan J., Nelson K., Nolan M., Ovcharenko I.,
RA   Pitluck S., Pollard M., Popkie A.P., Predki P., Quan G., Ramirez L.,
RA   Rash S., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A.,
RA   She X., Smith D., Slezak T., Solovyev V., Thayer N., Tice H., Tsai M.,
RA   Ustaszewska A., Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J.,
RA   Dubchak I., Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA   Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA   Rubin E.M., Lucas S.M.;
RT   "The DNA sequence and biology of human chromosome 19.";
RL   Nature 428:529-535(2004).
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DR   EMBL; AC018761; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC020934; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; A0A1W2PP97; -.
DR   BioMuta; ENSG00000284491; -.
DR   Ensembl; ENST00000639767.2; ENSP00000491410.2; ENSG00000284491.3.
DR   Ensembl; ENST00000639810.3; ENSP00000491231.1; ENSG00000284491.3.
DR   MANE-Select; ENST00000639810.3; ENSP00000491231.1; NM_001386800.1; NP_001373729.1.
DR   GeneCards; THSD8; -.
DR   HGNC; HGNC:53785; THSD8.
DR   HPA; ENSG00000284491; Tissue enhanced (testis).
DR   neXtProt; NX_A0A1W2PP97; -.
DR   VEuPathDB; HostDB:ENSG00000284491; -.
DR   GeneTree; ENSGT00870000137755; -.
DR   OMA; MDPENLI; -.
DR   Pharos; A0A1W2PP97; Tdark.
DR   PRO; PR:A0A1W2PP97; -.
DR   Proteomes; UP000005640; Chromosome 19.
DR   Bgee; ENSG00000284491; Expressed in left testis and 88 other tissues.
DR   InterPro; IPR000884; TSP1_rpt.
DR   InterPro; IPR036383; TSP1_rpt_sf.
DR   SUPFAM; SSF82895; SSF82895; 1.
DR   PROSITE; PS50092; TSP1; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Signal.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000255"
FT   CHAIN           22..115
FT                   /note="Thrombospondin type-1 domain-containing protein 8"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000444945"
FT   DOMAIN          53..104
FT                   /note="TSP type-1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00210"
SQ   SEQUENCE   115 AA;  13152 MW;  5BE52FCDC5935CCD CRC64;
     MARTPGALLL APLLLLQLAT PALVYQDYQY LGQQGEGDSW EQLRLQHLKE VEDSILGPWG
     KWRCLCDLGK QERSREVVGT APGPVFMDPE KLIQLRPCRQ RDCPSCKPFD CDWRL