TI214_NANDO
ID TI214_NANDO Reviewed; 1843 AA.
AC Q09FQ2;
DT 28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT 17-OCT-2006, sequence version 1.
DT 25-MAY-2022, entry version 34.
DE RecName: Full=Protein TIC 214 {ECO:0000250|UniProtKB:P56785};
DE AltName: Full=Translocon at the inner envelope membrane of chloroplasts 214 {ECO:0000250|UniProtKB:P56785};
DE Short=AtTIC214 {ECO:0000250|UniProtKB:P56785};
GN Name=TIC214 {ECO:0000250|UniProtKB:P56785}; Synonyms=ycf1;
OS Nandina domestica (Heavenly bamboo).
OG Plastid; Chloroplast.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Ranunculales; Berberidaceae; Nandinoideae;
OC Nandina.
OX NCBI_TaxID=41776;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16934154; DOI=10.1186/1471-2229-6-17;
RA Moore M.J., Dhingra A., Soltis P.S., Shaw R., Farmerie W.G., Folta K.M.,
RA Soltis D.E.;
RT "Rapid and accurate pyrosequencing of angiosperm plastid genomes.";
RL BMC Plant Biol. 6:17-17(2006).
CC -!- FUNCTION: Involved in protein precursor import into chloroplasts. May
CC be part of an intermediate translocation complex acting as a protein-
CC conducting channel at the inner envelope.
CC {ECO:0000250|UniProtKB:P56785}.
CC -!- SUBUNIT: Part of the Tic complex. {ECO:0000250|UniProtKB:P56785}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast inner membrane
CC {ECO:0000250|UniProtKB:P56785}; Multi-pass membrane protein
CC {ECO:0000255}.
CC -!- SIMILARITY: Belongs to the TIC214 family. {ECO:0000305}.
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DR EMBL; DQ923117; ABI49923.1; -; Genomic_DNA.
DR RefSeq; YP_740709.1; NC_008336.1.
DR AlphaFoldDB; Q09FQ2; -.
DR PRIDE; Q09FQ2; -.
DR GeneID; 4271657; -.
DR GO; GO:0009706; C:chloroplast inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR InterPro; IPR008896; TIC214.
DR PANTHER; PTHR33163; PTHR33163; 3.
DR Pfam; PF05758; Ycf1; 3.
PE 3: Inferred from homology;
KW Chloroplast; Membrane; Plastid; Plastid inner membrane; Protein transport;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..1843
FT /note="Protein TIC 214"
FT /id="PRO_0000262616"
FT TRANSMEM 18..38
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 64..84
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 87..107
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 124..144
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 172..192
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 217..237
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 244..281
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 557..576
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 582..647
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 724..744
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1527..1586
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 263..281
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 583..647
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1527..1543
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1544..1562
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1563..1586
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1843 AA; 218672 MW; 7968EE02B02A6BAD CRC64;
MIFNSFLLGN LLSLCMKIIN SVVVVGLYYG FLTTFSIGPS YLFLLRARVM EEGTEKEVSA
TTGFITGQLM MFISIYYAPL HLALGRPHTI TVLVLPYLLF HFFWNNHKHF FDYGSTTRNS
MRNLSIQCVF LNNLIFQLFN HFILPSPTLA RLVNIYMFRC NNKMLFVTSS FVGWLIGHIL
FMKWVGLVLF WIRQNRSIRS NKYLVSELRN SMARIRIFSI LLFITCVYYL GRIPSPIVTK
KLKETSKTEE REESEEETDV EIETTSETKG TKQEQEGAAE KEVKDDKDLF WFEKPLVTLL
FDYKRWNRPL RYIKNERFEN AVRNEMSQYF FYTCISDGKQ RISFTYPPSL STFFEMIQKK
LFLCTTEKIS SEELYNHWAY TNEQKRNNLS KEFINRIETL DEGSLDLDIL EKKTRLCNDE
NEQKCLPKIY DPFLNGPHRG TIQNLYSHSS MNNLLITSIK DSIKTLWINK YQGILDTDCR
EFEKEFAEEP MPNLNLKSPS SQGKFYSENQ SKNFFDAATT YPNDQTIIDI EESLEINEIK
KTVPRWLYKL TDDLEEEEIE NDEESKPDHG IRSRKAKRVV IFTDNEKNQN TPTSTTETTS
TAETTSTTET TSTTKNTSTT KNTSTTETTS TTENENTSNQ DQSDEVALTR YSQQPDFRRD
LIKGSMRAQR RKTVTWELFQ ATVRSPLFLD RVDKTFFFSF DISGTLKYFF RNWMGKDAEF
KISNSEEEDT KEKEKKREEK RQENERIRIS ETWDTIIFAQ AIRGYMLVTQ SILRKYIVLP
SLIIAKNIGR MLLFQFPEWH EDLKAWNKEM HVKCTYNGVQ LSEKEFPKNW LTDGIQIKIL
FPFCLKPWHR SKVQFDHRDP MKKKGKPENF CFLTVWGMEA ELPFGSPRKR PSFFEPIWKE
IEKNIIKMKK KCFIALRILK ERTKWFIRVS KEKTRWVIKI FLFIKRIMKE LAKAKVSPIP
LFGLREIDES SINTNQKYYI NIKSNQIIHE SPIRIRSLDW INYSLTAKKI KDVVDRTSTI
RNQIEKITKD KKKLFLTPDR NINPNKIGCD DKGLESLKKI WQKLKRRSNR LIRKCYYFLK
FFIERIYTDI LFCIINSLRI KVKLFLEAKN KLFYKNSSND ETNKKGIDET NPNTIHFIST
IKKSLSNINN SNNNSQIFCD LDSLSQAYVF YKLSQTQVFN KYHLRSVLQY RGTLLFLKDR
IKDSFGTQGI FHSESGHKKL RNFRMNEWKN WLRGRYHYQY DFSQTRWSRL VPQKWRNRIH
QRCMVQTKNS TYSDLYEKDQ LIHYEKQNNY AVELNQKDKF KNYKYDKYDR LSHKYIHYED
KKDSYIYRSP LQVNEAKEFL YNYNTYNYST YNPKLFFMSG DISLNNYLRE DSDTEKNLDR
KYFDWKIFNF CLRTKIDIEY WTNMDIGANV NKKTKTQTNY YQIIDKKDLF SIAIHKQINP
AKQTKTSFDW MAMNEEILNC PISNLELWFF PEFVSFYNAY KIQPWTIPIN LLLLNFNGNE
NVSEKQNING KEKKDLPILS KSNQKKSLEL KNKEEKKKPA QENIGSDTQK QGNPGSDPST
QQKDIKKNVK EDYDGRSDIQ KRKKKKQSTG NIAAELDLFL KRYFLFQLRW DNPLNKKIIN
NVKVYCLLLR LKNPKEIAIA SIQRDEMSLD VMPISKTLTL AKLINKGMLI IEPARLSIKR
DGQFLLYQTI TISRVHKNKH QTNQRYQEKR NVDKNGLEKS IARHEKLVGN RDKNPLLVLE
NILSSQRRRE LRIRICLNSG NVNVVDRNPV FCNGNNASNC DQFLNEERHL DIDTNKFLKF
KLLLWPNYRL EDLACINRYW FDTNNGSRFS MSRIRMYPQL RIS
