ID   TI214_ARAHI             Reviewed;        1778 AA.
AC   A4QK78; A4QK66;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   15-MAY-2007, sequence version 1.
DT   25-MAY-2022, entry version 34.
DE   RecName: Full=Protein TIC 214 {ECO:0000250|UniProtKB:P56785};
DE   AltName: Full=Translocon at the inner envelope membrane of chloroplasts 214 {ECO:0000250|UniProtKB:P56785};
DE            Short=AtTIC214 {ECO:0000250|UniProtKB:P56785};
GN   Name=TIC214 {ECO:0000250|UniProtKB:P56785}; Synonyms=ycf1-A;
GN   and
GN   Name=TIC214 {ECO:0000250|UniProtKB:P56785}; Synonyms=ycf1-B;
OS   Arabis hirsuta (Hairy rock-cress) (Turritis hirsuta).
OG   Plastid; Chloroplast.
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Arabideae; Arabis.
OX   NCBI_TaxID=78191;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Hosouchi T., Tsuruoka H., Kotani H.;
RT   "Sequencing analysis of Arabis hirsuta chloroplast DNA.";
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in protein precursor import into chloroplasts. May
CC       be part of an intermediate translocation complex acting as a protein-
CC       conducting channel at the inner envelope.
CC       {ECO:0000250|UniProtKB:P56785}.
CC   -!- SUBUNIT: Part of the Tic complex. {ECO:0000250|UniProtKB:P56785}.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast inner membrane
CC       {ECO:0000250|UniProtKB:P56785}; Multi-pass membrane protein
CC       {ECO:0000255}.
CC   -!- MISCELLANEOUS: There is a partial copy of the N-terminus (positions 1-
CC       341) of ycf1 in the inverted repeat (BAF50071).
CC   -!- SIMILARITY: Belongs to the TIC214 family. {ECO:0000305}.
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DR   EMBL; AP009369; BAF50083.1; -; Genomic_DNA.
DR   EMBL; AP009369; BAF50071.1; -; Genomic_DNA.
DR   RefSeq; YP_001123246.1; NC_009268.1.
DR   RefSeq; YP_001123258.1; NC_009268.1.
DR   AlphaFoldDB; A4QK78; -.
DR   PRIDE; A4QK78; -.
DR   GeneID; 4962573; -.
DR   GeneID; 4962592; -.
DR   GO; GO:0009706; C:chloroplast inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR008896; TIC214.
DR   PANTHER; PTHR33163; PTHR33163; 1.
DR   Pfam; PF05758; Ycf1; 1.
PE   3: Inferred from homology;
KW   Chloroplast; Membrane; Plastid; Plastid inner membrane; Protein transport;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..1778
FT                   /note="Protein TIC 214"
FT                   /id="PRO_0000326561"
FT   TRANSMEM        18..38
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        67..87
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        90..110
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        132..152
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        175..195
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        226..246
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          1498..1520
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1498..1515
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1778 AA;  212663 MW;  C2DD2E48EDB0E2B2 CRC64;
     MVFQSFILGN LVSLCMKIIN SVVVVGLYYG FLTTFSIGPS YLFLLRARVM DEGEEGTEKK
     VSATTGFIAG QLMMFISIYY APLHLALGRP HTITVLALPY LLFHFFWNNN KHFFDYGSTT
     RNEMRNLRIQ CVFLNNLIFQ LFNHFILPSS MLARLVNIYM FRCNNKMLFV TSSFVGWLIG
     HILFMKWVGL VLVWIQQNNS IRSNVLIRSN KYKFLVSELR NSMARIFSIL LFITCVYYLG
     RIPSPIFTKK LKGTSETGGT KQDPEVSTEE APFRSLFSEE REDLDKIDEM EEIRVNGKEK
     INKDDEFHVR TYYNYKTVSE NRDGNKENSN LKFLKIKEDP FFFLWFEKPF VTLVFDYKRW
     NRPNRYIKND KIENTVRNEM SQYFFYTCQS DGKERISFTY PPNLSTFFEM IQKKISSFTR
     AKAPSDQVYA YWSLLNEKKK ENLKNEFLNR IEALDLDKER SFENILEKTT RFCHNETKKE
     YLPKLYDPFL HGISRGKIKK LLPFKKITDI NIGIGGSWIN KIHGILLRIN SHKFEQTIEK
     FTRKSLSIEK KLSFFSEPQE EKINSEEEIK IFKFLFDVVI TDNNNKTLIK NFIDFHEINK
     NVPRWSYKLT SELEELEGEN EENVPTEPGI RSRKAKSVVV FTDKEPHNGI FTNLKDNQNS
     DQKDEMALIR YSQHSDFRRD LIKGSMRSQR RKTVIWDFFQ AKVHSPLFFD RIDKLFFFSF
     DFWGLKKKII RNFMWKKKKK EFLKKEDEQS KRKETRRIEI AETWDSFPFS QIIRGSLLVT
     QSILRKYIIL PLLIIIKNST RALLFQVPEW SEDLKDWKRE MHVKCTYNGV QLSETEFPRN
     WLTDGIQIKI LFPFYLKPWH KLKVQSSQKA RLKKIKDKGE KTDFGFLTVW GMETELPFGS
     AKKKRSFFEP IFKELKKRIK KFKTKPFRVL SIFKERATIF LKVTKERKNW IIKNLLFRKG
     KRKNISKQNI IPLFGVREID ELNETKKDSI MSNQMIYELS GQKKSMEWPN SSLNENKIKN
     LIDRIKIIKN QTEEISKEKE NLTNRCNKPR YDSQIIASSK KRWQAFKRKN IRLIRKSFFF
     FKFCIEQLSI TFFLGIINIP RITTQLQLFF ESTKTILDKY IYKNEENGEK KKNQKNTIYF
     ISTLKNLISK NKKFSYDLCS LSQAYVFYKL SQIQVSNFSK LKAVLEYNIC ITSFFVKNQI
     KDFCQEQGIF HYELKDKTFF NSEVNPWKYW LRSHSQYNLP WIAWARLVTQ KWKKKINQDF
     LVLNTSLIKT DLYEKNKIDN YKKQQFFEAN SLLNSKHNLK KDYIYNSFCY RSIHSREKKF
     DMSMSIGITP DNCLVSSFLE KYNIQVIGEI GHRKYLDWRI LNFWFRKKVN IGLLIDTKSK
     KKYIKTKVQN YKKIDKITKT DLANQKSFFF DWMGMNEERL NHRITNFAFF FFSEFFLFSS
     TYKTKPWVIP IKLLLFNFNE KKNVNKKITL KKKGFIPSNE KGPLRFFNLN KEENELVGQG
     ELESDNEKKR NPESALSNQE KNIEKNYAES KIKKRQNKKQ YKSHTEAELY LFLTRYSRFQ
     LRWNCFFNQK ILNNIKVYCL LVRLKNPNEI AISSIERGEL SLDILMIEKN FTFSKLMKKG
     ILIIEPVRLS VKNDGQLIIY RTVGISLVHK NKQKISKRYK KKSYIDKKNN YDFFIPENIL
     SPKRRREFRI LICFNLKKKN ARDRNSRFDK NIQNLTTVLH KKKDLYKDKK TLIKLKSFLW
     PNFRLEDLAC MNRYWFNTTN GNHFSMIRIH MYARFQIR