TI202_ARATH
ID TI202_ARATH Reviewed; 208 AA.
AC O82251; Q94A61;
DT 19-OCT-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1998, sequence version 1.
DT 03-AUG-2022, entry version 97.
DE RecName: Full=Protein TIC 20-II, chloroplastic;
DE AltName: Full=Translocon at the inner envelope membrane of chloroplasts 20-II;
DE Short=AtTIC20-II;
DE Flags: Precursor;
GN Name=TIC20-II; OrderedLocusNames=At2g47840; ORFNames=F17A22.23;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP SUBCELLULAR LOCATION, TISSUE SPECIFICITY, DEVELOPMENTAL STAGE, AND
RP DISRUPTION PHENOTYPE.
RX PubMed=21395885; DOI=10.1111/j.1365-313x.2011.04551.x;
RA Kasmati A.R., Toepel M., Patel R., Murtaza G., Jarvis P.;
RT "Molecular and genetic analyses of Tic20 homologues in Arabidopsis thaliana
RT chloroplasts.";
RL Plant J. 66:877-889(2011).
RN [5]
RP REVIEW.
RX PubMed=20100520; DOI=10.1016/j.bbamcr.2010.01.015;
RA Kovacs-Bogdan E., Soll J., Bolter B.;
RT "Protein import into chloroplasts: the Tic complex and its regulation.";
RL Biochim. Biophys. Acta 1803:740-747(2010).
CC -!- FUNCTION: May be involved in protein precursor import into
CC chloroplasts. Not redundant with TIC20-I, TIC20-IV or TIC20-V.
CC -!- SUBUNIT: Part of the Tic complex. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast inner membrane
CC {ECO:0000269|PubMed:21395885}; Multi-pass membrane protein
CC {ECO:0000269|PubMed:21395885}.
CC -!- TISSUE SPECIFICITY: Expressed in leaves, siliques and roots.
CC {ECO:0000269|PubMed:21395885}.
CC -!- DEVELOPMENTAL STAGE: Expressed throughout development.
CC {ECO:0000269|PubMed:21395885}.
CC -!- DISRUPTION PHENOTYPE: No visible phenotype.
CC {ECO:0000269|PubMed:21395885}.
CC -!- SIMILARITY: Belongs to the Tic20 family. {ECO:0000305}.
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DR EMBL; AC005309; AAC63638.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC10895.1; -; Genomic_DNA.
DR EMBL; AY050346; AAK91363.1; -; mRNA.
DR EMBL; AY094045; AAM16201.1; -; mRNA.
DR PIR; B84920; B84920.
DR RefSeq; NP_566112.1; NM_130351.3.
DR AlphaFoldDB; O82251; -.
DR BioGRID; 4731; 2.
DR IntAct; O82251; 2.
DR STRING; 3702.AT2G47840.1; -.
DR PaxDb; O82251; -.
DR PRIDE; O82251; -.
DR ProteomicsDB; 246486; -.
DR EnsemblPlants; AT2G47840.1; AT2G47840.1; AT2G47840.
DR GeneID; 819396; -.
DR Gramene; AT2G47840.1; AT2G47840.1; AT2G47840.
DR KEGG; ath:AT2G47840; -.
DR Araport; AT2G47840; -.
DR TAIR; locus:2043353; AT2G47840.
DR eggNOG; ENOG502QUSD; Eukaryota.
DR HOGENOM; CLU_094758_0_0_1; -.
DR InParanoid; O82251; -.
DR OMA; IFACLPY; -.
DR OrthoDB; 1441544at2759; -.
DR PhylomeDB; O82251; -.
DR PRO; PR:O82251; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; O82251; baseline and differential.
DR Genevisible; O82251; AT.
DR GO; GO:0009507; C:chloroplast; HDA:TAIR.
DR GO; GO:0009941; C:chloroplast envelope; HDA:TAIR.
DR GO; GO:0009706; C:chloroplast inner membrane; IDA:TAIR.
DR GO; GO:0005829; C:cytosol; HDA:TAIR.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0009536; C:plastid; HDA:TAIR.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR InterPro; IPR005691; Tic20.
DR PANTHER; PTHR33510; PTHR33510; 1.
DR Pfam; PF16166; TIC20; 1.
PE 2: Evidence at transcript level;
KW Chloroplast; Membrane; Plastid; Plastid inner membrane; Protein transport;
KW Reference proteome; Transit peptide; Transmembrane; Transmembrane helix;
KW Transport.
FT TRANSIT 1..49
FT /note="Chloroplast"
FT /evidence="ECO:0000255"
FT CHAIN 50..208
FT /note="Protein TIC 20-II, chloroplastic"
FT /id="PRO_0000413664"
FT TRANSMEM 61..83
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 101..121
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 134..154
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 172..192
FT /note="Helical"
FT /evidence="ECO:0000255"
FT CONFLICT 36
FT /note="I -> T (in Ref. 3; AAK91363/AAM16201)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 208 AA; 22912 MW; 0A6543B6FCACBEF4 CRC64;
MASLCLSLHQ TLTNPLSAPR CRPLSLSFPG SSTFSIRPSS RRATALTTRA SYTPTPATER
VISIASYALP FFNSLQYGRF LFAQYPRLGL LFEPIFPILN LYRSVPYASF VAFFGLYLGV
VRNTSFSRYV RFNAMQAVTL DVLLAVPVLL TRILDPGQGG GFGMKAMMWG HTGVFVFSFM
CFVYGVVSSL LGKTPYIPFV ADAAGRQL
