ID   THYN1_RAT               Reviewed;         226 AA.
AC   Q6P3E0;
DT   28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 90.
DE   RecName: Full=Thymocyte nuclear protein 1;
GN   Name=Thyn1;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Pituitary;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- FUNCTION: Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting
CC       that it acts as a specific reader of 5hmC. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- PTM: Phosphorylated. {ECO:0000250}.
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DR   EMBL; BC064031; AAH64031.1; -; mRNA.
DR   RefSeq; NP_001007662.1; NM_001007661.2.
DR   AlphaFoldDB; Q6P3E0; -.
DR   SMR; Q6P3E0; -.
DR   STRING; 10116.ENSRNOP00000067377; -.
DR   PhosphoSitePlus; Q6P3E0; -.
DR   PaxDb; Q6P3E0; -.
DR   GeneID; 300470; -.
DR   KEGG; rno:300470; -.
DR   CTD; 29087; -.
DR   RGD; 1359525; Thyn1.
DR   VEuPathDB; HostDB:ENSRNOG00000047053; -.
DR   eggNOG; KOG3383; Eukaryota.
DR   HOGENOM; CLU_041799_2_0_1; -.
DR   InParanoid; Q6P3E0; -.
DR   OMA; DVQFIRM; -.
DR   OrthoDB; 1522853at2759; -.
DR   PhylomeDB; Q6P3E0; -.
DR   PRO; PR:Q6P3E0; -.
DR   Proteomes; UP000002494; Chromosome 8.
DR   Bgee; ENSRNOG00000047053; Expressed in ovary and 19 other tissues.
DR   Genevisible; Q6P3E0; RN.
DR   GO; GO:0005634; C:nucleus; ISO:RGD.
DR   InterPro; IPR002740; EVE_domain.
DR   InterPro; IPR015947; PUA-like_sf.
DR   Pfam; PF01878; EVE; 1.
DR   SUPFAM; SSF88697; SSF88697; 1.
PE   2: Evidence at transcript level;
KW   Nucleus; Phosphoprotein; Reference proteome.
FT   CHAIN           1..226
FT                   /note="Thymocyte nuclear protein 1"
FT                   /id="PRO_0000262566"
FT   REGION          1..38
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOTIF           5..10
FT                   /note="Nuclear localization signal"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   226 AA;  26123 MW;  F868225C85A49EEE CRC64;
     MPRPRKRQAG AAGPDKKQLS GKRTKTENSE SASVKLENSS LEKTTTFKTC GKNLSNYWLM
     KSEPESRLEK GIDMKFSIED LQAQPKQTTC WDGVRNYQAW NFLRAMKLED EAFFYHSNCK
     QPGIVGLMKI VKEAYPDHTQ FEKNDPHYDP SSKEDNPKWS MVDVQFVRMM KRFISLDELK
     TYHQAHKATG GPLKSMTLFT RQRLSVQPLT QEEFDFILSL EEAEPS