TI214_CHLSC
ID TI214_CHLSC Reviewed; 1877 AA.
AC A6MMG9; A6MMI1;
DT 08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 24-JUL-2007, sequence version 1.
DT 25-MAY-2022, entry version 35.
DE RecName: Full=Protein TIC 214 {ECO:0000250|UniProtKB:P56785};
DE AltName: Full=Translocon at the inner envelope membrane of chloroplasts 214 {ECO:0000250|UniProtKB:P56785};
DE Short=AtTIC214 {ECO:0000250|UniProtKB:P56785};
GN Name=TIC214 {ECO:0000250|UniProtKB:P56785}; Synonyms=ycf1-A;
GN and
GN Name=TIC214 {ECO:0000250|UniProtKB:P56785}; Synonyms=ycf1-B;
OS Chloranthus spicatus (Chulantree) (Nigrina spicata).
OG Plastid; Chloroplast.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Chloranthales; Chloranthaceae; Chloranthus.
OX NCBI_TaxID=13006;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=17644003; DOI=10.1016/j.ympev.2007.06.004;
RA Hansen D.R., Dastidar S.G., Cai Z., Penaflor C., Kuehl J.V., Boore J.L.,
RA Jansen R.K.;
RT "Phylogenetic and evolutionary implications of complete chloroplast genome
RT sequences of four early-diverging angiosperms: Buxus (Buxaceae),
RT Chloranthus (Chloranthaceae), Dioscorea (Dioscoreaceae), and Illicium
RT (Schisandraceae).";
RL Mol. Phylogenet. Evol. 45:547-563(2007).
CC -!- FUNCTION: Involved in protein precursor import into chloroplasts. May
CC be part of an intermediate translocation complex acting as a protein-
CC conducting channel at the inner envelope.
CC {ECO:0000250|UniProtKB:P56785}.
CC -!- SUBUNIT: Part of the Tic complex. {ECO:0000250|UniProtKB:P56785}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast inner membrane
CC {ECO:0000250|UniProtKB:P56785}; Multi-pass membrane protein
CC {ECO:0000255}.
CC -!- MISCELLANEOUS: There is a partial copy of the N-terminus (positions 1-
CC 454) of ycf1 in the inverted repeat (ABQ43318).
CC -!- SIMILARITY: Belongs to the TIC214 family. {ECO:0000305}.
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DR EMBL; EF380352; ABQ43306.1; -; Genomic_DNA.
DR EMBL; EF380352; ABQ43318.1; -; Genomic_DNA.
DR RefSeq; YP_001294145.1; NC_009598.1.
DR RefSeq; YP_001294157.1; NC_009598.1.
DR AlphaFoldDB; A6MMG9; -.
DR PRIDE; A6MMG9; -.
DR GeneID; 5236523; -.
DR GeneID; 5236525; -.
DR GO; GO:0009706; C:chloroplast inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR InterPro; IPR008896; TIC214.
DR PANTHER; PTHR33163; PTHR33163; 1.
DR Pfam; PF05758; Ycf1; 1.
