BRXL1_ARATH
ID BRXL1_ARATH Reviewed; 331 AA.
AC O82281; Q8LAY6;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2002, sequence version 2.
DT 25-MAY-2022, entry version 96.
DE RecName: Full=Protein Brevis radix-like 1;
DE Short=AtBRXL1;
GN Name=BRXL1; OrderedLocusNames=At2g35600; ORFNames=T32F12.2;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP IDENTIFICATION.
RX PubMed=15031265; DOI=10.1101/gad.1187704;
RA Mouchel C.F., Briggs G.C., Hardtke C.S.;
RT "Natural genetic variation in Arabidopsis identifies BREVIS RADIX, a novel
RT regulator of cell proliferation and elongation in the root.";
RL Genes Dev. 18:700-714(2004).
RN [5]
RP GENE FAMILY, FUNCTION, DISRUPTION PHENOTYPE, AND TISSUE SPECIFICITY.
RX PubMed=16514016; DOI=10.1104/pp.105.075382;
RA Briggs G.C., Mouchel C.F., Hardtke C.S.;
RT "Characterization of the plant-specific BREVIS RADIX gene family reveals
RT limited genetic redundancy despite high sequence conservation.";
RL Plant Physiol. 140:1306-1316(2006).
CC -!- FUNCTION: May act as a regulator of cell proliferation and elongation
CC in the root. {ECO:0000269|PubMed:16514016}.
CC -!- SUBUNIT: Heterodimer with BRXL1.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC -!- TISSUE SPECIFICITY: Expressed in roots. {ECO:0000269|PubMed:16514016}.
CC -!- DISRUPTION PHENOTYPE: No visible phenotype.
CC {ECO:0000269|PubMed:16514016}.
CC -!- MISCELLANEOUS: Overexpression of BRXL1 can rescue the short root
CC phenotype. However, it does not act redundantly with BRX in vivo,
CC presumably due to a much lower level of expression.
CC -!- SIMILARITY: Belongs to the BRX family. {ECO:0000305}.
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DR EMBL; AC005314; AAC36161.2; -; Genomic_DNA.
DR EMBL; AC006068; AAM15118.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC09126.1; -; Genomic_DNA.
DR EMBL; CP002685; ANM61846.1; -; Genomic_DNA.
DR EMBL; CP002685; ANM61847.1; -; Genomic_DNA.
DR EMBL; AY087525; AAM65067.1; -; mRNA.
DR PIR; F84770; F84770.
DR RefSeq; NP_001324041.1; NM_001336562.1.
DR RefSeq; NP_001324042.1; NM_001336563.1.
DR RefSeq; NP_565809.1; NM_129113.5.
DR AlphaFoldDB; O82281; -.
DR SMR; O82281; -.
DR STRING; 3702.AT2G35600.1; -.
DR PaxDb; O82281; -.
DR PRIDE; O82281; -.
DR ProteomicsDB; 240480; -.
DR EnsemblPlants; AT2G35600.1; AT2G35600.1; AT2G35600.
DR EnsemblPlants; AT2G35600.2; AT2G35600.2; AT2G35600.
DR EnsemblPlants; AT2G35600.3; AT2G35600.3; AT2G35600.
DR GeneID; 818126; -.
DR Gramene; AT2G35600.1; AT2G35600.1; AT2G35600.
DR Gramene; AT2G35600.2; AT2G35600.2; AT2G35600.
DR Gramene; AT2G35600.3; AT2G35600.3; AT2G35600.
DR KEGG; ath:AT2G35600; -.
DR Araport; AT2G35600; -.
DR TAIR; locus:2058694; AT2G35600.
DR eggNOG; ENOG502QU4N; Eukaryota.
DR HOGENOM; CLU_033380_0_1_1; -.
DR InParanoid; O82281; -.
DR OMA; NCTKMAD; -.
DR OrthoDB; 773657at2759; -.
DR PhylomeDB; O82281; -.
DR PRO; PR:O82281; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; O82281; baseline and differential.
DR Genevisible; O82281; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR InterPro; IPR013591; Brevis_radix_dom.
DR InterPro; IPR044532; BRX-like.
DR InterPro; IPR027988; BRX_N.
DR PANTHER; PTHR46058; PTHR46058; 1.
DR Pfam; PF08381; BRX; 2.
DR Pfam; PF13713; BRX_N; 1.
DR PROSITE; PS51514; BRX; 2.
PE 2: Evidence at transcript level;
KW Nucleus; Reference proteome; Repeat.
FT CHAIN 1..331
FT /note="Protein Brevis radix-like 1"
FT /id="PRO_0000373822"
FT DOMAIN 137..192
FT /note="BRX 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00847"
FT DOMAIN 276..331
FT /note="BRX 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00847"
FT REGION 1..111
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 201..246
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 258..279
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 27..71
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 81..111
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 212..232
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 260..274
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 238
FT /note="P -> S (in Ref. 3; AAM65067)"
FT /evidence="ECO:0000305"
FT CONFLICT 320
FT /note="E -> D (in Ref. 3; AAM65067)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 331 AA; 38005 MW; 733E036413F98125 CRC64;
MFTCINCTKM ADRGEEDEED EARGSTTPNT KEAVKSLTTQ IKDMASKFSG SHKQSKPTPG
SSSSNLRKFP DFDTASESVP YPYPGGSTSS TPAWDLPRSS YHQSGRPDSR FTSMYGGERE
SISAQSCDVV LEDDEPKEWM AQVEPGVHIT FVSLPSGGND LKRIRFSREV FDKWQAQRWW
GENYDRIVEL YNVQRFNRQA LQTPGRSEDQ SQRDSTYTRI DSARESRDWT QRDNNFRPPG
GSVPHHFYGP PMDAARITTS SRDEPPSMSN ASEMQGEWVE EDEPGVYITI RQLPDGTREL
RRVRFSRERF GEVHAKTWWE QNRDRIQTQY L
