ID   TI214_DRANE             Reviewed;        1780 AA.
AC   A4QL79; A4QL67;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   15-MAY-2007, sequence version 1.
DT   25-MAY-2022, entry version 34.
DE   RecName: Full=Protein TIC 214 {ECO:0000250|UniProtKB:P56785};
DE   AltName: Full=Translocon at the inner envelope membrane of chloroplasts 214 {ECO:0000250|UniProtKB:P56785};
DE            Short=AtTIC214 {ECO:0000250|UniProtKB:P56785};
GN   Name=TIC214 {ECO:0000250|UniProtKB:P56785}; Synonyms=ycf1-A;
GN   and
GN   Name=TIC214 {ECO:0000250|UniProtKB:P56785}; Synonyms=ycf1-B;
OS   Draba nemorosa (Woodland whitlowgrass).
OG   Plastid; Chloroplast.
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Arabideae; Draba.
OX   NCBI_TaxID=171822;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Hosouchi T., Tsuruoka H., Kotani H.;
RT   "Sequencing analysis of Draba nemoroza chloroplast DNA.";
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in protein precursor import into chloroplasts. May
CC       be part of an intermediate translocation complex acting as a protein-
CC       conducting channel at the inner envelope.
CC       {ECO:0000250|UniProtKB:P56785}.
CC   -!- SUBUNIT: Part of the Tic complex. {ECO:0000250|UniProtKB:P56785}.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast inner membrane
CC       {ECO:0000250|UniProtKB:P56785}; Multi-pass membrane protein
CC       {ECO:0000255}.
CC   -!- MISCELLANEOUS: There is a partial copy of the N-terminus (positions 1-
CC       344) of ycf1 in the inverted repeat (BAF50422).
CC   -!- SIMILARITY: Belongs to the TIC214 family. {ECO:0000305}.
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DR   EMBL; AP009373; BAF50434.1; -; Genomic_DNA.
DR   EMBL; AP009373; BAF50422.1; -; Genomic_DNA.
DR   RefSeq; YP_001123597.1; NC_009272.1.
DR   RefSeq; YP_001123609.1; NC_009272.1.
DR   AlphaFoldDB; A4QL79; -.
DR   PRIDE; A4QL79; -.
DR   GeneID; 4964772; -.
DR   GeneID; 4964780; -.
DR   GO; GO:0009706; C:chloroplast inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR008896; TIC214.
DR   PANTHER; PTHR33163; PTHR33163; 1.
DR   Pfam; PF05758; Ycf1; 1.
PE   3: Inferred from homology;
KW   Chloroplast; Membrane; Plastid; Plastid inner membrane; Protein transport;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..1780
FT                   /note="Protein TIC 214"
FT                   /id="PRO_0000326574"
FT   TRANSMEM        19..39
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        68..88
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        91..111
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        133..153
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        176..196
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        227..247
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          251..275
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        253..268
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1780 AA;  212801 MW;  9096EB0EE1761C6B CRC64;
     MMVFQSFILG NLVSLCMKII NSVVVVGLYY GFLTTFSIGP SYLFLLRARV MDEGEEGTEK
     KVSATTGFIA GQLMMFISIY YAPLHLALGR PHTITVLALP YLLFHFFWNN NKHFFDYGST
     TRNEMRNLRI QCVFLNNLIF QLFNHFILPS SMLARLVNIY MFRCNNKMLF VTSSFVGWLI
     GHILFMKWVG LVLVWIQQNN SIRSNVLIRS NKYKFLVSEL RNSMARIFSI LLFITCVYYL
     GRTPSPIFTK KLKGTSETEE RGGTKQDQEV STEEAPFPSL FSEEREDLDK IDEMEEIRVN
     GKDKINKDDE FHVRTYYKKV SENRDGNKEN SNLKFFKIKK KEDHFLWFEK PFVTLVFDYK
     RWNRPNRYIK NEKIENTIRN EMSQYFFYTC KSDGKERISF TYPPNLSTFF EMIQKKIPSF
     TREKAPADQM SAYWSLMNEE KKNNLKNVFF NRIEALDKKR SFENILEKTT RFCHNETKKE
     YLPKLYDPFL HGISRGKVKK LLPFQIITET YINIGLGGSW INKIHGILLK INSKKFEQTL
     EKFNRKSLSV EKKLSFFSEP REEKSHSDEE IQIFKILFDV VITDNNNQTL IKNVIYFHEI
     NKSVPQWSYK LTSELEELEG ENEENVPTEP GIRSRKAKPV VVFTDKESHN GIYTNLKDNQ
     NFDQKDEMAL IRYSQHSDFR RDLIKGSMRS QRRKTVIWEF FQAKVHSPLF FDRIDKLFFF
     SFDLWGLKKT ILRNLMWKKK KKKIDKNEEE QLKRKERRRM EIAETWDSFL FSQTIRGFLL
     VTQSILRKYL ILPLLIIIKN STRALLFQVP EWSEDLKDWK REMHIKCTYN GVQLSETEFP
     RNWLTDGIQI KIIFPFYLKP WHKSKVQSSQ KARLKKTKDK GEKNDFGFLT VWGMETELPF
     GSAKKKPSFF EPIFKELKKR IKKFKRKPFW VLSIFKERAT ILLKVAKEIK NWILQNLLFL
     KGKIKNISKQ NRMPLFDLRE ISELNETKKD SIMSNQMIYG LSVQKKSMEW TNSSLSENKI
     KNLIDRIKTI KNQTEEILKE KENLTNTNRC NKPRYDSKII ESSKKSWQTF KRKNIRLIRK
     FFFFFKFCIE QLFRTIFLGI INIPRITTQL FFESTKEILD KSIYIYKNEE NGEKNKNKKN
     TIFFISTIKN LISKKKIFSY DLCSLSQAYV FYKLSQIQVS NFSKLKAVLE YNICITSFFI
     KNQLKDLVQE QGILDYELKD KTFLNSQVNQ WKHWLRSNSQ YNLPQVAWAR LVTQRWKKKI
     NQDSLVLNQS LIKTDSYEKN KFDKFDNYKK QNFFEANSLL NPKLNLKKDY RYNLFCYKFI
     HSREKMFDMS IGIALDNCLV SSFLEKYNIR VIEEIGHRKY LDWRILNFLF IKKVNMRPWV
     DTKSKKKDSR TKVQNYQKID KITKTDLANK KSFFFDWMGM NEEILNRRLT NFEFFFFPEF
     VLFSSTYKTK PWVIPIKLLL FNFNEKKNVN KKITLKNKGF ISSNEKGSLW FYNLNKEENG
     LAGQGELESD NEKQRNPESV LLNQEKNIDE NYAESKIKKR QNKKQYKSNT EAELELFLTR
     YSRFQLRWNC FLNQKIINNI KVYCLLVRLK NPNEITISCI ERGELSLDIL MIEKNFTFTK
     LMKKGMLIVE PVRLSVKNDG QLIIYRTIGI SLVHKNKPKI SKRYKNIDKK NNYDCFIPEN
     ILSPKRRREF RILICFNLKK KNARDRNSRF DKNIKNLTTV LHKKKDLDKD KKTLIKLKSF
     LWPNFRLEDL ACMNRYWFNT TNGNRFSMIR IHMYTRFKIH