ID   BRXL4_ARATH             Reviewed;         384 AA.
AC   Q8GZ92;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=Protein Brevis radix-like 4;
DE            Short=AtBRXL4;
GN   Name=BRXL4; OrderedLocusNames=At5g20540; ORFNames=F7C8.130;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130714; DOI=10.1038/35048507;
RA   Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA   Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA   Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA   Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA   Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA   O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA   Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA   Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA   Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA   Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA   Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA   Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D.,
RA   Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA   Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA   Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA   Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A.,
RA   McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U.,
RA   Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W.,
RA   Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M.,
RA   Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S.,
RA   Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G.,
RA   Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W.,
RA   Bevan M., Fransz P.F.;
RT   "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL   Nature 408:823-826(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11910074; DOI=10.1126/science.1071006;
RA   Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA   Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA   Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA   Shinagawa A., Shinozaki K.;
RT   "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL   Science 296:141-145(2002).
RN   [4]
RP   IDENTIFICATION.
RX   PubMed=15031265; DOI=10.1101/gad.1187704;
RA   Mouchel C.F., Briggs G.C., Hardtke C.S.;
RT   "Natural genetic variation in Arabidopsis identifies BREVIS RADIX, a novel
RT   regulator of cell proliferation and elongation in the root.";
RL   Genes Dev. 18:700-714(2004).
RN   [5]
RP   GENE FAMILY, AND TISSUE SPECIFICITY.
RX   PubMed=16514016; DOI=10.1104/pp.105.075382;
RA   Briggs G.C., Mouchel C.F., Hardtke C.S.;
RT   "Characterization of the plant-specific BREVIS RADIX gene family reveals
RT   limited genetic redundancy despite high sequence conservation.";
RL   Plant Physiol. 140:1306-1316(2006).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- TISSUE SPECIFICITY: Expressed in roots. {ECO:0000269|PubMed:16514016}.
CC   -!- SIMILARITY: Belongs to the BRX family. {ECO:0000305}.
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DR   EMBL; AF296833; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CP002688; AED92856.1; -; Genomic_DNA.
DR   EMBL; AK117133; BAC41811.1; -; mRNA.
DR   RefSeq; NP_197554.2; NM_122061.4.
DR   AlphaFoldDB; Q8GZ92; -.
DR   SMR; Q8GZ92; -.
DR   STRING; 3702.AT5G20540.1; -.
DR   iPTMnet; Q8GZ92; -.
DR   PaxDb; Q8GZ92; -.
DR   PRIDE; Q8GZ92; -.
DR   ProteomicsDB; 240509; -.
DR   EnsemblPlants; AT5G20540.1; AT5G20540.1; AT5G20540.
DR   GeneID; 832176; -.
DR   Gramene; AT5G20540.1; AT5G20540.1; AT5G20540.
DR   KEGG; ath:AT5G20540; -.
DR   Araport; AT5G20540; -.
DR   TAIR; locus:2149897; AT5G20540.
DR   eggNOG; ENOG502QQJI; Eukaryota.
DR   HOGENOM; CLU_033380_0_1_1; -.
DR   InParanoid; Q8GZ92; -.
DR   OMA; EREPKEW; -.
DR   OrthoDB; 995616at2759; -.
DR   PhylomeDB; Q8GZ92; -.
DR   PRO; PR:Q8GZ92; -.
DR   Proteomes; UP000006548; Chromosome 5.
DR   ExpressionAtlas; Q8GZ92; baseline and differential.
DR   Genevisible; Q8GZ92; AT.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   InterPro; IPR013591; Brevis_radix_dom.
DR   InterPro; IPR044532; BRX-like.
DR   InterPro; IPR027988; BRX_N.
DR   PANTHER; PTHR46058; PTHR46058; 1.
DR   Pfam; PF08381; BRX; 2.
DR   Pfam; PF13713; BRX_N; 1.
DR   PROSITE; PS51514; BRX; 2.
PE   2: Evidence at transcript level;
KW   Nucleus; Reference proteome; Repeat.
FT   CHAIN           1..384
FT                   /note="Protein Brevis radix-like 4"
FT                   /id="PRO_0000373825"
FT   DOMAIN          150..205
FT                   /note="BRX 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00847"
FT   DOMAIN          329..384
FT                   /note="BRX 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00847"
FT   REGION          1..35
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          50..78
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          214..270
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          304..325
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        52..76
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   384 AA;  42883 MW;  2C6C38B71B592BCF CRC64;
     MLTCIARSKR AGDESSGQPD DPDSKNAKSL TSQLKDMALK ASGAYRHCTP CTAAQGQGQG
     QGPIKNNPSS SSVKSDFESD QRFKMLYGRS NSSITATAAV AATQQQQPRV WGKEMEARLK
     GISSGEATPK SASGRNRVDP IVFVEEKEPK EWVAQVEPGV LITFVSLPGG GNDLKRIRFS
     RDMFNKLQAQ RWWADNYDKV MELYNVQKLS RQAFPLPTPP RSEDENAKVE YHPEDTPATP
     PLNKERLPRT IHRPPGLAAY SSSDSLDHNS MQSQQFYDSG LLNSTPKVSS ISVAKTETSS
     IDASIRSSSS RDADRSEEMS VSNASDVDNE WVEQDEPGVY ITIKVLPGGK RELRRVRFSR
     ERFGEMHARL WWEENRARIH EQYL