ID   TI214_AMBTC             Reviewed;        1794 AA.
AC   Q70XV6;
DT   28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT   28-NOV-2006, sequence version 2.
DT   25-MAY-2022, entry version 53.
DE   RecName: Full=Protein TIC 214 {ECO:0000250|UniProtKB:P56785};
DE   AltName: Full=Translocon at the inner envelope membrane of chloroplasts 214 {ECO:0000250|UniProtKB:P56785};
DE            Short=AtTIC214 {ECO:0000250|UniProtKB:P56785};
GN   Name=TIC214 {ECO:0000250|UniProtKB:P56785}; Synonyms=ycf1;
OS   Amborella trichopoda.
OG   Plastid; Chloroplast.
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Amborellales; Amborellaceae; Amborella.
OX   NCBI_TaxID=13333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12832641; DOI=10.1093/molbev/msg159;
RA   Goremykin V.V., Hirsch-Ernst K.I., Wolfl S., Hellwig F.H.;
RT   "Analysis of the Amborella trichopoda chloroplast genome sequence suggests
RT   that Amborella is not a basal angiosperm.";
RL   Mol. Biol. Evol. 20:1499-1505(2003).
CC   -!- FUNCTION: Involved in protein precursor import into chloroplasts. May
CC       be part of an intermediate translocation complex acting as a protein-
CC       conducting channel at the inner envelope.
CC       {ECO:0000250|UniProtKB:P56785}.
CC   -!- SUBUNIT: Part of the Tic complex. {ECO:0000250|UniProtKB:P56785}.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast inner membrane
CC       {ECO:0000250|UniProtKB:P56785}; Multi-pass membrane protein
CC       {ECO:0000255}.
CC   -!- SIMILARITY: Belongs to the TIC214 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAD45164.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AJ506156; CAD45164.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; NP_904157.1; NC_005086.1.
DR   AlphaFoldDB; Q70XV6; -.
DR   PRIDE; Q70XV6; -.
DR   GeneID; 2546536; -.
DR   KEGG; atr:2546536; -.
DR   OrthoDB; 53153at2759; -.
DR   Proteomes; UP000017836; Chloroplast.
DR   GO; GO:0009706; C:chloroplast inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR008896; TIC214.
DR   PANTHER; PTHR33163; PTHR33163; 2.
DR   Pfam; PF05758; Ycf1; 2.
PE   3: Inferred from homology;
KW   Chloroplast; Membrane; Plastid; Plastid inner membrane; Protein transport;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..1794
FT                   /note="Protein TIC 214"
FT                   /id="PRO_0000262600"
FT   TRANSMEM        23..43
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        64..84
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        87..107
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        124..144
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        172..192
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        218..238
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          244..307
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        260..307
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1794 AA;  215290 MW;  AAE2E667DB37C3D3 CRC64;
     MILKSFLLGN LLSLCMKIRN SVVVVGLYYG FITTFSIGPS YLFLLRARVM EEGTEKEVSA
     TTGFIMGQFM MLISIYYTPL HLALGRPHTI TVLVLPYLLF HFFWNNHKHF FSYRSTTRNS
     MRNLSIQCVF LNNLIFQLFN HFILPSSTLA RLVNIYMFRC NNKMLFVTSS FVGWLIGHIL
     FMKWVGLVLF WIRQNHSIRS NKYIKYLVSE LRKSMARILS ILLFITCVYY LGRIPSPIFT
     KKLKETSETG ETEEETDVEI ERTSETKGTE QEKEGSTEED PSLFCSEEKG DPDKIDEREG
     VNGKEKTKDH FNLKERWYNN KTVYRDQEDN TAYGDGNQED WELKALKLKE EKKLFWFEKP
     FITFLFDYQR WNRPFRYIEN DQFANTVRNE MSQYFFNTCP SDGKRVISFT YPPSLSVFGE
     MIQKKMSLCG MKELYPKDKN LYNHWVSTNE QKRDKVSKEF INRIEALYGG DIVLQKRVRL
     CNDRDEKECL PKMSDPFLNG SYRGTIKELY SNSIINDPIT STYNSGEKFW INRIHSLLFC
     DLNDQAIRNK SSEIQEIKKK IPQRLYRLTT DLEQDEGEDE RESVEFPEIR SRKTKHMVIY
     ADNEENTNIF THTGAGTTYD PENDQMEEVD VIRYTQKPDF RRDLIKGSMR AQRRKTVTWE
     MLQINLHSPL FLDRIDKNPF FYFDISRIIN LIFRDWTKKK PEFQTSNFKE ETKKEDEIEE
     TWETIAFGQV IRGFLLVTQS ILRKYIVLPS LIIAKNLVRM LLFQLPEWYE DFKEWSREMH
     IKCTYHGVQL SERKFPKNWL KAGIQIKILF PFYLKPWRKS KLRSHHIDHP MKKRKKQNSC
     FLTVWGMETD LPFGPARKGP SFFEPIHKEL EKKFKKGKKK WFLFVRIFKE KKIWVIKRVL
     FIKGVMKELT KANPVFLFGL KRVYDGSENR KDSISNNKTI SESPIRKSPI RTGSMDWTNS
     SLTERKRKDL SDKTTTIRDQ IERIRITRDK KTNFLTIDMN ISPNETSYSD KRSESQKPIW
     QVSKRRSTRL LYKWRYFMKS FIERIHRNVF LCMINLPRIN TQLFLESTKK IIDKYISNDE
     KNQSGIDEKN KKKIHFIFIS TRKLLSTISN KKTNNSKIHC SLSQAYVFYK LSQKPGIKKY
     RLGSLFQYRR AYSIKDRIKD YLEIERIFHS ESKHKKPGNF GMNEWKNWLI GNYQYNFSYT
     RWSRLDPQKW RNKVNEQCMI KNKDSKKTDS YSYEKDPLIN HERHILYSAD LLQNHKKKLS
     KRYRYDLLSY RYINFGNNSS IYRSLLQVNE EQRILILSSH SHIIHKYEQL NLPAISDYLE
     ERFIVDMEKK TDRKYFDLRI IKFWSRRNTN TDMDLRINTN KKNNTGTNYY QMIDKKDLIY
     LTSYQEIYPR NKENNFFDWM GMNEELLYRR ISNLALWFFP ELVLLNDAYK TKPWTIPIRL
     LLFNGKKKIT ETQKMNENKK RDLGILSNQK KYLELGTRDR EEKKWWDQED LRPDTKYQEY
     FGSDVKNQKD VELDVWYREG KSREQEDYTD INKSRKKKQS KSNKEAELDL LLKRYLLFQF
     RWDDSLKKKM INNIKLYSLL LRLMDPKKIV ISSIQRGEMW LDIMLIHKDL PLTKLKKGGV
     FTMEPLRLSR KWNGQFLMYQ TLSISLVHKI KQQTDRRYRE TKYIDENFFD LFIPRNGRVF
     VNGDNKNYDL FVPENISALR RRRELRILSR LNPGKGNINI IFSNRKKIQN CKPFLDRGKH
     LETDTNKAIK FKLFLWPNHR LEDLACMNRY WFDTNNGTRF SMSRIRMYPR FGIS