TI214_CRUWA
ID TI214_CRUWA Reviewed; 1795 AA.
AC A4QKZ2; A4QKY0;
DT 08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 15-MAY-2007, sequence version 1.
DT 25-MAY-2022, entry version 35.
DE RecName: Full=Protein TIC 214 {ECO:0000250|UniProtKB:P56785};
DE AltName: Full=Translocon at the inner envelope membrane of chloroplasts 214 {ECO:0000250|UniProtKB:P56785};
DE Short=AtTIC214 {ECO:0000250|UniProtKB:P56785};
GN Name=TIC214 {ECO:0000250|UniProtKB:P56785}; Synonyms=ycf1-A;
GN and
GN Name=TIC214 {ECO:0000250|UniProtKB:P56785}; Synonyms=ycf1-B;
OS Crucihimalaya wallichii (Rock-cress) (Arabidopsis campestris).
OG Plastid; Chloroplast.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Crucihimalayeae; Crucihimalaya.
OX NCBI_TaxID=78192;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Hosouchi T., Tsuruoka H., Kotani H.;
RT "Sequencing analysis of Crucihimalaya wallichii chloroplast DNA.";
RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in protein precursor import into chloroplasts. May
CC be part of an intermediate translocation complex acting as a protein-
CC conducting channel at the inner envelope.
CC {ECO:0000250|UniProtKB:P56785}.
CC -!- SUBUNIT: Part of the Tic complex. {ECO:0000250|UniProtKB:P56785}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast inner membrane
CC {ECO:0000250|UniProtKB:P56785}; Multi-pass membrane protein
CC {ECO:0000255}.
CC -!- MISCELLANEOUS: There is a partial copy of the N-terminus (positions 1-
CC 343) of ycf1 in the inverted repeat (BAF50335).
CC -!- SIMILARITY: Belongs to the TIC214 family. {ECO:0000305}.
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DR EMBL; AP009372; BAF50347.1; -; Genomic_DNA.
DR EMBL; AP009372; BAF50335.1; -; Genomic_DNA.
DR RefSeq; YP_001123510.1; NC_009271.1.
DR RefSeq; YP_001123522.1; NC_009271.1.
DR AlphaFoldDB; A4QKZ2; -.
DR PRIDE; A4QKZ2; -.
DR GeneID; 4962711; -.
DR GeneID; 4962753; -.
DR GO; GO:0009706; C:chloroplast inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR InterPro; IPR008896; TIC214.
DR PANTHER; PTHR33163; PTHR33163; 1.
DR Pfam; PF05758; Ycf1; 1.
PE 3: Inferred from homology;
KW Chloroplast; Membrane; Plastid; Plastid inner membrane; Protein transport;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..1795
FT /note="Protein TIC 214"
FT /id="PRO_0000326568"
FT TRANSMEM 19..39
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 68..88
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 91..111
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 133..153
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 176..196
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 227..247
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 1490..1517
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1490..1507
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1795 AA; 214567 MW; 56EF66277E348528 CRC64;
MMVFQSFILG NLVSLCMKII NSVVVVGLYY GFLTTFSIGP SYLFLLRARV MDEGEEGTEK
KVSATTGFIA GQLMMFISIY YAPLHLALGR PHTITVLALP YLLFHFFWNN HKHFFDYGST
TRNEMRNLRI QCVFLNNLIF QLFNHFILPS SMLARLVNIY MFRCNNKMLF VTSSFVGWLI
GHILFMKWVG LVLVWIQQNN SIRSNVLIRS NKYKFLVSEL RNSMARIFSI LLFITCVYYL
GRIPSPIFTK KLKGTSETGG TKQDQEVSTE EAPFPSLFSE EGEDLDKIDE MEEIRVNGKD
KINKDDEFHV RTYYNYKTVS ENVDGNKENS NLEFFKIKKK EDHFLWFEKP FVTLVFDYKR
WNRPNRYIKN DKIENTVRNE MSQYFFYTCQ SDGKERISFT YPPTLSTFFE MIKKKIPSFT
REKTPSDPIS TYWSLINEEK KENLKKEFLN RIEALDKEWS VENILEKTTR FCHNEAKKEY
LPKIYDPFLH GISRGRIKKL PPFQIITQTY RKNNIGASWI NKIHGLLLKI NYHKFEQTIE
KFNSKSLSIE KKLSFFSEPQ QEEKIDSEEE IKIFKFLFDV VRTHSNDQTR IKNFIDFYEI
NKKVPRWSYK LISELEELEG ENEENVPMEP GIRSRKAKRV VIFTDKEPHN EIYTNLKDNQ
NSDQKDEMAL IRYSQQSDFR REIIKGSMRS QRRKSIIWEF FQAKVHSPLF FDRKDKLFFF
SFDIWGLKKK ILRNFMWKNK KKKIDKKEEE QSKIEEKRRI EIAETWDSFL FAQIIRGSLL
VTQSILRKYI ILPLLIIIKN SVRMLLFQFP EWSEDLKDWK REMHIKCTYN GVQLSETEFP
KNWLTDGIQI KILFPFYLKP WHKSKFQASQ KVRLKKTKDK GEKNDFCFLT VWGMETELPF
GSAQKKPSFV EPISKELKKR IKKFKTKPFL VLRIFKKRAT ILLKVTKEMK NWTLKNFLFI
KGKIKDLSKQ NLIPLFGPSE IYELNETKKD SIISNQIIHQ LSVQNKSMEW TNSSLSEKKK
KNLIDRIKTI RNKIDEISKE KQNLTNSCTK LRYDSKIIES SKKIWQTFKR KNTRLIRKSI
FFIKFCIEQL SIAIFLGIIN IQRITTQLFF ESTKIILDKY IYKNDEIGEK KNKKNTIYFI
STIKNLISNK KKISYDLCSL SQAYVFYKLS QIKISNFSKL KAVLEYNICI TSFFVKNQIK
VFFQEQGIFQ YELKNKTFLN SEVNQWKNWL RSHYQYNLPQ IAWARLVTEK WKKKITQDSL
VLNPSLTKED SYEKKIVDNY KKQNFFEANS LVTPKHNLKK DSIYNIFCYK SIHCTEKNVD
MSISIALDNC LVSSFLEKYN IRGIGEIQYR KYLDWRILNF WFTKKVNIEP WVDTKSKQKY
INTKVQNYQR IDKITKTGLA NQKRNFFDWM GMNEEILNHR ITNFEFVFFP EFVLFSSTYK
MKPWVIPIKL LLLNFNENIN VNKKITRKKK GFIQSNEKKS RRFYNLNKDE KESTGQVEFE
SDKEQQRNSE SALSNQEKNI EENYAESTIK KRKNKKQYKS NTEAELDLFL TRYSRFQLRW
NCFFNQKILD NVKVYCLLVR LKNPNEIAIS SIERGEMSLD ILMIEKNFTF AKLMKKGILI
IEPVRLSVQN DGQLIIYRTI GISLVHKNKN KDKISKRYKK KSYIDKKKID KSITKYQNKT
VNRKKNNYDF FVPENILSPK RRREFRILIC FNFKKKTARD RNSRFDKNIQ NLPTVLHKKK
DLDKDKKNLI NLKSFLWPNF RLEDLACMNR YWFNTTNGNH FSMIRIHMYT RFPIH