PE 3: Inferred from homology;
KW Chloroplast; Membrane; Plastid; Plastid inner membrane; Protein transport;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..1877
FT /note="Protein TIC 214"
FT /id="PRO_0000326566"
FT TRANSMEM 18..38
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 64..84
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 87..107
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 124..144
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 172..192
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 221..241
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 246..313
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 644..695
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 774..795
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 267..313
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 659..695
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 448..454
FT /note="LNNEFIN -> KKIIIII (in Ref. 1; ABQ43318)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 1877 AA; 222822 MW; 7DEC614D23A13483 CRC64;
MILKSFLLGN LLSLCMKIIN SVVVVGLYYG FLTTFSVGPS YLFLLRARVM EEGTEKEVSA
TTGFITGQLM MFISIYYAPL HLALGRPHTI TVLVLPYLLF HFFWKNHKHF FDYGSTTRNS
MRNLSIQCVF LNNLIFQLFN HFILPSSTLA RLVNIYMFRC NNKMLFVTSS FVGWLIGHIL
FMKWVGLVLF WIRQNNSIRS NVLIRSNKYL VSELRNSMAR IFRILLFITC VYYLGRIPSP
IVTKKLKETS ETEEGGESEE ETDVEIETTS ETRGTQKEQE GSTEEDPSLC SEEKEDPDKI
DETEEIRVNG KEKTKDEFHK HRPVYENSYL DGKKKIENWE LGILKEDKDL FWFEKPLLTL
LFDYKRWNRP LRYIKNDRFE NAVRNEMSQY FFHTCPSDGK QIISFTYPPS LSTFLEMIQK
KMSLCTTKPE PEDLYNNWIY INDQKINLNN EFINRIEALD RGSLAMDILE KRTRLCNDEN
EQEYLLEMYD PLLNGPYRGT IKKCNSRSIK DDSITPTEDS IKRIWINNIY GILSTDYREF
EHKIDLFDRE SLSTDIGHSL TLIIGHSLPA ISKFAGESEP SLNFKRLALL AEQRRIDSEN
KEKCLQLLSE ENTTHPNDQT IRNQSIGIEE IGKRVPRWSY KLTDDFEEQE EEDEEESTED
HEIRSRKAKR VVIYTDNDEN TDTDTSTKDT TNSDRAEEVA LIRYSQQSDF RRNLIKGSMR
AQRRKTVTWE MFQANVHSPL FLNRIDRTSP FFSFDFDIAQ IMKPLLRNWM ENEPEFKTSD
SEEKEAKEEE KQKKEKQEAD ERIFIAEIWD TIIFAQAIRG SMLVTQSILR KYIVLPSLII
AKNIGRMLLF QFPEWYEDLK GWNKEMHIKC TYNGVQLSET EFPKDWLTDG IQIKILFPFC
LKPWRRSKLK LRSHHEDPLT LKKKGKKENF CFLTIWGMET ELPFGSPRKQ PSFFEPISKE
LEKIIRKVKR KFFLVLRVFK ERTKWFLKLS KEKAKWVVLF IKRILKEFEK VNPISLFGLM
KVHEPSEKGK DCIISNKIAH ESPIQIRSMD WTNYSLTEQK MKDLANRITT IRNQIEKITK
EKKKRFLTPD INISPNEIGC DDKRSESQKH IWQISKRRSA KLIRNWPYLM KSFIERIYID
IFLCTINIPI INAQLLLEST KKIIDKYIYN DETNQEGIDE TNLNIIHFIS TIKKSLSNTN
ISNKNLQIYC DLSSLSQAYV FYKLSKIKVI NLYRLGSALQ YHETYLFLKD RIKDYCGTQG
IFDSESRHKK PQNSGMNEWK NWLRGHYQYK LSQTKWSRLV PRKWRNRVNQ RRMIPNKDSK
KWNSYEKEKD QLIHYDKKND SAVDSLPSQK EKFKKHSRYD LLSHKYIIYE DGKDSSIYGS
LLQVNRNQEI PYNYKTHKPK PFYVPGGIAI SDYLGEEYII DIDTDQNPDR KYFDWGILRF
CFRKNNINIE PWTDMDSGTN NYQITDKKDL FSLTIHQEIN PSTSNSNQKK NFFDWMGMNE
EMLSRPISNL EPWFFPEFVL LSDAYKVNPR TIPIKLLLFN FHENENIQNE NISENKNING
NKKKDFRISS NQKEYLDQNH EEKELLGQED CGSDPRNQQK YIEEDYTGSD IKKRRSRKKK
LSKSNEEVEL DFFLKRYLFF QLRWDYSLDQ RIINNIKIYC LLLRLINPNE IAISSIQKGE
MFLDVMAIQK DLAFTELRKK GIFIIEPLRL SIKWDGPFYM YQTVGISLVH KSKHQINRRY
REKRYVDQNH FNRSTAQHGK ILVNGDENHY DLLFPEKIPS TRRRKEMRIL ISFNSGNGNV
VNRNPVFLNG NNVRNCSQFF DEDKHFDTNK FMKFKFFLWP NYRLEDLACM NRYWFDTNNG
SRFSMLRIHM YPRFIIS
