ID   TI214_LIRTU             Reviewed;        1835 AA.
AC   Q0G9G1;
DT   28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT   03-OCT-2006, sequence version 1.
DT   25-MAY-2022, entry version 36.
DE   RecName: Full=Protein TIC 214 {ECO:0000250|UniProtKB:P56785};
DE   AltName: Full=Translocon at the inner envelope membrane of chloroplasts 214 {ECO:0000250|UniProtKB:P56785};
DE            Short=AtTIC214 {ECO:0000250|UniProtKB:P56785};
GN   Name=TIC214 {ECO:0000250|UniProtKB:P56785}; Synonyms=ycf1;
OS   Liriodendron tulipifera (Tuliptree) (Tulip poplar).
OG   Plastid; Chloroplast.
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; Magnoliidae; Magnoliales; Magnoliaceae;
OC   Liriodendron.
OX   NCBI_TaxID=3415;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=17020608; DOI=10.1186/1471-2148-6-77;
RA   Cai Z., Penaflor C., Kuehl J.V., Leebens-Mack J., Carlson J.E.,
RA   dePamphilis C.W., Boore J.L., Jansen R.K.;
RT   "Complete plastid genome sequences of Drimys, Liriodendron, and Piper:
RT   implications for the phylogenetic relationships of magnoliids.";
RL   BMC Evol. Biol. 6:77-77(2006).
CC   -!- FUNCTION: Involved in protein precursor import into chloroplasts. May
CC       be part of an intermediate translocation complex acting as a protein-
CC       conducting channel at the inner envelope.
CC       {ECO:0000250|UniProtKB:P56785}.
CC   -!- SUBUNIT: Part of the Tic complex. {ECO:0000250|UniProtKB:P56785}.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast inner membrane
CC       {ECO:0000250|UniProtKB:P56785}; Multi-pass membrane protein
CC       {ECO:0000255}.
CC   -!- SIMILARITY: Belongs to the TIC214 family. {ECO:0000305}.
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DR   EMBL; DQ899947; ABI32567.1; -; Genomic_DNA.
DR   RefSeq; YP_740260.1; NC_008326.1.
DR   AlphaFoldDB; Q0G9G1; -.
DR   GeneID; 4266692; -.
DR   GO; GO:0009706; C:chloroplast inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR008896; TIC214.
DR   PANTHER; PTHR33163; PTHR33163; 1.
DR   Pfam; PF05758; Ycf1; 2.
PE   3: Inferred from homology;
KW   Chloroplast; Membrane; Plastid; Plastid inner membrane; Protein transport;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..1835
FT                   /note="Protein TIC 214"
FT                   /id="PRO_0000262614"
FT   TRANSMEM        25..45
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        64..84
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        87..107
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        124..144
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        172..192
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        221..241
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          246..304
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          735..759
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1535..1578
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        266..283
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        736..759
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1554..1571
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1835 AA;  218305 MW;  01B4E5AD82C9A158 CRC64;
     MILKSFLLGN LLSLCMKIIN SVVGVGLYYG FLTTFSIGPS YLFLLRARVM EEGTEKEVSA
     TTGFITGQLM MFISIYYAPL HLALDRPHTI TVLVLPYLLF HFFWNNHKHF FDYGSTTRNS
     MRNLSIQCVF LNNLIFQLFN HFILPSSTLA RLVNIYMFRC NNKMLFVTSS FVGWLIGHIF
     FMKWVGLVLF WIRQNHSIRS NVLIRSNKYL VSELRNSMAR IFSILLFITC VYYLGRIPSP
     IVTKKLKETS ETEERGESAE ETDVEIETTS ETKGTKQEQE ASTEEDPSLC SEEKEDPDKL
     DGNQGYQENW KLEILKDKDL FWFEKPLVTL LFDYKRWNRP LRYIKNDRFE KTVRNEMSQY
     FFHTCPSDGK KRISFTYPPS LSTFGEIIQR KMSLYTTDKL LSPEDPYNHW VYTNEQKRHN
     LSNEFINRIE ALDRGTLTLD VLEKSTRLCN NENEQEFFPK IYDPFLNGPY RGTTKKVYSR
     SIMDDSITWT EDSIEMVWIN KIHDIFPNDY REFEQKMDLF NGESLSTDIG HSLTSINKFA
     GESAPNLNLK GLALLAEQRR LDSENQTKCL KFLSDVVTTD PNDQTIQNKY IGIEEIGKKV
     PRWSYKLTDH LEEQEKENEE ESTEDHGIRS RKAKRVVIYT DNDQNTNTYT STSTNSDQAE
     ELALIRYSQQ SDFRRDLIKG SMRAQRRKTV TWEMFQANVH SPLFLDRIDK TFFFSFDISG
     MMNLIFRNWV GKGPEFKTSD SEEKEAKEKE KTKEEKKEEN ERIAIAETWD TIIFAQAIRG
     SMLVTQSILR KYIVLPSLII AKNLGRMLLF QFPEWYEDWK EWNREMHVKC TYNGVQLSET
     EFPKDWLTDG IQIKILFPFC LKPWHRSKLR SHHRDRMKKK GKKENFCFLT VWGMETELPF
     GSSRKRPSFF EPICKELEKK IRKVKKKCFL VLRALGERTK WFLRVLKEKT RWILKTVLFI
     KRIIKEFAKV NPILLFGLRK VYEPNENRKD SITNNKINHE SIIRIRSVDW TNYSLTEKKM
     KDLADRTTTI RNKIERITKD KRKIFLTPDI KISPNETGCD DKRSESQKHI WQISKRRSAR
     LIRKWHYFMK SFIERIYMDI FLCTINIPRR NAHLFLESTK KIIDKDIYND ERNKEGIDET
     NQNAIHFIST IKKSLSNISN NKSQIYCDLS SLSQAYVFYN LLQIQVINKY YLRFVLQYRG
     AYLFLKDRIK DHFGTRGILD AKSRPKKPPN SGMNEWKNWL RGHYQYNLSQ TRWSRLVPQK
     WRNRVNQRRT IQNKDSKKDS YEKDQFIHYE KQNNYVVNSL PNKKEKFKKH YRYDLLSHKY
     IHYEDRKDSY IYGSPLQVNV NGDREIPYNY NTPKPESFYV PRGIAISDYL GEESIIDTGK
     NPDRKYLEWR ILNFFLRKNI DIETWIDIDT GTNINKNAKT GTNDYQIIDK KDLFYLPIHQ
     EINPSNQKQG FFFDWMGMNE EMLYRPISNL EPWFFSEFVL LYDAYKIKPW IIPIKLLIFN
     LNGNENISEN KNINRNQKKD LRLSSNQKEY LELENRNQEE KEQLGQGNLG SDPRNRQKDL
     EKDYAESDIK KRRKKRQSKS NKEAELNFFL KRYLLFQLRW DDPLNQRMIN NIKVYCLLLR
     LINPKEIAIS SIQRGEMRLD VMLIQKDLTL TELIKRGILI IEPVRLSIKW DGQWIMYQTI
     GISLVHKNKY QTNRICREKK YVDENSFDRS IAQHGKVLVN GDENNYALLV PENIPSPRRR
     RELRILICLN SENGNVVDRN SVFFNGNNVR NCVQFLDEDK HFDTDINKFI QFKLFLCPNY
     RLEDLACMNR YWFDTNNGSR FSMSRIHMYP RFRIS