TI214_CITSI
ID TI214_CITSI Reviewed; 1829 AA.
AC Q09MB8; Q09MD0;
DT 28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT 17-OCT-2006, sequence version 1.
DT 25-MAY-2022, entry version 37.
DE RecName: Full=Protein TIC 214 {ECO:0000250|UniProtKB:P56785};
DE AltName: Full=Translocon at the inner envelope membrane of chloroplasts 214 {ECO:0000250|UniProtKB:P56785};
DE Short=AtTIC214 {ECO:0000250|UniProtKB:P56785};
GN Name=TIC214 {ECO:0000250|UniProtKB:P56785}; Synonyms=ycf1-A;
GN and
GN Name=TIC214 {ECO:0000250|UniProtKB:P56785}; Synonyms=ycf1-B;
OS Citrus sinensis (Sweet orange) (Citrus aurantium var. sinensis).
OG Plastid; Chloroplast.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Sapindales; Rutaceae; Aurantioideae; Citrus.
OX NCBI_TaxID=2711;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Osbeck var. Ridge Pineapple;
RX PubMed=17010212; DOI=10.1186/1471-2229-6-21;
RA Bausher M.G., Singh N.D., Lee S.-B., Jansen R.K., Daniell H.;
RT "The complete chloroplast genome sequence of Citrus sinensis (L.) Osbeck
RT var 'Ridge Pineapple': organization and phylogenetic relationships to other
RT angiosperms.";
RL BMC Plant Biol. 6:21-21(2006).
CC -!- FUNCTION: Involved in protein precursor import into chloroplasts. May
CC be part of an intermediate translocation complex acting as a protein-
CC conducting channel at the inner envelope.
CC {ECO:0000250|UniProtKB:P56785}.
CC -!- SUBUNIT: Part of the Tic complex. {ECO:0000250|UniProtKB:P56785}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast inner membrane
CC {ECO:0000250|UniProtKB:P56785}; Multi-pass membrane protein
CC {ECO:0000255}.
CC -!- MISCELLANEOUS: There is a partial copy of the N-terminus (positions 1-
CC 363) of ycf1 in the inverted repeat (ABI49067).
CC -!- SIMILARITY: Belongs to the TIC214 family. {ECO:0000305}.
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DR EMBL; DQ864733; ABI49067.1; -; Genomic_DNA.
DR EMBL; DQ864733; ABI49079.1; -; Genomic_DNA.
DR RefSeq; YP_740523.1; NC_008334.1.
DR RefSeq; YP_740535.1; NC_008334.1.
DR AlphaFoldDB; Q09MB8; -.
DR PRIDE; Q09MB8; -.
DR GeneID; 4271109; -.
DR GeneID; 4271147; -.
DR KEGG; cit:4271109; -.
DR KEGG; cit:4271147; -.
DR OrthoDB; 53153at2759; -.
DR GO; GO:0009706; C:chloroplast inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR InterPro; IPR008896; TIC214.
DR PANTHER; PTHR33163; PTHR33163; 2.
DR Pfam; PF05758; Ycf1; 1.
