ID   TI214_LEPVR             Reviewed;        1734 AA.
AC   A4QLG7; A4QLF5;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   15-MAY-2007, sequence version 1.
DT   25-MAY-2022, entry version 33.
DE   RecName: Full=Protein TIC 214 {ECO:0000250|UniProtKB:P56785};
DE   AltName: Full=Translocon at the inner envelope membrane of chloroplasts 214 {ECO:0000250|UniProtKB:P56785};
DE            Short=AtTIC214 {ECO:0000250|UniProtKB:P56785};
GN   Name=TIC214 {ECO:0000250|UniProtKB:P56785}; Synonyms=ycf1-A;
GN   and
GN   Name=TIC214 {ECO:0000250|UniProtKB:P56785}; Synonyms=ycf1-B;
OS   Lepidium virginicum (Virginia pepperweed).
OG   Plastid; Chloroplast.
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Lepidieae; Lepidium.
OX   NCBI_TaxID=59292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Hosouchi T., Tsuruoka H., Kotani H.;
RT   "Sequencing analysis of Lepidium virginicum JO26 chloroplast DNA.";
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in protein precursor import into chloroplasts. May
CC       be part of an intermediate translocation complex acting as a protein-
CC       conducting channel at the inner envelope.
CC       {ECO:0000250|UniProtKB:P56785}.
CC   -!- SUBUNIT: Part of the Tic complex. {ECO:0000250|UniProtKB:P56785}.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast inner membrane
CC       {ECO:0000250|UniProtKB:P56785}; Multi-pass membrane protein
CC       {ECO:0000255}.
CC   -!- MISCELLANEOUS: There is a partial copy of the N-terminus (positions 1-
CC       302) of ycf1 in the inverted repeat (BAF50510).
CC   -!- SIMILARITY: Belongs to the TIC214 family. {ECO:0000305}.
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DR   EMBL; AP009374; BAF50522.1; -; Genomic_DNA.
DR   EMBL; AP009374; BAF50510.1; -; Genomic_DNA.
DR   RefSeq; YP_001123685.1; NC_009273.1.
DR   RefSeq; YP_001123697.1; NC_009273.1.
DR   AlphaFoldDB; A4QLG7; -.
DR   PRIDE; A4QLG7; -.
DR   GeneID; 4962024; -.
DR   GeneID; 4962046; -.
DR   GO; GO:0009706; C:chloroplast inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR008896; TIC214.
DR   PANTHER; PTHR33163; PTHR33163; 2.
DR   Pfam; PF05758; Ycf1; 2.
PE   3: Inferred from homology;
KW   Chloroplast; Coiled coil; Membrane; Plastid; Plastid inner membrane;
KW   Protein transport; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..1734
FT                   /note="Protein TIC 214"
FT                   /id="PRO_0000326579"
FT   TRANSMEM        19..39
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        68..88
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        91..111
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        133..153
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        176..196
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        227..247
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   COILED          1433..1485
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   1734 AA;  206809 MW;  F2AFC763B29BE893 CRC64;
     MMVFQSFILG NLVSLCMKII NSVVVVGLYY GFLTTFSIGP SYLFLLRARV MDEGEEGTEK
     KVSATTGFIA GQLMMFISIY YAPLHLALGR PHTITVLALP YLLFHFFWNN HKHFLDYGST
     TRNEMRNLRI QCVFLNNLIF QLFNHFILPS SMLARLVNIY MFRCNNKMLF VTSSFVGWLI
     GHILFMKWVG LVLVWIQQNN SIRSNVLIRS NKYKFLVSEL RNSMARIFSI LLFITCVYYL
     GRMPSPIFTK KLKGTSETEE RGGTKQDQEV SIEEAPFPSL FLDGNKENSN LEFFKIKKKE
     DYCLWFEKPF VTLVFDYKRW NRPNRYIKND KIENTVRNEM SQYFFYTCQS DGKERISFTY
     PPSLSTFFEM IQKKIPSFTR EKTASTQVST YWSLINEEKK ENLKKELLNR IEALDKGWSV
     ENILEKTTRF CHNETKKEYL PKIYDPSLHG ISRGRIKKLP PFKIITETYI TNNIGGSWIN
     KIHGILLKIN YQKFEQTLEK FNRKSLSIEK KLYFFSEPQE EKIHSEEELK IFKFLFNVVR
     TDSNDQTLNR TNFIDFHEIT KKVPRWSYKL IGELEELEGE NEDNVPMEPG IRSRKGKRVV
     IFTDNQNSDQ NDEMALIRYS QQSDFRREII KGSMRSQRRK TVIWEFFQAK VHSPLFFDRI
     DKLFLFSFDI RGLKKKILRN FMWKNKKKKK IDKKEEEQSK IEEKRRIEIA ETWDSFLFAQ
     IIRGFLLITQ SILRKYIILP LLIIMKNSVR MLLFQIPEWS EDLKDWKREM HVKCTYNGVQ
     LSETEFPRNW LTDGIQIKIL FPFYLKPWHK SKFQSSQKAR LKKTKAKGEK NAFCFLTVWG
     METELPFGSA QRKPSFFQPI SKELKKRIKK LKTKPFLVLG IFKERATICL KVAKEIKNWI
     LKNSLFIKVK RKNLSKPNKI PVFGPREIFE LNETKKDSIM SNQMIYELSV QNKSMEWRNS
     SLSENKIKNL IDRIKTIRNQ IEEISKEKEN LTNSCNKLRY DSKIIESAKR IWQIFKRKNT
     RFIRKSIFFI KFCIEQLSIA IFLGISNIPR ITTQLFFEST KTILNKYIYK NEEKVEKINK
     KKNTIYFIST IKNLISNKKK ISYDLCSLSQ AYVFYKLSQI QVSNFSKLKA VLEYNICITS
     FFVKNQIKDF FQEQGIFHYE LKDKTFFNSE VNQWKNWLRS HYQYNLPQVA WARLVTQKWK
     TKITQDSLVL NPSLTKEDSY EKKKFDNSKK DNFFEANLLL NPKHNLKKDS IYNLFCYKSI
     NSTEKKFDMS IGIALDNCLV SCFLEKYNIR GTGEIRHRKY LDWRILNFWF TKKVNIEPWV
     DTKSKKKYIN TKVQNYQRID KITKTSLANQ KRNFFDWMGM NEEILNPCIT NFEFFFFPEF
     LLFSSTYKTK PWVIPIKLLL FNFNENINVN KKITRKKTSF IPSNENKSLL FYNLNNEEKE
     LADEVELESD NEKQINPESA LSNQEKTIQE IYAESKKKKR QNKKQSKSNT EVELDLFLTR
     HSRFQLRWNC FFNQKILNNV KVYCLLIRLK NPNEIAISSI ERGEMSLDIL MIEKNFTLAK
     LMKKGILIIE PVRLSVQNNG QLIIYRTIGI SLVQKNKHKI SKRYKKKIEK SITKYQKKTV
     NRKKNHYDFF VPENILSPKR RREFRILICF NLKKKNASDR NSRFDKNIQN LTTVLHKKKD
     LDKDQNNLIK FKSFLWPNFR LEDLACMNRY WFNTTNGNHF SMIRIHMYTR FPIH