ID   TI16A_XENLA             Reviewed;         125 AA.
AC   Q6NTU3;
DT   06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 75.
DE   RecName: Full=Mitochondrial import inner membrane translocase subunit tim16-A;
DE   AltName: Full=Presequence translocated-associated motor subunit pam16-A;
GN   Name=pam16-a; Synonyms=tim16-a, timm16-a;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (APR-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Regulates ATP-dependent protein translocation into the
CC       mitochondrial matrix. {ECO:0000250}.
CC   -!- SUBUNIT: Probable component of the PAM complex at least composed of 1
CC       mitochondrial HSP70 protein, 1 GRPE, 1 TIMM44, 1 TIMM16/PAM16 and 1
CC       TIMM14. Associates with the TIM23 complex. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC       Peripheral membrane protein {ECO:0000250}; Matrix side {ECO:0000250}.
CC   -!- DOMAIN: The J-like region, although related to the J domain does not
CC       have co-chaperone activity. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TIM16/PAM16 family. {ECO:0000305}.
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DR   EMBL; BC068861; AAH68861.1; -; mRNA.
DR   RefSeq; NP_001084733.1; NM_001091264.1.
DR   AlphaFoldDB; Q6NTU3; -.
DR   SMR; Q6NTU3; -.
DR   DNASU; 414698; -.
DR   GeneID; 414698; -.
DR   KEGG; xla:414698; -.
DR   CTD; 414698; -.
DR   Xenbase; XB-GENE-6252269; pam16.L.
DR   OMA; RMFKIND; -.
DR   OrthoDB; 1640138at2759; -.
DR   Proteomes; UP000186698; Chromosome 9_10L.
DR   Bgee; 414698; Expressed in muscle tissue and 19 other tissues.
DR   GO; GO:0005744; C:TIM23 mitochondrial import inner membrane translocase complex; IEA:InterPro.
DR   GO; GO:0030150; P:protein import into mitochondrial matrix; IEA:InterPro.
DR   Gene3D; 1.10.287.110; -; 1.
DR   InterPro; IPR036869; J_dom_sf.
DR   InterPro; IPR005341; Tim16.
DR   PANTHER; PTHR12388; PTHR12388; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Mitochondrion; Mitochondrion inner membrane; Protein transport;
KW   Reference proteome; Translocation; Transport.
FT   CHAIN           1..125
FT                   /note="Mitochondrial import inner membrane translocase
FT                   subunit tim16-A"
FT                   /id="PRO_0000214082"
FT   REGION          58..110
FT                   /note="J-like"
SQ   SEQUENCE   125 AA;  13843 MW;  B3899C18407CBA9B CRC64;
     MAKYLAQIVV MGMQVVGRAF TRALRQEFAA SKVAAEARGR AGTESAAVSS LSGISLQEAQ
     QILNVSKLTP EEIQKNYEHL FKVNDKGLGG SFYLQSKVVR AKERLDQEME IQSKTHKPKE
     ETTQT