PE 3: Inferred from homology;
KW Chloroplast; Membrane; Plastid; Plastid inner membrane; Protein transport;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..1829
FT /note="Protein TIC 214"
FT /id="PRO_0000262604"
FT TRANSMEM 18..38
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 67..87
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 90..110
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 127..147
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 174..194
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 224..244
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 260..301
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 287..301
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1829 AA; 217535 MW; E3C12A8FB110BE0E CRC64;
MIFQSFILGN LVSLCMKIIN SVVVVGLYYG FMTTFSIGPS YLFLLRARVM EEGEEGTEKK
VSATTGFIAG QLMMFISIYY APLHLALGRP HTITVLALPY LLFHFFWNNP KHFFDYGSTT
RNSMRNLSIQ CVFLNNLIFQ LFNHFLLPSS MLARLVNIYM FRCNNKMLFV TSSFVGWLIG
HILFMKWVGL VLVWMQQKNS IRSNVLIRFN KYLVSELRNS MARIFSILLF ITCIYYLGRI
PSPIFTKKLK VKETSETEER DVEIEKTFER GGTKQGQEVS AEEDPSPSLF SEEKEDPDKI
EETEEIRVNG KEKKKTKHEF HLRFKETCDK NSPVYETSYL DGNQENSKFE IFQLFKEKKE
EKYLLWFEKP LVTLLFDYKR WTRPLRYKKN NRFENAVRNE MSHYFFYACR SDGKERISFT
YPASLSTFLD MIKKNNYFFA TEKLSSDEFS THWNYTNNQK IKNLSKEFRN RLEGLDKGSL
IRDILEKRTQ LCNDKTKKKY LPKTYDPLLN GPYRGRIKKF FSPPILNTTY IKNKIRTPWI
NKIHNLIFIN DYHEFEQTID RFNRKSFSSE EVRSLLTERE REHIDSEDRI KSLNFLFDAV
ITDPNDQKIR KKAIKEISKR VPRWSYKLID NVYQELGEYD ENVRGKHAFR SRKAKRLVVA
VDHQTKGDVS LPHYLEQSDF RRYIIKGSMR AQRRKTVIWK PVQANAHSPL FLDRIDKTLY
LSFDISQLMK VILRNWMVKN KNQKLSDYTN AKTRKLDKKE KKKLKGERYQ RQEMVRIKQA
EGWDKRLLTR ILRSSMLVIQ SILRKYIVLP LLIIAKNVVR ILLFQDPEWS EDFKDWNREI
YVKCTYSGVN LSETEFPKNW LIEGIQIKIL FPFHLKPWHG STIQSSHKDP KSEQETDVCF
LTIFGLETDM PFGSPQKRRS FFEPIFKELK KKIRKLKTKS FIVLRDFKEG KIKELSKINL
REIEKLRETQ KNSIISKQMI HEPSIEISSM DWTKLSRTEK KMKDLTNRTS RIRNQIYKIT
KEKKKGSLTQ ETNISSNKPT YSVKILDPSK RIWRILKKRN ARLIRKSYLF LKFGIEKIYR
NIFISTLTIP RINTKPFRES TRKQMKIIEK NIHNNEANPE RINKTNKNRI ISTIQKLISK
TSNKNSKISC NLLSFSQSQA YVFYKLLQVP ILNFYNLRPV LQYHGTSLFL KNEIKDFFEK
HGIFNYQLRH KPLWNFGRNT RKHCLSGHYQ YDLSRIKWAR LVPQEWRNRA NQHCMAQNKD
LIKRDSYEKN GLTHYEKQHF FEADLLRNQK SNFKKHYRYD LLSYKSLNYE DKKDSYIDRS
LVQVNNKEEY YSNYNRKKVK LLAMLGSISI NNYIGEDDIM DMEKFLYRKY FDWRILNFCL
RNKANMEAWV DMDTGTSSNQ NTRIGSNNYQ KINAINNRVP FYLTIHQDEE INPSTQKGFF
CDWMGMNEEI LSCPISNPES WFFPEFVLLF NAYRTKPWII PIKLLLFNFN GNSKKNRTGK
KEADLFISPT QKEYFELSNQ SKEENELADQ GTPRSDAQKQ VILGSVLSNQ EKDGEENYTG
SDMKTRIKKK QSKRETEVQL DFFLKRYLCL QLRWRGAVSF REKILNDMQV YCHLVRLINP
SDVAIASIQR GEMSLPILIT KKKFALKELT KGGMLIIEPR RLSVKNDGQF FLYQIVGIAL
VHKNKRKITK RYQEKGYVDK KDFDEFIAKH QKMTGNRNKN HYDLLVPETI LLPKRRRELR
TLICFNSKNQ NGMQKNPVFF NNGKGGGRVL DKNKNLAREK NQLIQLKFFI WANSRLEDLI
CMNRYWFNTN NGSRFSMVRV HMYPRLKIR
