TI214_ILLOL
ID TI214_ILLOL Reviewed; 1882 AA.
AC A6MN03;
DT 08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 24-JUL-2007, sequence version 1.
DT 25-MAY-2022, entry version 37.
DE RecName: Full=Protein TIC 214 {ECO:0000250|UniProtKB:P56785};
DE AltName: Full=Translocon at the inner envelope membrane of chloroplasts 214 {ECO:0000250|UniProtKB:P56785};
DE Short=AtTIC214 {ECO:0000250|UniProtKB:P56785};
GN Name=TIC214 {ECO:0000250|UniProtKB:P56785}; Synonyms=ycf1;
OS Illicium oligandrum (Star anise).
OG Plastid; Chloroplast.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Austrobaileyales; Schisandraceae; Illicium.
OX NCBI_TaxID=145286;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=17644003; DOI=10.1016/j.ympev.2007.06.004;
RA Hansen D.R., Dastidar S.G., Cai Z., Penaflor C., Kuehl J.V., Boore J.L.,
RA Jansen R.K.;
RT "Phylogenetic and evolutionary implications of complete chloroplast genome
RT sequences of four early-diverging angiosperms: Buxus (Buxaceae),
RT Chloranthus (Chloranthaceae), Dioscorea (Dioscoreaceae), and Illicium
RT (Schisandraceae).";
RL Mol. Phylogenet. Evol. 45:547-563(2007).
CC -!- FUNCTION: Involved in protein precursor import into chloroplasts. May
CC be part of an intermediate translocation complex acting as a protein-
CC conducting channel at the inner envelope.
CC {ECO:0000250|UniProtKB:P56785}.
CC -!- SUBUNIT: Part of the Tic complex. {ECO:0000250|UniProtKB:P56785}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast inner membrane
CC {ECO:0000250|UniProtKB:P56785}; Multi-pass membrane protein
CC {ECO:0000255}.
CC -!- SIMILARITY: Belongs to the TIC214 family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; EF380354; ABQ52578.1; -; Genomic_DNA.
DR RefSeq; YP_001294329.1; NC_009600.1.
DR AlphaFoldDB; A6MN03; -.
DR PRIDE; A6MN03; -.
DR GeneID; 5236707; -.
DR GO; GO:0009706; C:chloroplast inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR InterPro; IPR008896; TIC214.
DR PANTHER; PTHR33163; PTHR33163; 1.
DR Pfam; PF05758; Ycf1; 1.
PE 3: Inferred from homology;
KW Chloroplast; Membrane; Plastid; Plastid inner membrane; Protein transport;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..1882
FT /note="Protein TIC 214"
FT /id="PRO_0000326576"
FT TRANSMEM 18..38
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 64..84
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 87..107
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 124..144
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 172..192
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 221..241
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 246..308
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 779..800
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1578..1626
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 265..280
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 287..308
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1578..1614
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1882 AA; 224217 MW; 59567767B4164B0F CRC64;
MILKSFLLGN LLSLCMKIIN SVVVVGLYYG FLTTFSIGPS YLFLLRARVM EEGTEKEVSA
TTGFITGQFM MFISIYYAPL HLALGRPHTI TVLVLPYLLF HFFWNNHKHF FDYGSTTRNS
MRNLSIQCVF LNNLSFQLFN HFILPSSTLA RLVNIYMFRC NNKMLFVTSS FVGWLIGHIL
FMKWVGLVLF WIRQNHSIRS NVLIRSNKYL VSELRNSMAR IFSILLFITC VYYLGRIPSP
IVTKKLKETS ETEEGEETEE EGDVKIETTS ETKGTEQEQK GSTEEGPSLC SEEKEDPDKI
DETEEIRVNG KEKTKDELDF RFQETWYNHS TVYDNDISDS YGDQEDWELE ILKLKDKQLF
WFEKPLVTLL FDYLRWNRPL RYINNNDRFP NAVRNEMSQY FFDTSKRDGN KIISFTYPPS
LSIFNEMIQK KIFLSTTEKL SPEGLYNHYN YWIYANEQKK YNLNNEFINR IEALDKGSLV
LDVLEQKNRL CNDENEQECL PKMYDPFLNG PYRGRIKKYY LHSIRNDSIT STGDSVETVW
INRIHDILPT YREFGHKMNI FDGESLSTDI DDSLISIGEL AEESASSLKL LALLAEQRGI
DSENKMRYLS FPFDRVTTDP NNQTIRNEAI GLEEIGKRVP RWLYRLTEDL EEQEDEDLEE
STEDHGIRSR KAKRVIIFAD NDNNTNTNTH TSTENTINSD QGEELTLLRY SQKSDFRRNL
IKGSMRAQRR KTVTWEMFQI NVHSPLFLDR IDKTFSFSFD ISRMMNLIFR NRIGKDPEFQ
TSDSEKARVK EEDKKEEHKK KEDERITIAE LFDTIIFAQA IRGSMLVIQS ILRKYIILPS
LIIAKNIGRM LLFQFPEWYE DWKAWSKEMH VKCTYNGVQL SETEFPKDWL TDGIQIKILF
PFCLKPWRRS KLGSHHIDRM KKKEKKDNFC FLTIWGMEAE LPFGSPRKRP SFFKPIWKEF
QQKITKVKKK RFLFLRVFKK RTKGFLKISK EKTRWVIKIV LFIKKKMKEL TKETLIVLFG
LRKVYEPNEN RKDSIISDKI TPESSLRVGS MDWTNYSLTE KKMKDLADRT TPIRDQIERI
TKDKKDNFIT PNINISPNER SCGDKRPELQ KHIWKVFKKG SARLIPKWNY FMKSFIQRIY
IDIFLYAINM PRVNAQLFLE LRIRKKMIDK YIYNDETNQE GIDETNQNTI HFISTIKSLS
NITNISHSNI SNNNSQIYCD LSSLSQAYVF YILSQTQVLN KYYLKSLFQH DGEYPFIKDK
IKDYFLTRGI FHSESRYKQL PNCRMNEWKN WLRGHYQYNL SHTRWSRLVP RKWRNGVNQH
HRIKQHHRIK KKNSKKWDSY EKDQLIHYEK DNSYAVDSLP SPKKKMEKHY KYDLLSHKYI
NYGYRKDSYI YGSPLQINGD REIPYNYNTH KSEPFYVPGD IAISDYLGEE YIIGTDKNPD
RKYLDWRIIH FCLRNNKNIN IETWGNMNTE IDANKNTKIG TNDYQIINKK GIFYLTTHQE
INPRNQKKNL FDWMGMNQEI LYRPRSNLKS WFFPEFMRLY EAYKTKPWII PTQLLIFHFD
GNQKKDLHIS YNQKEHLELE TQNQEEKKRQ DKKNPGSDAQ NQKDVEEDST RSDSKKRSKK
KKPKSKSNKE AELDFFLKRY FLFQLRWDDP LNQKRINNIK VYCLLLRLMD PKEIALASIQ
RGEMCLAAMK IQKDLAVTEL IKKGILILEP VRLSIKWDGQ FIMYQTIGIS LVHKSKHKTN
RRCREKRYVD ENYFDISIEQ HGKMLVNRDK KNYDLLVPEN ILSLRRRREL RILIRFNSEN
RNIVNRNPVF LNGNGSHNCE QFVDRDKHLD TDTNKFIKWK LFIWPNYRLE DLACMNRYWF
DTNNGSHFSM SRIYMYPRFR IS
