ID   TI214_CAPBU             Reviewed;        1789 AA.
AC   A4QKQ3; A4QKP1;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   15-MAY-2007, sequence version 1.
DT   25-MAY-2022, entry version 37.
DE   RecName: Full=Protein TIC 214 {ECO:0000250|UniProtKB:P56785};
DE   AltName: Full=Translocon at the inner envelope membrane of chloroplasts 214 {ECO:0000250|UniProtKB:P56785};
DE            Short=AtTIC214 {ECO:0000250|UniProtKB:P56785};
GN   Name=TIC214 {ECO:0000250|UniProtKB:P56785}; Synonyms=ycf1-A;
GN   and
GN   Name=TIC214 {ECO:0000250|UniProtKB:P56785}; Synonyms=ycf1-B;
OS   Capsella bursa-pastoris (Shepherd's purse) (Thlaspi bursa-pastoris).
OG   Plastid; Chloroplast.
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Capsella.
OX   NCBI_TaxID=3719;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Hosouchi T., Tsuruoka H., Kotani H.;
RT   "Sequencing analysis of Capsella bursa-pastoris JO22 chloroplast DNA.";
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in protein precursor import into chloroplasts. May
CC       be part of an intermediate translocation complex acting as a protein-
CC       conducting channel at the inner envelope.
CC       {ECO:0000250|UniProtKB:P56785}.
CC   -!- SUBUNIT: Part of the Tic complex. {ECO:0000250|UniProtKB:P56785}.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast inner membrane
CC       {ECO:0000250|UniProtKB:P56785}; Multi-pass membrane protein
CC       {ECO:0000255}.
CC   -!- MISCELLANEOUS: There is a partial copy of the N-terminus (positions 1-
CC       341) of ycf1 in the inverted repeat (BAF50246).
CC   -!- SIMILARITY: Belongs to the TIC214 family. {ECO:0000305}.
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DR   EMBL; AP009371; BAF50258.1; -; Genomic_DNA.
DR   EMBL; AP009371; BAF50246.1; -; Genomic_DNA.
DR   RefSeq; YP_001123421.1; NC_009270.1.
DR   RefSeq; YP_001123433.1; NC_009270.1.
DR   AlphaFoldDB; A4QKQ3; -.
DR   PRIDE; A4QKQ3; -.
DR   GeneID; 4961678; -.
DR   GeneID; 4961721; -.
DR   GO; GO:0009706; C:chloroplast inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR008896; TIC214.
DR   PANTHER; PTHR33163; PTHR33163; 1.
DR   Pfam; PF05758; Ycf1; 1.
PE   3: Inferred from homology;
KW   Chloroplast; Membrane; Plastid; Plastid inner membrane; Protein transport;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..1789
FT                   /note="Protein TIC 214"
FT                   /id="PRO_0000326564"
FT   TRANSMEM        19..39
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        68..88
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        91..111
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        133..153
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        176..196
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        227..247
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   CONFLICT        341
FT                   /note="H -> Q (in Ref. 1; BAF50246)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   1789 AA;  214119 MW;  7C1A50A53BB6404F CRC64;
     MMVFQSFILG NLVSLCMKII NSVVVVGLYY GFLTTFSIGP SYLFLLRARV MDEGEEGTEK
     KVSATTGFIA GQLMMFISIY YAPLHLALGR PHTITVLALP YLLFHFFWNN HKHFFDYGST
     TRNEMRNLRI QCVFLNNLIF QLFNHFILPS SMLARLVNIY MFRCNNKMLF VTSSFVGWLI
     GHILFMKWVG LVLVWIQQNN SIRSNVLIRS NKYKFLVSEL RNSMARIFSI LLFITCVYYL
     GRIPSPIFTK KLKGTSETGG TKQDQEVSTA EAPFPSLFSE EGEDLDKIDE MEEIRVNEKD
     KINKDDEFHV RTYYKTVSEN LDGNKENSNL EFFKIKKKED HFLWFEKPFV TLVFDYKRWN
     RPNRYIKNDK IENTVRNEMA QYFFYTCQSD GKERIAFTYP PNLSTFFEMI QKRIPSFTRE
     KITSDQVSTY WSLIHEEKKE NLKKEFLNRI EALDKGGSVE NILEKTTRFC YNEAKKEYLP
     KIYDPFLHGI SRGRIKKLPP FKIITETYRK NNIRGSWINK IHGLLLKLNY HKFEQTIENF
     NRKSLSIEKK LSFFSEPQQE EKFNSEEEIK IFKFLFDIVR TDSNDQTLIK NFIDFHEINK
     KVPRWSYKLI SELEELEGEN EENVPMEPGI RSRKAKRVVV FTDKEPHDEI YTNLKENQNS
     DQKDEMALIR YSQQSDFRRE IIKGSMRSQR RKPVIWEFFQ AKVHSPLFFD RIDKLFFFSF
     DIWGLKKKIL KNFISQTKKK NFDKKEEEQS KIEEKRRIEI AETWDSFLFA QIIRGSLLVT
     QSILRKYIIL PLLILIKNSV RMLLFQFPEW SEDLKDWKRE MHVKCTYNGV QLSETEFPRN
     WLTDGIQIKI LFPFYLKPWH KSKFQASQKA RLKKTKDKGE KNDFCFLTVW GMETELPFGS
     AQRKPSFFEP ISKELKKRIK KLKTKSLVVL RIFKERATIF LKVANEIKNW ILKNFIFIKG
     KIKDLSKRNP ISLFGPREIY ELNETKKDSI IRNQIIHELS VQNKSMEWTN SSLSENKITN
     LIDRIKTIRN QIEEISKEKQ NLTNNCTKLR YDSKKIESSK KIWQAFKRKN TRLIRKSIFF
     FKFCIEQLSI AIFLGIINIP KITTQLFFES IKTILDKSIY KNEEKGEKKK NPFYFISTIK
     NLISNKKKMS YDLCSLSQAY VFYKLSQIKV SNVSKLKDVL EYNICITSFF VKNKIKSFFQ
     EQGIFHYELK NKTFLNSEVN QWKNWLRSHY QYNLPQIAWA RLVTQNWKKK INKDSLVLNP
     SLTKEDSYEK KKFDNYKKQN FFEADSVLNP KHNFKKDYIY NLFCYKSIHP TENFFDMYVG
     IALDNCLVSS CLEKYNIRGM REIWHRKYVD WRILNFWFTK KVNIEPWVNT KSKKKYINTK
     VQNYQRIDKI TKTDLANQKS FFFDWMGMNE EILNHRITNF EFFFFPEFFL FSSTYKIKPW
     VIPIKLLLLN FNENINVNKK LTRKKKGFIP SNEKKSLRFY NLNKEEKESA GQFELESDKE
     KKRNPESALL NQEKNIEENF AESMIKKRQN KKQYKSNTEA ELDLFLTRYS RFQLRWNCFF
     NQKILNNVKV YCLLVRLNNP NEIAISSIER GEMSLDILMI EKNFTFAKLM KKGILIIEPV
     RLSVQNDGQL IIYRTIGIPL VHKNKHKISK RSKKKSYIDK KIFEKSKTKY QNKTVNRKKK
     HYDFFVPENI LSPKRRREFR ILICFNLKKK TARDRNSRFD KNIQNLTTVL HKKKDLNKEK
     NNLINLKSFL WPKFRLEDLA CMNRYWFNTT NGTNFSMIRI RMYTRFPIH