ID   TI214_ADICA             Reviewed;        1691 AA.
AC   Q85FG7;
DT   05-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 2.
DT   25-MAY-2022, entry version 53.
DE   RecName: Full=Protein TIC 214 {ECO:0000250|UniProtKB:P56785};
DE   AltName: Full=Translocon at the inner envelope membrane of chloroplasts 214 {ECO:0000250|UniProtKB:P56785};
DE            Short=AtTIC214 {ECO:0000250|UniProtKB:P56785};
GN   Name=TIC214 {ECO:0000250|UniProtKB:P56785}; Synonyms=ycf1;
OS   Adiantum capillus-veneris (Maidenhair fern).
OG   Plastid; Chloroplast.
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Polypodiopsida; Polypodiidae; Polypodiales; Pteridineae; Pteridaceae;
OC   Vittarioideae; Adiantum.
OX   NCBI_TaxID=13818;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12755170; DOI=10.1093/dnares/10.2.59;
RA   Wolf P.G., Rowe C.A., Sinclair R.B., Hasebe M.;
RT   "Complete nucleotide sequence of the chloroplast genome from a
RT   leptosporangiate fern, Adiantum capillus-veneris L.";
RL   DNA Res. 10:59-65(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND RNA EDITING.
RC   TISSUE=Frond;
RX   PubMed=15363849; DOI=10.1016/j.gene.2004.06.018;
RA   Wolf P.G., Rowe C.A., Hasebe M.;
RT   "High levels of RNA editing in a vascular plant chloroplast genome:
RT   analysis of transcripts from the fern Adiantum capillus-veneris.";
RL   Gene 339:89-97(2004).
CC   -!- FUNCTION: Involved in protein precursor import into chloroplasts. May
CC       be part of an intermediate translocation complex acting as a protein-
CC       conducting channel at the inner envelope.
CC       {ECO:0000250|UniProtKB:P56785}.
CC   -!- SUBUNIT: Part of the Tic complex. {ECO:0000250|UniProtKB:P56785}.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast inner membrane
CC       {ECO:0000250|UniProtKB:P56785}; Multi-pass membrane protein
CC       {ECO:0000255}.
CC   -!- RNA EDITING: Modified_positions=1 {ECO:0000269|PubMed:15363849};
CC       Note=The initiator methionine is created by RNA editing.;
CC   -!- SIMILARITY: Belongs to the TIC214 family. {ECO:0000305}.
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DR   EMBL; AY178864; AAP29449.2; -; Genomic_DNA.
DR   RefSeq; NP_848118.2; NC_004766.1.
DR   AlphaFoldDB; Q85FG7; -.
DR   PRIDE; Q85FG7; -.
DR   GeneID; 807449; -.
DR   GO; GO:0009706; C:chloroplast inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR008896; TIC214.
DR   PANTHER; PTHR33163; PTHR33163; 3.
DR   Pfam; PF05758; Ycf1; 3.
PE   2: Evidence at transcript level;
KW   Chloroplast; Membrane; Plastid; Plastid inner membrane; Protein transport;
KW   RNA editing; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..1691
FT                   /note="Protein TIC 214"
FT                   /id="PRO_0000217296"
FT   TRANSMEM        19..39
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        60..80
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        84..104
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        123..143
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        158..178
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        200..220
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          819..839
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        819..837
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1691 AA;  198957 MW;  0E80EE681C8A000E CRC64;
     MNTKILLSLP WPKLMDPYML LGFYYGLLTT LPVGPSQILC VRSFLLGGNL SGLISISGSV
     LAQLITASSI YCSPIYLLLL RPHLLTIVAI PYTLLFCLVI KDFPNYQILR PVTSLRDSRV
     ARLFLISFFF QILNPIMLPN SVLTRLIYLY FFRYSTNTVF MVSTFMGWLT GQAAFNFFSR
     LLLSRVKGDS PILYLVAKRF IYATFSIVSI SYAVAYLGRA PVSFWTKKFM NESHDREMNL
     WEIAEYSDLL WWFFKPWPTS FFDPSRANRS NRFVKNRRFH MNNTFYKGRT STYFFEKCLT
     DGKERLSFLA LPSLSIFGKE MYQSMAKSRR SFGIRLSYQN WVSKKLAKTK FFEKELTDQI
     KLLDTGSSFS KTMSRKTRLM GGKRRRIPRT YDPFVNNFRI RIPVSQTFLL EDDLGLSLWE
     WDKLATERKN RKAKKTVRIN AIKDKIFTKD RRWKHGYGNP LPWEPLPSRS KRMFYFIFEN
     RALYDYDLQN ILKKIKSSPT LDVTWKEIMD LDYEDHILFL TYLEVGCCHR FGWISPLKAF
     LRKSSKSLSN VERRIRRLNK IGNLSMDLAR YTILYFENNF DIPGGDGDFR YRKLRNVGIT
     FAKGKPRSER LMKRYAKVSD FRRKFLKGSM RSRRRKTLLW KALQEKIRSS FFLRSAERTI
     LFQSLIERLT TSSREEKFSE LEKDTDYEFQ KQLLDISLSA KRSLIGESKL TRSAIAARSD
     IGPIHNGRGY MLVFQSRFRK FIKLPVLIVL KNIGRILLRQ NSEWNKDWTG WKKEIHINCT
     FDGEDFSQDE LPPRWLREGI QIKIVYPFQL KPWHTDGNEK QHTLQRKHKE IGSKSRELKS
     KRKLKQKKHK FTYLTVLGYQ TDIPFGTIQK KTSFWKPVRR KLIRICKRSL PRQIKQAYQF
     IHSRFEKVSK LNSTPSKKLN LISNLRQGGK LLSDYSLDEK SWMKTSSTNY VNEKTKPNCN
     VISNSERFIA IGGEMSPANV TRKQLVTRDQ VEREFLMSIV AVDSKNLLDE KIDDPYSKIT
     SKDLETGDTT SGDINLVNST KFERKQLVDS EEAGLSLYLL VRELIETFVS VLINLPFTIN
     RIFVHYFTEF LALYTKLAGI LDNINEGSNL STRSKSLQFD LPSQTCIYID MWNIGMRGSL
     NLDLLVNDKR SSSNCGVKNR QSGIYVETDG VSNLYQPKMY EKQTPVHYNL IATKFLSPEI
     RNNHVNDLTM CFDTETGKTD EEFFDEKVAR SIENWGFLNK SCKLDEINWN EWLYSLSRYN
     LPLTAWRNIA PRKWKVCLSE LSSIETNTIT ELKDQVSQNK LHSYYSIYTK KSFLRNKISN
     FSKLRKHRNL LQNLTDSVQN GDVENLSVQR DIMEQRFHCK SCIQKSSRGG RNRISKFVHF
     LSSNVESKNN LNLQIDLLSW LDPDIAKTKI FLKKKKKAKQ LKNPLLRNHY RYRYVLDISG
     RFQKVLNQLN DLTLDEREDA DYIFRWKFKF ETELEKFRNL ISLTRMLGDD QDLITLCTNI
     EVNSDLLNLQ FNAKTKRDMF HNLSVVSAHR LRLVFDDQDL LYKIINPLLK FKGRLRGIFR
     RRLYRNVYNG SYISNLSHIL TERNCKQSCL YNIDDLLSPR RRREFRFLYC LLSPKIEYSQ
     YISRIKKIDN AEKKQTLYHL PRPIRIQKIK RFLWPSHRLE EAACTGRSCV GVMTGSRFVT
     LRIRMYPIPL N