TI214_CALFG
ID TI214_CALFG Reviewed; 1828 AA.
AC Q7YJS6;
DT 28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2003, sequence version 1.
DT 25-MAY-2022, entry version 40.
DE RecName: Full=Protein TIC 214 {ECO:0000250|UniProtKB:P56785};
DE AltName: Full=Translocon at the inner envelope membrane of chloroplasts 214 {ECO:0000250|UniProtKB:P56785};
DE Short=AtTIC214 {ECO:0000250|UniProtKB:P56785};
GN Name=TIC214 {ECO:0000250|UniProtKB:P56785}; Synonyms=ycf1;
OS Calycanthus floridus var. glaucus (Eastern sweetshrub) (Calycanthus
OS fertilis var. ferax).
OG Plastid; Chloroplast.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Magnoliidae; Laurales; Calycanthaceae;
OC Calycanthus.
OX NCBI_TaxID=212734;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Goremykin V., Hirsch-Ernst K.I., Woelfl S., Hellwig F.H.;
RT "The chloroplast genome of the 'basal' angiosperm Calycanthus fertilis
RT -- structural and phylogenetic analyses.";
RL Plant Syst. Evol. 242:119-135(2003).
CC -!- FUNCTION: Involved in protein precursor import into chloroplasts. May
CC be part of an intermediate translocation complex acting as a protein-
CC conducting channel at the inner envelope.
CC {ECO:0000250|UniProtKB:P56785}.
CC -!- SUBUNIT: Part of the Tic complex. {ECO:0000250|UniProtKB:P56785}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast inner membrane
CC {ECO:0000250|UniProtKB:P56785}; Multi-pass membrane protein
CC {ECO:0000255}.
CC -!- SIMILARITY: Belongs to the TIC214 family. {ECO:0000305}.
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DR EMBL; AJ428413; CAD28780.1; -; Genomic_DNA.
DR RefSeq; NP_862813.1; NC_004993.1.
DR AlphaFoldDB; Q7YJS6; -.
DR PRIDE; Q7YJS6; -.
DR GeneID; 2598087; -.
DR GO; GO:0009706; C:chloroplast inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR InterPro; IPR008896; TIC214.
DR PANTHER; PTHR33163; PTHR33163; 1.
DR Pfam; PF05758; Ycf1; 2.
PE 3: Inferred from homology;
KW Chloroplast; Membrane; Plastid; Plastid inner membrane; Protein transport;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..1828
FT /note="Protein TIC 214"
FT /id="PRO_0000262602"
FT TRANSMEM 18..38
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 64..84
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 87..107
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 124..144
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 172..192
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 222..242
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 270..301
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 618..637
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 741..763
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1533..1571
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 620..637
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 742..763
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1548..1562
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1828 AA; 217554 MW; A8B73F2E1680BD6C CRC64;
MILKSFLLGN LLSLCMKIIN SVVVVGLYYG FLTTFSIGPS YLFLLRARVM EEGTEKEVSA
TTGFITGQLM IFISIYYAPL HLAMGRPYTI TVLGLPYLLF HFFWKNHKHF FDYGSTNLNS
MRNFSIQSIF LNNFIFQLLN HFVLPSSTLI RLVNISMFRC NNKTLFVISS FVGWLIGHIL
FMKWVGLILF WIQRNRSIRS NPLIRSNKYL VSELRNFLSR MVNIFLFITC VYYLGRIPSP
ILTKKLKETS ETEEGEENED ETNVEIEKFS EAKETKQEQK GSFAEEDSSL GSEEREDPNK
LYGKKRKGYQ ENWKFEILKD KDLFWFEKPI VTLLFDYKRW DRPLRYIKND RFANAVRNEM
SQYFFHKCPV DGKQKISFTY PPSLSIFFEM IEKHLSLCTT EKLSPEDLYN HWVYTNEKKR
CNLNNEFINR IEALNKGSLS MHVLEKRTRL YNDKNEQECL PRMYDPFLNG PYRGTIKKVY
SHSILDASTT STEDSLRVVW INKIDDILPT NYQEFEEKMD PFNGESLSTD INHSLASTSE
LAGESPMDFR FNLKEGLVLP AEQKQRRFDS ENPMKYLKFL FDAITTDTPN YKTIQTKSIG
IEEIGKKVPR WSYKLTNDLQ QQERENEEES TEDHAIRSRK SKRVVIYTDN DKNPNTPIST
NGNQAEEVAL IRYSQQSDFR RDLIKGSRRA QRRKTVTWEI FQANVHSPLF LDRIDKTFFF
SFDISGTINL AFRNWTEKGS EFKTSNSDEK ETKEKEKKRE DKKEENERIA IAETWDTIIF
AQAIRGIMLV TQSILRKYIV LPSLIIAKNL VRMLLFQFPE WYEDLKEWNR EMHVKCTYNG
VQLSETEFPK DWLTDGIQIK ILFPFCLKPW HRSKLRPHHR DPMKKKGKKD NFCFLTVWGM
ETELPFGSSR KRPSFFEPIL KELEKKIRKA KKKYFLVLSV LKEWFRKVSK EKTRWIRKIV
LFIKKIIKEF AKVNSILLFG RKKVYESNEN KKDSITIISN KILSEPTIRI RSMDWTNYSL
TEKKMKDLAD RTTTIRNQIE RITKEKRTIF LTPDRNGSPN ETSCDDKRSE SQKHIWQISK
RRSAWFIRKW RYFIKIFSER IYIDIFLCAI NIPRVNAQLF FESTKKILDK YIYNDQRKKE
GIDETNPNKL ISISKKYFSN ISNKKSRIYW DLSSLSQAYL FYKLSQTQVI NKYRLKSVLQ
YRDLFLRDRI RDYLGTRGIF DSKFKKLPNS GMGEWKNWLR GHYQYNLSQT RWSRLVSKKW
RDRVNQHRTI QNKDYKRDSY EKDQFIHYEK QNDSVVNSLP SQKEKFQKHY RYDLFSYKYI
NYGVNYGDSK DSYRSPLQVN EDRGIPYNYN TPKSESVFVL GGIALSDYLE EKYIIDRGKS
RDKKYLEWKI LNFCLRKNID IEAWTNINKN TKIGTNDYQI IDKKNPFYLT TYQEINPLNP
KSFFFGRMGM NQGMLYRPIA NLEPWFFSEF VPLYDAYKIK PWIIPIKLLL FNFEGNETIS
ENKNINGNKK GELPISSNQK DYLELENRNQ EEKEEFGQGN LGSDTQNQQK DVEKDYAKSD
IKKRGKKRQS KSNKGAELQF FLKRYLLFQL RWDDPLNQRM MNNVKVYCLL LRLINPREIA
ISSIQRGEMR LDVMLIQKDL TLTELIKRGI LIIEPVRLSI KWDGQFIMYQ TIGISLVHKN
KHQTNRRYRE KRYVDENYFD GSIAQHGKML VNRAENDYDL LVPENILSPR RRRELRILIS
FNSGNRNVVD RNLVFFNGNN VKNFGQFLDE DKHIDTDINK FIQFKLFLWP NYRLEDLACI
NRYWFDTNNG SRFSMLRIHM YPPRFGIG
