TI214_DAUCA
ID TI214_DAUCA Reviewed; 1826 AA.
AC Q0G9Q4;
DT 28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT 03-OCT-2006, sequence version 1.
DT 25-MAY-2022, entry version 36.
DE RecName: Full=Protein TIC 214 {ECO:0000250|UniProtKB:P56785};
DE AltName: Full=Translocon at the inner envelope membrane of chloroplasts 214 {ECO:0000250|UniProtKB:P56785};
DE Short=AtTIC214 {ECO:0000250|UniProtKB:P56785};
GN Name=TIC214 {ECO:0000250|UniProtKB:P56785}; Synonyms=ycf1;
OS Daucus carota (Wild carrot).
OG Plastid; Chloroplast.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; campanulids; Apiales; Apiaceae; Apioideae; Scandiceae; Daucinae;
OC Daucus; Daucus sect. Daucus.
OX NCBI_TaxID=4039;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Danvers Half-long;
RX PubMed=16945140; DOI=10.1186/1471-2164-7-222;
RA Ruhlman T., Lee S.-B., Jansen R.K., Hostetler J.B., Tallon L.J., Town C.D.,
RA Daniell H.;
RT "Complete plastid genome sequence of Daucus carota: implications for
RT biotechnology and phylogeny of angiosperms.";
RL BMC Genomics 7:222-222(2006).
CC -!- FUNCTION: Involved in protein precursor import into chloroplasts. May
CC be part of an intermediate translocation complex acting as a protein-
CC conducting channel at the inner envelope.
CC {ECO:0000250|UniProtKB:P56785}.
CC -!- SUBUNIT: Part of the Tic complex. {ECO:0000250|UniProtKB:P56785}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast inner membrane
CC {ECO:0000250|UniProtKB:P56785}; Multi-pass membrane protein
CC {ECO:0000255}.
CC -!- SIMILARITY: Belongs to the TIC214 family. {ECO:0000305}.
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DR EMBL; DQ898156; ABI32482.1; -; Genomic_DNA.
DR RefSeq; YP_740175.1; NC_008325.1.
DR AlphaFoldDB; Q0G9Q4; -.
DR PRIDE; Q0G9Q4; -.
DR GeneID; 4266818; -.
DR OrthoDB; 53153at2759; -.
DR GO; GO:0009706; C:chloroplast inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR InterPro; IPR008896; TIC214.
DR PANTHER; PTHR33163; PTHR33163; 1.
DR Pfam; PF05758; Ycf1; 1.
PE 3: Inferred from homology;
KW Chloroplast; Membrane; Plastid; Plastid inner membrane; Protein transport;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..1826
FT /note="Protein TIC 214"
FT /id="PRO_0000262606"
FT TRANSMEM 18..38
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 67..87
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 127..147
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 175..195
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 221..241
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 774..794
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1081..1101
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 250..308
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1032..1057
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 265..308
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1826 AA; 218423 MW; 0B708C6A7F3223F9 CRC64;
MILKSFLLGN LVSLCMKIIN SVVVVGLYYG FLTTFSIGPS YLFLLRAQVM EEGEEGTEKK
VSATTGFITG QLMMFISIYY APLHLALGRP HTITVLALPY LLFHFFWKNH KNFFDYGSTT
RNSMRNLSIQ CVFLNNLIFQ LFNHFILPSS MLARLVNIYM FRCNNKMLFV TSSFVGWLIG
HILFMKWVGL VLVWIRQNNS IRSNKYIRSN KSELINYMAR IFSILLFITC VYYLGRIPSP
IFTKKLNPQT EEGWESEEET DVEIETASET KGTKQEQEGS TEEDPSPSLF SEEKEDPDKI
DETEEIRVNG KEKTKDEFHF TEIRYNNSPV YKGLFWFEKP LLTFLFDYKR WNRPLRYIKN
NRFERTTRKE MSQYFFYTCR SDGKERISFT YPPSLSTFGE MIQRRMSLPT LEKLSSAELY
NHWVYTNQHK NNNLNNEFLN RIEALDTGFF SLDILEKSTR LCNDKTRKYY LPKMYDPILN
GLYRGTIQKK ISPSIINKIS LENFIETLEI NKIHSLLLPD TDYQEFEQKI DQFDKKTFST
ENRHLFTLIS KLDRESGSRK GLSLFSEKEQ GGVGSKKRDK FYKFLLNTIL TSPNDQKTKQ
KFVIKEISKK VPRWSYKLIT ELEFLSGTAH EGLPLDYQIR SRKRDGIIIY RPTKRSRNAS
IKNWMSFRDY SEESDFRREF IKGSMRVQRR KTVIWKLFQA NAHSPLFLDR IKKYPLFSFN
IPERMKSFFR NCMGKGSGLK DYTEEQEDKI KEKASIKIAE AWDFIPYPQA TRSLILIIQS
IFRKYILLPS LIIVKNIGRI LLSQPPEWTE DFDEWNREKH IICTYNGVQV SEFELPKNWF
KDGIQIKIVF PFYLKPWHRS KLRTSFSSYK DLKKEEQPKF YFLTAWGAQT TLNFGSIPPK
PSFFKPILKE LKKKMQKTKN NNLKVLRVLK ERTKDFLQDS KEPKEVIIKN VLFLFIKRIK
KELFKIHPTR LFILKKVYES GETNKKKDYI IRNQQIHDSF IKIKSTDNKN DSLRDKKIKN
LTDRTSTIRT KTKGLMKEKN SNAKKRGSPN KTSFNRKKKS PNILLKILKI KRRSTRLIYK
FYLFITIFIK RIYIDIFVCI IHIARISTQL LLESINFCFD KYIYIYNNKT NKTNYNNKTN
QEIKKKKEIN FISTIKSALY NIQNSKRNSR LFFDLSSLSQ AYVFYKLSQT PIIHFYKLRD
IFEYNGTPFF LKTAMKNYFL TQGIFHSELR HTKLSSYETN QWKSWLRGHY QYNLSQIRWS
GLIPKKWRTT INEGGMTPNK DLTKCNSYEK DRLLYHKKQK DFKVYPLPNQ KDNFLKYYIY
DLFSYKSINS EIKKSSYIFF GSPSELKNNQ KIAFNYNKKK QNLSENLEEI PINHYLETGD
IMYMKKNPDR KYFDWTILNF FIRQKIDIEA WTKMDYNSNI NTKLGNTNYH KIYKMDKNAI
LSLTIHQDLE RNPINDKKIF FDWMEMNEEI LNPISTNLKL TFFPEFVPLY NVYKTKPWII
PSKLLLLNLN KKKNINENKK FHFFRPSNEK IYYELMNRNQ EEKKTAGRRG LRSYAQNQDK
MKKKYKIRNK MRREIIFLRK HYLLFQWIID DGLIPKLTER MINNIKIYCY LLGLRNPRDT
TISSIQRKEL NLDIMVIRQK LTPIELNKKG IFFLDPTRLS VKNDGYFIIY QTVGISLVHK
SKYQTPQRYR EQRYINKKKL DESIPRYQII LRKRDKKHYD FVVPENILSS RRRRELRILL
SFNSKNLNSV DKNPVFCNKK NIKRRNPFLD QKKHLDRDKN ELIKLKLFLW PNYRLEDLAC
MNRYWFNTNN GSRFSILRIY PQFKIG
