TI214_DRIGR
ID TI214_DRIGR Reviewed; 1857 AA.
AC Q06GT8;
DT 28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT 31-OCT-2006, sequence version 1.
DT 25-MAY-2022, entry version 36.
DE RecName: Full=Protein TIC 214 {ECO:0000250|UniProtKB:P56785};
DE AltName: Full=Translocon at the inner envelope membrane of chloroplasts 214 {ECO:0000250|UniProtKB:P56785};
DE Short=AtTIC214 {ECO:0000250|UniProtKB:P56785};
GN Name=TIC214 {ECO:0000250|UniProtKB:P56785}; Synonyms=ycf1;
OS Drimys granadensis.
OG Plastid; Chloroplast.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Magnoliidae; Canellales; Winteraceae; Drimys.
OX NCBI_TaxID=224735;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=17020608; DOI=10.1186/1471-2148-6-77;
RA Cai Z., Penaflor C., Kuehl J.V., Leebens-Mack J., Carlson J.E.,
RA dePamphilis C.W., Boore J.L., Jansen R.K.;
RT "Complete plastid genome sequences of Drimys, Liriodendron, and Piper:
RT implications for the phylogenetic relationships of magnoliids.";
RL BMC Evol. Biol. 6:77-77(2006).
CC -!- FUNCTION: Involved in protein precursor import into chloroplasts. May
CC be part of an intermediate translocation complex acting as a protein-
CC conducting channel at the inner envelope.
CC {ECO:0000250|UniProtKB:P56785}.
CC -!- SUBUNIT: Part of the Tic complex. {ECO:0000250|UniProtKB:P56785}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast inner membrane
CC {ECO:0000250|UniProtKB:P56785}; Multi-pass membrane protein
CC {ECO:0000255}.
CC -!- SIMILARITY: Belongs to the TIC214 family. {ECO:0000305}.
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DR EMBL; DQ887676; ABH88356.1; -; Genomic_DNA.
DR RefSeq; YP_784445.1; NC_008456.1.
DR AlphaFoldDB; Q06GT8; -.
DR PRIDE; Q06GT8; -.
DR GeneID; 4363566; -.
DR GO; GO:0009706; C:chloroplast inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR InterPro; IPR008896; TIC214.
DR PANTHER; PTHR33163; PTHR33163; 1.
DR Pfam; PF05758; Ycf1; 2.
PE 3: Inferred from homology;
KW Chloroplast; Membrane; Plastid; Plastid inner membrane; Protein transport;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..1857
FT /note="Protein TIC 214"
FT /id="PRO_0000262607"
FT TRANSMEM 18..38
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 64..84
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 87..107
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 124..144
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 172..192
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 221..241
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 246..304
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 612..631
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 740..764
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1547..1579
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 267..283
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1857 AA; 220673 MW; BBB4ECE4FB2BCFA5 CRC64;
MILKSFLLGN LLSLCMKIIN SVVVVGLYYG FLTTFSIGPS YLFLLRARVM EEGTEKEVSA
TTGFITGQLM MFISIYYAPL HIALGRPHTI TVLVLPYLLF HFFWNNHKHF FDYGSTTRNS
MRNLSIQCVF LNNLIFQLFN HFILPSSTLA RLVNIYMFRC NNKMLFVTSS FIGWLIGHIL
FMKWVGLVLF WIRQKNSIRS NVLIRSNKYL VSELRNSMAR IFSILLFIIC VYYLGRIPSP
IVTKKLKETS ETEERGESEE ETDVEIETTS ETKGTKQEQE GSTEEDPSFC SEEKEDPDKL
DETEEIRVNG KEKLKDKEEF HFWFEKALST QLFEKKRWNR PLRYIKNDRL ENSVRTEMSQ
YFFSTTCTCG KKIISFTFPP SLSTFWKMIQ RNISLCTTEK LSPKDLYNHW VYTNEQKRHN
LSNEFRNRME ALDKGSLALD VLEKRIRFCN DENEQECLPK VYDPFLNGPY RGTIKKGYSR
PIMDDSIIST EDSTGMVWIN RIHGILPNLS DYQEFEDKMD AFNEELVSPD IDHSLNSISE
LAEESRPSLN LKGLTLLAEQ RRLDSENQMK RLKFLFYAVK TDPNDQTIRN KSIGIEEIGK
KVPRWSYKLT DDLEEQEAEN EEGSTEDPGI RSRKAKRVVI YTYNDQNINT HTSTNTNSDS
DQAEEVALIR YSQQSDFRRN LIKGSMRAQR RKTVTWEMFQ ANVHSPLFLD RIDKTFFFSF
DISGMMNPFL RNWMGKDPQF KTSDSEEEEA KEKNKKKKEQ KEENERIAIS ETWDTIIFAQ
AIRGSMLVTQ SIFRKYIILP SLIIAKNLGR MLLFQFPEWY EDLKEWNKEM HVKCTYNGVQ
LSETEFPKNW LTDGIQIKIL FPFCLKPWRG SKLQFHHRDP MKNKVKKENF CFLTVWGMET
ELPFGSPRKE PSFFEPIFKE LEKKMRKVQK KYFRVLKFLK ERTKWCLKVS KEKIRWVIKI
VLFIKRIMKE LAKVNSILLF GLRKGYQPSE TGKDSIISNK ITHESTIQIR PMGWTNYSLT
EKKMKDLADS TTTIKNQIER IKKDKKKIFL TTDINIIPNK TSFDDERSES QKHIWQRSKK
RSARLIRKSQ YFIKYFIEII YMDIFLCTIN IPRINAQLFL ESTKNLIDKY IYNNETNTNK
EGIDETNQNK IQFISTIQKS LSILNIRNNN SHIYCDLSFL SQAYVFYKLS QNQEVINKYH
LISVLQYHGA SPFIKHRIKD CTRGIFDSKS RHKKLPNSRM NEWKNWLKRH YQYNLSQNRW
SRLVSKKWRT RVNQRRTIQN KDSKNLDSYE KEKDQFIHYE KENDCAVNSL PSQKEKFKKH
YRYDLLSYKY INYEDRKSSY IYVSPLQING GREIPYNDNT PKPESCYVLG DIAISDYLGE
ESIMDTGKNP DIKYFKWRIL HFFLRKNIDI DTWTDMDTGT NINKNTKNGI NDYEKIDKKD
LFYFTIHQEI KPPNKKKNFF DWMGMNEEMR YRPISNLESW FFPEFVRLYD TYKMKPWIIP
IKLLLLNFHG NENISENKNI SENENINGNQ KKDLRISSNQ KEYLELENRN KEKEQPGQGD
IRSDARNQEN LESDAQNKKK YVEKDYAESD IKKRRKKRKY KSNKEAELEF FLKRYLLFQL
RWDDSLNQRM INNIKVYCLL LRLINPREIA ISSIQRGEMR LDVMLIHKDL TLTELIKRGI
FIIEPARLSI KRDGQFIMYQ TIGISLIHKS KHQTNRECRE KKYVDENSFD GSIAQHGKML
VNGDENHYDL LISENILSPR RRRNLRILMC FNSSNENIVD INPIFFNENN VRNSGQFLDE
DKCLDTDTNK CIQFKLFLWP NYRLEDLACM NRYWFDTNNG SRFSMSRIYM YPQFRIS
