ID   TI214_LOBMA             Reviewed;        1775 AA.
AC   A4QLQ5; A4QLP3;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   15-MAY-2007, sequence version 1.
DT   25-MAY-2022, entry version 37.
DE   RecName: Full=Protein TIC 214 {ECO:0000250|UniProtKB:P56785};
DE   AltName: Full=Translocon at the inner envelope membrane of chloroplasts 214 {ECO:0000250|UniProtKB:P56785};
DE            Short=AtTIC214 {ECO:0000250|UniProtKB:P56785};
GN   Name=TIC214 {ECO:0000250|UniProtKB:P56785}; Synonyms=ycf1-A;
GN   and
GN   Name=TIC214 {ECO:0000250|UniProtKB:P56785}; Synonyms=ycf1-B;
OS   Lobularia maritima (Sweet alyssum) (Alyssum maritimum).
OG   Plastid; Chloroplast.
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Anastaticeae; Lobularia.
OX   NCBI_TaxID=226051;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Hosouchi T., Tsuruoka H., Kotani H.;
RT   "Sequencing analysis of Lobularia maritima chloroplast DNA.";
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in protein precursor import into chloroplasts. May
CC       be part of an intermediate translocation complex acting as a protein-
CC       conducting channel at the inner envelope.
CC       {ECO:0000250|UniProtKB:P56785}.
CC   -!- SUBUNIT: Part of the Tic complex. {ECO:0000250|UniProtKB:P56785}.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast inner membrane
CC       {ECO:0000250|UniProtKB:P56785}; Multi-pass membrane protein
CC       {ECO:0000255}.
CC   -!- MISCELLANEOUS: There is a partial copy of the N-terminus (positions 1-
CC       343) of ycf1 in the inverted repeat (BAF50598).
CC   -!- SIMILARITY: Belongs to the TIC214 family. {ECO:0000305}.
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DR   EMBL; AP009375; BAF50610.1; -; Genomic_DNA.
DR   EMBL; AP009375; BAF50598.1; -; Genomic_DNA.
DR   RefSeq; YP_001123773.1; NC_009274.1.
DR   RefSeq; YP_001123785.1; NC_009274.1.
DR   AlphaFoldDB; A4QLQ5; -.
DR   GeneID; 4964825; -.
DR   GeneID; 4964889; -.
DR   GO; GO:0009706; C:chloroplast inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR008896; TIC214.
DR   PANTHER; PTHR33163; PTHR33163; 1.
DR   Pfam; PF05758; Ycf1; 1.
PE   3: Inferred from homology;
KW   Chloroplast; Membrane; Plastid; Plastid inner membrane; Protein transport;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..1775
FT                   /note="Protein TIC 214"
FT                   /id="PRO_0000326580"
FT   TRANSMEM        19..39
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        68..88
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        91..111
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        133..153
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        176..196
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        227..247
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          1491..1512
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1775 AA;  211942 MW;  8B460D53CE8FC9BC CRC64;
     MMVFQSFILG NLVSLCMKII NSVVVVGLYY GFLTTFSIGP SYLFLLRARV MDEGEEGTEK
     KVSATTGFIA GQLMMFISIY YAPLHLALGR PHTITVLALP YLLFHFFWNN HKHFFDYGST
     TRNEMRNLRI QCVFLNNLIF QLFNHFILPS SMLARLVNIY MFRCNNKMLF VTSSFVGWLI
     GHILFMKWVG LVLVWIQQNN SIRSNVLIRS NKYKFLVSEL RNSMARIFSI LLFITCVYYL
     GRIPSPIFTK KLKGTSERGG TKQDQEVSTE EAPFPSLFSE EREDLDKIDE MEQIRVNGKE
     KINKDDEFHV RTYYNSKTVS ENRDGNKENS NLEFFKIKKK EDCFLGFAKP FVTLVFDYKR
     WNRPNRYIKN DKIEHTVRNE MSQYFFYTCQ NDGKEQISFT YPANLSTFFE MMQKKIPPFT
     REKAPSDQVF TCWSLINEEK KENLQNEFFN RIETLDKEWS VENILEKTTR FCHNETKTEY
     LPKIYDPFLH GISRGRIKKL PPFQIITETY IKNNIGGSWI NKIHGILLKI NSRKFEQTLE
     KFNRKSLSIE EKLSCFSEPQ EEQNNSEEEI KIFKFLFNVV ITDNNEQTFI KNLIYFDEIN
     KKVPRWSYKL ISDLEEMEAE DEQSILAEPG IRSRKAKRIV VFTEKETHNE TFKENQSSDE
     KEEISFIRFS QQPDFRREII KGSMRSQRRK TVIWEFFQAK AHSPFFFDRI DKLFFFSFDS
     FSFDIWGLKK KILRNFMWKN KTIYKTKAEQ SKIEEKKRLQ IAETWDNVRF AQIIRSSVLV
     TQSILRKNII LPLLIIIKNS IRVLLFQIPE WSEDLKDLKR EMHVKCTYNG VQLSEKEFPR
     KWLTDGIQIK IIFPFYLKPW HNSKFQSSQK AQRKKAKDTE KKNDFCFLTV WGRETELPFG
     SAKKKPSFFE PIYKELKKRI KKFKTKPFLV LRIFKEREKF FLKVAKEMKN WIIKNFLFLK
     GKIKNLSKRN IIPVFGPREI YEVNETKNDS IMSNQMIENL SVQKKSMEWT NSLLSENKLK
     NLIDRIKTIR NQTEEISKEK ENLTNSCNKP RYDSKIIESS KKSWQTLKRK NTRLIRKSFF
     FIKFCIEQLS IAIFLGIINI PRITTQLFFE STKTILDKYI YKNEENGKKI NKKKTTIYFI
     STIKNLLSKK KKISYDLCSL SQAYVFYKLS KMQVSNVSKL KAVLEYKICI TSFFVKNKIK
     DFFQEQGIFD YELKDKTFVN SEVNQWKNWL RSHSQYNLPQ IAWARLGTQK WKNKINQDSI
     VLNRSLTKED SYEKKIFDNY KKQNFFEADS LLNPKHNVKK DYIYNLFCYK SINSTEKNLD
     MAIGIALDNY LVSCFLEKYN IRGRRKIGHR KYLDWRMLNF WFRKNVNSEP WVDTKSKKKY
     IKTQVQNYQR IEKITKTGVA NEKNFFFDWM GMNEEIINNR VTNLEFFFFP EFLLFSSTYK
     MKPWVIPIKL LLFNFNEKKN INKKITPNKK GFIPSNAKKF LEFFNLNKEE KESAGQGERE
     SDNEKKKNLE SALSKQEKNI EENYAELKIK KHKTKKQHKS NTEVEIDSFM GRDSRFQMRW
     NSFFNKKIIT TLKVYCFLVR LKNPNEIILS SIERGEINPD ILLISKTLPF SQLLKKGMWV
     FEPVRLSLKN DGQLIIYRTI GISLVHKKKN KISKRYKKKS YIDKKNNCDF FVPENILSPK
     RRREFRILIC FNLKKKNARD RNSRFDKNIP NLTTVLHKKK NLDKDKNNLI KLKSFLWPNF
     RLEDLACMNR YWFNTTNGNH FGMIRIHMYT RFQIH