ID   TI214_HUPLU             Reviewed;        1658 AA.
AC   Q5SCY7;
DT   28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT   28-NOV-2006, sequence version 2.
DT   25-MAY-2022, entry version 44.
DE   RecName: Full=Protein TIC 214 {ECO:0000250|UniProtKB:P56785};
DE   AltName: Full=Translocon at the inner envelope membrane of chloroplasts 214 {ECO:0000250|UniProtKB:P56785};
DE            Short=AtTIC214 {ECO:0000250|UniProtKB:P56785};
GN   Name=TIC214 {ECO:0000250|UniProtKB:P56785}; Synonyms=ycf1;
OS   Huperzia lucidula (Shining clubmoss) (Lycopodium lucidulum).
OG   Plastid; Chloroplast.
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Lycopodiopsida; Lycopodiales; Lycopodiaceae; Huperzioideae; Huperzia.
OX   NCBI_TaxID=37429;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15788152; DOI=10.1016/j.gene.2005.01.018;
RA   Wolf P.G., Karol K.G., Mandoli D.F., Kuehl J.V., Arumuganathan K.,
RA   Ellis M.W., Mishler B.D., Kelch D.G., Olmstead R.G., Boore J.L.;
RT   "The first complete chloroplast genome sequence of a lycophyte, Huperzia
RT   lucidula (Lycopodiaceae).";
RL   Gene 350:117-128(2005).
CC   -!- FUNCTION: Involved in protein precursor import into chloroplasts. May
CC       be part of an intermediate translocation complex acting as a protein-
CC       conducting channel at the inner envelope.
CC       {ECO:0000250|UniProtKB:P56785}.
CC   -!- SUBUNIT: Part of the Tic complex. {ECO:0000250|UniProtKB:P56785}.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast inner membrane
CC       {ECO:0000250|UniProtKB:P56785}; Multi-pass membrane protein
CC       {ECO:0000255}.
CC   -!- SIMILARITY: Belongs to the TIC214 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAT80755.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AY660566; AAT80755.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; YP_209559.1; NC_006861.1.
DR   AlphaFoldDB; Q5SCY7; -.
DR   GeneID; 3283780; -.
DR   GO; GO:0009706; C:chloroplast inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR008896; TIC214.
DR   PANTHER; PTHR33163; PTHR33163; 3.
DR   Pfam; PF05758; Ycf1; 3.
PE   3: Inferred from homology;
KW   Chloroplast; Membrane; Plastid; Plastid inner membrane; Protein transport;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..1658
FT                   /note="Protein TIC 214"
FT                   /id="PRO_0000262611"
FT   TRANSMEM        28..48
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        52..72
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        82..102
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        130..150
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        165..185
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        199..219
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   1658 AA;  196082 MW;  469D5E981C05F4A2 CRC64;
     MLSVLWVLIS WINISGPIPN ISGSLTLFGL YYGFLAALPI GLSQILTIRA FLLGGNTGGT
     LAVSGSIMGQ LITNLSIYYW PIYVMLLKPH AITLLVLPYM LFYWYRTKDL LYDQPPNPVE
     SLNDAQVRQI FLDSFILSLL NPVILPSPVF ARSLNLFIFR YSNKISFVIS SSFGWLGGYI
     LFINLIKLLM VRIERDSSVN YPLIKSIINQ IFSIIILALR LLYLGRAPVP LFTKKIHDGF
     ESDENQIVKS LWLNKPWPTV LFDYRKWNRP FRYIQNGPNG DSPVKKQVSQ YFFDTCSSDG
     RQRISFTSLP SSSTFQKDLK EYLNISEISP SSEDIYDKWI HIEEKRKNNS NDGLTNRVQA
     LDNRFLMINV TEYRNELCDH KENVSIKTYD PFLNKGFRGK IAISESPWIF DEKPLESTRR
     QIMLNISKRN NKLKDWIYIC WQGLERKKLS LPWEPLTPDA FNSFNLIAKE VSNDEEPRTD
     LKQVDFYEEQ TLVTLDEQNI SSELFATVTE HTNDLHERTT TKSSINWEHV LNLSSKKRDY
     YSRYLENIKW HKLLNYWKKL FLDSSTKVRD TLFLITQAFG IRNEYQVQDV VKEMPRWTSK
     LANYKFDVIG ITFSDVRYRK LKNFDYVFET VDQEIEIETN EPFRIVKRFS QQSDFRRNLV
     IGSMRARRRK TLIWNSLQLK THSPFFLRIM DETTPLKIPL KVSNKIDTKS TFTPFTKIKQ
     GLIPFFSDSD DEKVFAAEKT ELDRLTIANK WDFASAHWGR GFPLVIQSYL RKYVVIPVLI
     ISKNISRILL FQVPEWKEDW NEWSKEIHVK CNYDGTEVSV HQLPSLWHRE GLQIKILYPF
     HLKPWHNSKL RQLEFLDNLD IKNFGDGDEI EKTLLYDGIK DSYTSAERKK IDYSYLTIWG
     NQTDSPFGNT KKQPFFWKPV IKELRKKRKR ILSKITQNFK IYYKFFPLGQ KSNIYNESDV
     PAVSKTRADK SKNNDIFEFE PDDKDKNEER DFKINNEIFD ELPIGITPKS SNNLSLQNSN
     KIEYGTGVFT RESGNDVTPN SNEIERITKH FFDEVQTNTD SKVISDEYPN DGKKLKLRKI
     LIKFYQQIIR LRRKSTQLIH ERINSINIFS EEINRNVLKN IFYLIRFKIK LMINFVKNIF
     INCNEVIHSY NNIFRLQTKY DKYVNQDLIV SGKEGQDPEF NSDQGIDSVS QADVFHGVRQ
     SKTINKSYLK NFLKYWNLYY FIGENYEKKL KVILDEKGIL GVGEPQNLSE ENWKDWLRCL
     HRCKLPSHIW CKIVPRTWKN EVTKHWKMEE NFPNHFDEDI PHTFMTYSSW ERIGKLNRRH
     KYNLLSYSYL DFAKNREIKK FPMWQSEGEQ TIFNNRIREI RECQSVNNEE NDKSKIYFEF
     KMKLWLFPEL MKAKKVFGSE VILIPEISLI AEKHNKSLKD ERLLEDRECH ESIYQWRRTS
     KELERIVKKL RDIAFLTIII ENQDKFVSLP ANIVENLEAL VFSTRGDSVK ETFQNLEFRL
     PRVLDDQILM YKTISTLLKF KNRFKRRLDL NTFDESIPRI EIVKNGGKTI SSSYFNLEDI
     LLPKRRMELR ILNSPDLKGD ENRDAELDRG TFGIKRQSYE QLIEEDRDSA NKNQIIKRFL
     RPSYRLEDPA CMNRFWFHTN NGSRFAMLRI CMYPSIHD