TI214_DIOEL
ID TI214_DIOEL Reviewed; 1858 AA.
AC A6MMQ5;
DT 08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 24-JUL-2007, sequence version 1.
DT 25-MAY-2022, entry version 35.
DE RecName: Full=Protein TIC 214 {ECO:0000250|UniProtKB:P56785};
DE AltName: Full=Translocon at the inner envelope membrane of chloroplasts 214 {ECO:0000250|UniProtKB:P56785};
DE Short=AtTIC214 {ECO:0000250|UniProtKB:P56785};
GN Name=TIC214 {ECO:0000250|UniProtKB:P56785}; Synonyms=ycf1;
OS Dioscorea elephantipes (Elephant's foot yam) (Testudinaria elephantipes).
OG Plastid; Chloroplast.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Dioscoreales; Dioscoreaceae;
OC Dioscorea.
OX NCBI_TaxID=145284;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=17644003; DOI=10.1016/j.ympev.2007.06.004;
RA Hansen D.R., Dastidar S.G., Cai Z., Penaflor C., Kuehl J.V., Boore J.L.,
RA Jansen R.K.;
RT "Phylogenetic and evolutionary implications of complete chloroplast genome
RT sequences of four early-diverging angiosperms: Buxus (Buxaceae),
RT Chloranthus (Chloranthaceae), Dioscorea (Dioscoreaceae), and Illicium
RT (Schisandraceae).";
RL Mol. Phylogenet. Evol. 45:547-563(2007).
CC -!- FUNCTION: Involved in protein precursor import into chloroplasts. May
CC be part of an intermediate translocation complex acting as a protein-
CC conducting channel at the inner envelope.
CC {ECO:0000250|UniProtKB:P56785}.
CC -!- SUBUNIT: Part of the Tic complex. {ECO:0000250|UniProtKB:P56785}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast inner membrane
CC {ECO:0000250|UniProtKB:P56785}; Multi-pass membrane protein
CC {ECO:0000255}.
CC -!- SIMILARITY: Belongs to the TIC214 family. {ECO:0000305}.
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DR EMBL; EF380353; ABR01477.1; -; Genomic_DNA.
DR RefSeq; YP_001294400.1; NC_009601.1.
DR AlphaFoldDB; A6MMQ5; -.
DR PRIDE; A6MMQ5; -.
DR GeneID; 5236670; -.
DR GO; GO:0009706; C:chloroplast inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR InterPro; IPR008896; TIC214.
DR PANTHER; PTHR33163; PTHR33163; 1.
DR Pfam; PF05758; Ycf1; 1.
PE 3: Inferred from homology;
KW Chloroplast; Membrane; Plastid; Plastid inner membrane; Protein transport;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..1858
FT /note="Protein TIC 214"
FT /id="PRO_0000326573"
FT TRANSMEM 18..38
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 64..84
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 85..104
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 128..148
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 176..196
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 219..239
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 246..287
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1561..1604
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 262..279
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1571..1595
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1858 AA; 222975 MW; 4DE1E2459EB4B4B9 CRC64;
MIFKSFLLGN LLSLCIKIIN SVVVVGLYYG FLTTFSIGPS YLFLLRARVM EEGTEKEVSA
TTGFITGQLM MFISIYYAPL HLALGRPHTM TVLVLPYLLF HFFWKNQKNF TSIRNASTRD
SMCNLRNLNI QCVFLNNLIF QLLNHFILPS STLARLVNIY MFRCNNKMLF VTSSFVGWLI
GHFLFMKWLG LVLFWIPQNY SIRSNKYLVS ELRNSMGRIF SILLFITCVY YLGRMPSPIV
TKKLKEISET EEGGESEEES NVETTFETRD PKQEQEESTE EDPYLCWEEK EDPEKIDERK
EIQVNEKEKT KNEFDFHFKE TYYKDNPVHE DSYLDTYQDN WQLGRLKEDK KQKTYLIYKK
PLVNFLFDYK RWNRPLRYIK NDRFENVVRN EISQYFFYTC PSDGKKRISF TYPLSLSTLS
EMIERKIFLY TTEKLSHEGL YNYWVYTNEQ KKYNMSNELL SRIKVLEKEK KSLVIDMLEK
RTRLYNDENE QKCLHKTYDP LLNGPYRGTI KKLYSKNDLI SNRNRTTEDA IETFWINKIH
DILYIYNDSR KFEHQKNLLD GESVLNFIGN SLSSISIGKF YLESTHSFNL KKFSLLSLLA
EQKTIDLESQ AKSLKFRIDG ITTDLNDETT IRNKSIGIEE ILKKVPRWSY KLTNGLEEED
ENEEESTEDP GLRSRKAKRV VIYTDNDQNT NSITTNNSIS NNDEVEEVAL IRYSQQSDFR
RDIIKGSMRA QRRKTVTWEM FQANMHSALF LDRIDKTFFF SSFDISEMRN IIFRNWLRRE
PELRISECEE ETKEKGKKYK EKKEENKRIR IAISETWDTI IFAQAIRGSM LITQSFLRKY
IILPSLIIAK NIGRILLFQF PEWDEDLKEW NREMHVKCTY NGVQLSETEF PKDWLTDGIQ
IKILFPFCLK PWRKPKVRSN LTKKKRKKEN FCFLTIWGME AELPFGSPRK QSSFFEPIYK
ELEKKMRKVK KKFFRVLRVF KERKKGFLKV RKEKTGWILP IVLIRKQIMK EFEKINPIFL
FKLSKVKVYE PHEKKKNDKT PNKITRESSI QIRSMNWTNY SLIEKKMKDL ADRTLTTRNQ
IEQITKDNKK IAIICDGKRL ESRKKIFQIL KRQYIRLLRK SDSFMKSFIE KIYINIFLCT
INIFSINIQL FFESKKKNLN KSTIYNDETN QNTMNFISTL KKSFSNTINS TTLITNISNN
SNIYYNLSSL SQAYVFYILS QTQLFNKYHL RSVLHYDRTY PFLRDTIKNY CMTQGIFDTK
SRYKKIHKSE INEWKNWLRD HYQYKLSQTK WFRLVPQKWG NKVNKHYIIQ NKDKDSIKLD
SYKKEKDQLI HYMKQNHNYD AVDSLTSQKE KLKKHYRYDL LSHEYMNYGN REDSYIYEST
LQVNGNQEIS YNLYTMKAES YYILITIVIN DYLEEGYIVD MDQNMNRKYF DSRILCFPIR
KNIDIEAWIN AHIDTKINKN LKTETNNYQK LAKKKLFVFD WIGMNEERLY HKISNPEPWF
FPEFWLLFNA YKIKPQIIPI QLLFLNFYFY ENISQSNNIN LDQKKNPHIS SNQKEYLEFE
NSNQEKNEQQ GQGDLRSDLR KQKKKDVEEN HTKSEIKKHK KKKQSKSNKE AELYFFLKKY
LLFQLRWDDS LNQRMIDNIK VYCLLLRLIN TKEIVISSIQ RGEMCLDVML IQKDLALTEL
IKKGILIIEP IRLFLERGVK LIIYQTIGIS LINKNQTNGK YLKKRYVDKK SFDRYIGRYN
NMLANGDKNH YDFFVPENIL SPRRRRELRI LICFNSCNWN VVDRNPAFCN ENKIKNYRQF
LNKHLNTDTN KFTKFKLFLW PNYRLEDLAC MNRYWFDTNN GSRFSMSRIH MYPRFRII
