ID   THS_METJA               Reviewed;         542 AA.
AC   Q58405;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 113.
DE   RecName: Full=Thermosome subunit;
DE   AltName: Full=Chaperonin subunit;
GN   Name=ths; OrderedLocusNames=MJ0999;
OS   Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM
OS   10045 / NBRC 100440) (Methanococcus jannaschii).
OC   Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC   Methanocaldococcaceae; Methanocaldococcus.
OX   NCBI_TaxID=243232;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX   PubMed=8688087; DOI=10.1126/science.273.5278.1058;
RA   Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G.,
RA   Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R.,
RA   Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R.,
RA   Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., Scott J.L.,
RA   Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R.,
RA   Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D.,
RA   Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P.,
RA   Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
RT   "Complete genome sequence of the methanogenic archaeon, Methanococcus
RT   jannaschii.";
RL   Science 273:1058-1073(1996).
CC   -!- FUNCTION: Molecular chaperone; binds unfolded polypeptides in vitro,
CC       and has a weak ATPase activity. {ECO:0000250}.
CC   -!- SUBUNIT: Forms an oligomeric complex of eight-membered rings.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TCP-1 chaperonin family. {ECO:0000305}.
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DR   EMBL; L77117; AAB99002.1; -; Genomic_DNA.
DR   PIR; F64424; F64424.
DR   RefSeq; WP_010870512.1; NC_000909.1.
DR   AlphaFoldDB; Q58405; -.
DR   SMR; Q58405; -.
DR   STRING; 243232.MJ_0999; -.
DR   EnsemblBacteria; AAB99002; AAB99002; MJ_0999.
DR   GeneID; 1451896; -.
DR   KEGG; mja:MJ_0999; -.
DR   eggNOG; arCOG01257; Archaea.
DR   HOGENOM; CLU_008891_7_3_2; -.
DR   InParanoid; Q58405; -.
DR   OMA; HPAANMI; -.
DR   OrthoDB; 11742at2157; -.
DR   PhylomeDB; Q58405; -.
DR   Proteomes; UP000000805; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   GO; GO:0051082; F:unfolded protein binding; IBA:GO_Central.
DR   GO; GO:0006457; P:protein folding; IBA:GO_Central.
DR   CDD; cd03343; cpn60; 1.
DR   Gene3D; 1.10.560.10; -; 1.
DR   Gene3D; 3.30.260.10; -; 1.
DR   Gene3D; 3.50.7.10; -; 1.
DR   InterPro; IPR017998; Chaperone_TCP-1.
DR   InterPro; IPR002194; Chaperonin_TCP-1_CS.
DR   InterPro; IPR002423; Cpn60/GroEL/TCP-1.
DR   InterPro; IPR027409; GroEL-like_apical_dom_sf.
DR   InterPro; IPR027413; GROEL-like_equatorial_sf.
DR   InterPro; IPR027410; TCP-1-like_intermed_sf.
DR   InterPro; IPR012714; Thermosome_arc.
DR   PANTHER; PTHR11353; PTHR11353; 1.
DR   Pfam; PF00118; Cpn60_TCP1; 1.
DR   PRINTS; PR00304; TCOMPLEXTCP1.
DR   SUPFAM; SSF48592; SSF48592; 1.
DR   SUPFAM; SSF52029; SSF52029; 1.
DR   SUPFAM; SSF54849; SSF54849; 1.
DR   TIGRFAMs; TIGR02339; thermosome_arch; 1.
DR   PROSITE; PS00750; TCP1_1; 1.
DR   PROSITE; PS00751; TCP1_2; 1.
DR   PROSITE; PS00995; TCP1_3; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Chaperone; Nucleotide-binding; Reference proteome.
FT   CHAIN           1..542
FT                   /note="Thermosome subunit"
FT                   /id="PRO_0000128390"
SQ   SEQUENCE   542 AA;  58772 MW;  D505F08531D4668D CRC64;
     MAMAGAPIVV LPQNVKRYVG RDAQRMNILA GRIIAETVRT TLGPKGMDKM LVDELGDIVV
     TNDGVTILKE MSVEHPAAKM LIEVAKTQEK EVGDGTTTAV VIAGELLRKA EELLDQNIHP
     SVIINGYEMA RNKAVEELKS IAKEVKPEDT EMLKKIAMTS ITGKGAEKAR EQLAEIVVEA
     VRAVVDEETG KVDKDLIKVE KKEGAPIEET KLIRGVVIDK ERVNPQMPKK VENAKIALLN
     CPIEVKETET DAEIRITDPA KLMEFIEQEE KMIKDMVEKI AATGANVVFC QKGIDDLAQH
     YLAKKGILAV RRVKKSDMEK LAKATGARIV TKIDDLTPED LGEAGLVEER KVAGDAMIFV
     EQCKHPKAVT ILARGSTEHV VEEVARAIDD AIGVVKCALE EGKIVAGGGA TEIELAKRLR
     KFAESVAGRE QLAVKAFADA LEVIPRTLAE NSGLDPIDML VKLRAAHEKE GGEVYGLDVF
     EGEVVDMLEK GVVEPLKVKT QAIDSATEAS VMLLRIDDVI AAEKVKGDEK GGEGGDMGGD
     EF