ID   TI214_CERDE             Reviewed;        1899 AA.
AC   A8SEG5;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   15-JAN-2008, sequence version 1.
DT   25-MAY-2022, entry version 28.
DE   RecName: Full=Protein TIC 214 {ECO:0000250|UniProtKB:P56785};
DE   AltName: Full=Translocon at the inner envelope membrane of chloroplasts 214 {ECO:0000250|UniProtKB:P56785};
DE            Short=AtTIC214 {ECO:0000250|UniProtKB:P56785};
GN   Name=TIC214 {ECO:0000250|UniProtKB:P56785}; Synonyms=ycf1;
OS   Ceratophyllum demersum (Rigid hornwort) (Coontail).
OG   Plastid; Chloroplast.
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Ceratophyllales; Ceratophyllaceae;
OC   Ceratophyllum.
OX   NCBI_TaxID=4428;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=18048334; DOI=10.1073/pnas.0708072104;
RA   Moore M.J., Bell C.D., Soltis P.S., Soltis D.E.;
RT   "Using plastid genome-scale data to resolve enigmatic relationships among
RT   basal angiosperms.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:19363-19368(2007).
CC   -!- FUNCTION: Involved in protein precursor import into chloroplasts. May
CC       be part of an intermediate translocation complex acting as a protein-
CC       conducting channel at the inner envelope.
CC       {ECO:0000250|UniProtKB:P56785}.
CC   -!- SUBUNIT: Part of the Tic complex. {ECO:0000250|UniProtKB:P56785}.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast inner membrane
CC       {ECO:0000250|UniProtKB:P56785}; Multi-pass membrane protein
CC       {ECO:0000255}.
CC   -!- SIMILARITY: Belongs to the TIC214 family. {ECO:0000305}.
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DR   EMBL; EF614270; ABQ81509.1; -; Genomic_DNA.
DR   RefSeq; YP_001542505.1; NC_009962.1.
DR   AlphaFoldDB; A8SEG5; -.
DR   PRIDE; A8SEG5; -.
DR   GeneID; 5729460; -.
DR   GO; GO:0009706; C:chloroplast inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR008896; TIC214.
DR   PANTHER; PTHR33163; PTHR33163; 1.
DR   Pfam; PF05758; Ycf1; 1.
PE   3: Inferred from homology;
KW   Chloroplast; Membrane; Plastid; Plastid inner membrane; Protein transport;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..1899
FT                   /note="Protein TIC 214"
FT                   /id="PRO_0000326565"
FT   TRANSMEM        23..43
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        64..84
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        87..107
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        124..144
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        172..192
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        217..237
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          256..280
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1581..1619
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1581..1601
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1602..1619
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1899 AA;  225214 MW;  D2826D993FBA0D98 CRC64;
     MILKSFILGN LVSLCMKIIN SAVVVGLYYG FLTTFSIGPS YLFLLRARVM EEGTEKEVSA
     TTGFITGQLM MFISIYYVPL HLALVRPHTI TVLVLPYLLF HFFWNNHKNF FDYGYTTRNS
     MRNLSIQCLF LNNLIVQFLN LFILPSSTLS RLVNISLFRC NNKMLFVTSS FVGWLIGHIL
     FMKLVGLVLV CIRQNLATRS NRLLHSNMYL VSEFRNWTAR IFSTLLFITC MYYLGVHRVK
     LPILTNRLKK TSEIAEQKKS KEETDEEIEK TFETKETKKE QQEFTDKVHS LYFEEQEDPI
     EEQGYPYKRN ETKEKRLGKE KTKDEFHKNI PKYETLDLDR NQEKKLELTI LKQKTNLVWF
     EKPLVTLLFD VKRWDRPLRH IKNSRFENTI KQEMAQYFFH TCTSDGKQKI SFTYPPSLST
     FFEMMQRKIS LCTIEKQSPE NMYNHWLYTN EQKRHNLSNE FLNRIEILDK GSSALDVLEQ
     KNRLSNDENK QECLPKMYDP FLSGPSRGRI KKGYSTRRIM NDSSASTKGK KVWINKIHGI
     FPIDYVQLEH KIDTFLDESL SGESGTSFPG ESAPLKGLSL STDKKRIDSE NQEKSLKFLF
     DVVTTNPNTQ TRDKESILIR EIHKRVPQWS YKLIRDLEEE EKETEEEPKQ VFGIRLRKGK
     RVVIYTDTND KTNTDTSTST PSNPAEEIAL IRYSHQPDFR RNLIKGSIRS QRRKTVVWEL
     FQTNLHSPLF LDRIDKTFSF DIYRIMDLFF RSWMWKEPEL KTSKSESEVE EKEEKVKKQK
     EKKDENERIA IAEAWDTFIV TQAVRGLMLV TQSIFRKYIV LPSLIIVKNI GRMLLFQFPE
     WSEDFKDWKR EMHVKCTYNG VQLSETEFPK HWLTDGIQIK ILFPFCLKPW HESKLRSHHI
     THEHEMDAMK KKGKEQNFCF LTVWGMEAEL PFGYARKRPS FFEPIFKELT KKIQKVKKIC
     FLVLRTFKEG AKGLVKVLKE KASWVIKIVL FIKKKIKELA KIFFFGFGLR EVEVEVYESN
     ENGKDSITNN NIINELPIRI RSVNWTNDSL TEKKIKDLAD RTTTIQNEIE RIKKEKKILF
     MTPDKNVSPN KLSCNDKRSE SQKFFWQISK RKGARLIRKW HYFFKSFIER IYIGIFLCTI
     YIPKINAKLF LESKKNLQKF FDKSIYNNET NPDGIDETNK NAVHFISTLK KALFNISDKN
     SSISCDLSYL SQAYVFYKLS QTQVINKYDL RYVFQYQGAH SFLKDRIKDY LQTRGIFHSE
     SRQNPFRNSE INDWKNWLRG HYQYNLSQTR WSRLVPQQWK NRVNQRHRIQ KKDSQKWHSY
     EQDQLIHYKT KKNYAVHSLP MQKEKLKKHY RYDLLSHKYL NFEDRNNSYI YGSPLQVNGD
     REITYNYKTH KSKSFCTLGG LTISDYLKEE YLIDTDKNSD RKYFDLGIIY FSLRKNIDIK
     AWIDKNIGTN TNININKKIK TGNTFYQISD KKNLFDLTIS QQRNSSNQKT KKTKKFGFLD
     WMGMNKQMLD HSISNFEPSW FLPEFCLLYD AYKVKPWIMP TKLLLLNLDT NENIRNQNEN
     IRKSNKINGN KKQDFRISSN PKDYLELDNG TPKEKEKQGK VKGNLGSNQK TRENLGLDLR
     NQQKNVENDY VGSDIKKRRK KKQFNNNKET ELDSILTNYL VFQLRWNPFL NKGIMKNIKV
     DCLLLRLINP KEIAIDSIQS GEMHLDLMSI QRDPSLTKLI KDGIFVIEPR RLSIKRDGQF
     IKYQTIGISL VHKRKYQTNR GYPENKYIDE NDFYGSISQH GKMFVNGDEN HYDLIVPENI
     LSTRRRRELR IRNCLNSGNT ENRNPVFFDS TNVRNCGKFL DEDKYLDTDI QKLIKFKLFL
     WPNFRLEDLA CINRYWFDTN NGSRFSMLRI HMYPRFIVS