THYN1_DANRE
ID THYN1_DANRE Reviewed; 231 AA.
AC Q6PFL8;
DT 28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 84.
DE RecName: Full=Thymocyte nuclear protein 1;
GN Name=thyn1; ORFNames=zgc:66269;
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=SJD;
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (SEP-2003) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting
CC that it acts as a specific reader of 5hmC. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- PTM: Phosphorylated. {ECO:0000250}.
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DR EMBL; BC057500; AAH57500.1; -; mRNA.
DR AlphaFoldDB; Q6PFL8; -.
DR SMR; Q6PFL8; -.
DR STRING; 7955.ENSDARP00000062575; -.
DR PaxDb; Q6PFL8; -.
DR PRIDE; Q6PFL8; -.
DR ZFIN; ZDB-GENE-040426-1585; thyn1.
DR eggNOG; KOG3383; Eukaryota.
DR InParanoid; Q6PFL8; -.
DR PhylomeDB; Q6PFL8; -.
DR PRO; PR:Q6PFL8; -.
DR Proteomes; UP000000437; Genome assembly.
DR Proteomes; UP000814640; Unplaced.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR InterPro; IPR002740; EVE_domain.
DR InterPro; IPR015947; PUA-like_sf.
DR Pfam; PF01878; EVE; 1.
DR SUPFAM; SSF88697; SSF88697; 1.
PE 2: Evidence at transcript level;
KW Nucleus; Phosphoprotein; Reference proteome.
FT CHAIN 1..231
FT /note="Thymocyte nuclear protein 1"
FT /id="PRO_0000262568"
FT REGION 1..54
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 4..11
FT /note="Nuclear localization signal"
FT /evidence="ECO:0000250"
FT COMPBIAS 10..54
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 231 AA; 26513 MW; B6A42024E0B6E9CB CRC64;
MPPRKTRSSA KSNKHSDADA HLNEGSDDVA QRKTGKRKRS AAVKGDVENK NDDDACKPSY
SRWLMKSEPE SRIENGVDVK FGIEDLKALP NQTGCWDGVR NYQARNFMRE MKVGQQAFFY
HSNCKEPGIA GLMKIVKEAY VDHTQFDKKD VHYDPSSKAD NPKWHMVDVQ FERMVKRFIP
LAELKKYHLE HRVKGGPLKD MALFTRARLS VQPLTAEEFE FVLSLENEDP I