ID   TI214_EUCGG             Reviewed;        1877 AA.
AC   Q49KU0;
DT   28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2005, sequence version 1.
DT   02-JUN-2021, entry version 37.
DE   RecName: Full=Protein TIC 214 {ECO:0000250|UniProtKB:P56785};
DE   AltName: Full=Translocon at the inner envelope membrane of chloroplasts 214 {ECO:0000250|UniProtKB:P56785};
DE            Short=AtTIC214 {ECO:0000250|UniProtKB:P56785};
GN   Name=TIC214 {ECO:0000250|UniProtKB:P56785}; Synonyms=ycf1;
OS   Eucalyptus globulus subsp. globulus (Tasmanian blue gum).
OG   Plastid; Chloroplast.
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Myrtales; Myrtaceae; Myrtoideae; Eucalypteae; Eucalyptus.
OX   NCBI_TaxID=71271;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16303753; DOI=10.1093/dnares/dsi006;
RA   Steane D.A.;
RT   "Complete nucleotide sequence of the chloroplast genome from the Tasmanian
RT   blue gum, Eucalyptus globulus (Myrtaceae).";
RL   DNA Res. 12:215-220(2005).
CC   -!- FUNCTION: Involved in protein precursor import into chloroplasts. May
CC       be part of an intermediate translocation complex acting as a protein-
CC       conducting channel at the inner envelope.
CC       {ECO:0000250|UniProtKB:P56785}.
CC   -!- SUBUNIT: Part of the Tic complex. {ECO:0000250|UniProtKB:P56785}.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast inner membrane
CC       {ECO:0000250|UniProtKB:P56785}; Multi-pass membrane protein
CC       {ECO:0000255}.
CC   -!- SIMILARITY: Belongs to the TIC214 family. {ECO:0000305}.
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DR   EMBL; AY780259; AAX21086.1; -; Genomic_DNA.
DR   RefSeq; YP_636357.1; NC_008115.1.
DR   GeneID; 4108438; -.
DR   GO; GO:0009706; C:chloroplast inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR008896; TIC214.
DR   PANTHER; PTHR33163; PTHR33163; 1.
DR   Pfam; PF05758; Ycf1; 1.
PE   3: Inferred from homology;
KW   Chloroplast; Membrane; Plastid; Plastid inner membrane; Protein transport;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..1877
FT                   /note="Protein TIC 214"
FT                   /id="PRO_0000262608"
FT   TRANSMEM        18..38
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        67..87
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        90..110
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        127..147
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        175..195
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        224..244
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          251..308
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        270..286
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1877 AA;  224561 MW;  3B33DAAF03EA63E2 CRC64;
     MILKSFLLGN PVSLCMNIIN SVVMVGLYYG FLTTFSIGPS YLFLLRARVL EEGEEGTEKK
     VSATTGFIAG QLMMFISIYY APLHLALGRP HTITVLALPY LLFHFFWNNH KHFFDYGSTT
     RNSMRNLSIQ CVFLNNLIFQ LFNHFILPSS MLARLVNIYM FRCNNKMLFV TSSFVGWLIG
     HIFFMKWVEL VLVWIQQNNS IRSNKYIRSN KYLVSELRNS MARIFSILLF ITCVYYLGRI
     PSPIVTKKFK ETSETEERGE GEEETDVEIE TTFETKGTRQ EQEGSTEEDP SLFSEEKEDP
     DKIDEREEIR VNEKEKTRDE FNFQETFYKD SQVYKTSYMD RNKNKENSKL EIFKLKEDPF
     FLWFEKPLVT LLFDYKRWNR PLRYIKNNHF ENAVRNEVSQ YFFYICRNNG KERISFTYPP
     SLSTFLKMIE RKISLLTKEK LPSDELYDHW IYTNDQKKNN LSKKFRNQME TVNKESITLD
     VFEKRTRLCN DENKKKYLPK IYDPFLNGPG RGRVKFFFSS QILNKMSIKN YIETGWINKI
     HSILFTTDQE KLEEKIDTFD KNSLSTEKKL SLFPFPETEQ GRIHSEDQIK ILKIFFNAVI
     TEPKTKRIKK KSIGIKEIST KVPSWSYKLI NDLEQQEGEN EEMVAEDHEI RSRKTKHVLI
     FTDNDENTDA NSKNTNNLDE ADEVTFIRYS QQSDFRRDII KGSMRAQRRK TVICELFQAN
     VHSPLFLDRI GKPLFSFDIS GMIKFILKKW MYKKTTELRI SDYTQEKKKE NEKKKEEDKR
     EEYKRQEKAR IEIAQTWDRV LFAQAIRGSL LVTQSFLRKY ILFPSVIIAK NIARILLFQF
     PEWSEDLKDW NREMHVKCTY NGVQLSETEF PKNWLTDGIQ IKILFPFYIK PWHRSKVPPR
     QKDRLRNKEQ KNDFCFLTVW GMETEVPFGS PRKQRSFFEP IFKELRKKII KLQKNPFLVI
     QVLKERINLF LNLSKERKKS VMKTILFLKG IIKELSKRNP IQLFGLRKID ELSETKKEKN
     GVISNGMINE SSIQIRFMDL TDSSLTEKKM KDLDDRTSTI RNQIEKITKD NKKGFLTPEI
     NINISSNKIS YPTKLLASIK NIWQKLKKFK RINVRLIRKS YSFFKFLIER IYINILICII
     NSPRITTQLF FDNSTKMIDK YIYNNETNKE KIAKTNKNTI RFIWTKKKSI SDISKKNSKI
     LLSSFSQAYV FYQLYQTQFC NLYKLRYVLQ YHGTSFFLKN EIKDYFETQG IFYPELKHKN
     ILNSEMIQWK NWLRGHYQYD LSPIRWYRLV PHKWRNRFNQ TRLVQNKDLN KRHSDEKDRL
     ILINYKKLND FELNSLSNSK YNLQKYYGYD LFSYKSINYE NKKDSHIYVS PLRLNNKQEI
     SYNYNKIYKK GKLINMPGGI IPINLEDDDI LNLXKFTDRK YLDWRIFDFC LRNKVNIESW
     IDIDTNGNKN TKTGFNNYQI IDKMDQKGIF FLKICQNGGI MASNKKKDLF DWMAMNEEIL
     SRPISNLNLW FFPEFVILYN TYIMKPWIIP IQLLLLNFYE NVSENKNITR KNKRDLFLFS
     NEKKSIELEN RNQEEKESAI RDNLESDAQN QANLGSLFSN QEKDIGEDYA SSDMKKRRKK
     KEYKSNTEVE LYFFLKRYLR IQLRWDDSLN QRMINNIKIY CLLLRLINPR EIAISSIQRG
     EMSLDILITQ KDLTLTELMK KGILIIEPIR LSIKNDGQLI MYQSLNISLF HKSKPKINQI
     YREKSYVAKI NLDKSIARHP KMAENRYKND YDLLFVPEKV LSTKRRRELR IRICFNSRKR
     NGIHKNPVFC NNVKNWGEFL DKRKHFEKKK LIKLKFFLWP NYRLEDLSCM NRYWFDTNNG
     GRFTMIRIHM YPRLQIC