ID   TI214_NASOF             Reviewed;        1802 AA.
AC   A4QLZ3; A4QLY1;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   15-MAY-2007, sequence version 1.
DT   25-MAY-2022, entry version 36.
DE   RecName: Full=Protein TIC 214 {ECO:0000250|UniProtKB:P56785};
DE   AltName: Full=Translocon at the inner envelope membrane of chloroplasts 214 {ECO:0000250|UniProtKB:P56785};
DE            Short=AtTIC214 {ECO:0000250|UniProtKB:P56785};
GN   Name=TIC214 {ECO:0000250|UniProtKB:P56785}; Synonyms=ycf1-A;
GN   and
GN   Name=TIC214 {ECO:0000250|UniProtKB:P56785}; Synonyms=ycf1-B;
OS   Nasturtium officinale (Watercress) (Rorippa nasturtium-aquaticum).
OG   Plastid; Chloroplast.
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Cardamineae; Nasturtium.
OX   NCBI_TaxID=65948;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Hosouchi T., Tsuruoka H., Kotani H.;
RT   "Sequencing analysis of Nasturtium officinale chloroplast DNA.";
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in protein precursor import into chloroplasts. May
CC       be part of an intermediate translocation complex acting as a protein-
CC       conducting channel at the inner envelope.
CC       {ECO:0000250|UniProtKB:P56785}.
CC   -!- SUBUNIT: Part of the Tic complex. {ECO:0000250|UniProtKB:P56785}.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast inner membrane
CC       {ECO:0000250|UniProtKB:P56785}; Multi-pass membrane protein
CC       {ECO:0000255}.
CC   -!- MISCELLANEOUS: There is a partial copy of the N-terminus (positions 1-
CC       343) of ycf1 in the inverted repeat (BAF50686).
CC   -!- SIMILARITY: Belongs to the TIC214 family. {ECO:0000305}.
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DR   EMBL; AP009376; BAF50698.1; -; Genomic_DNA.
DR   EMBL; AP009376; BAF50686.1; -; Genomic_DNA.
DR   RefSeq; YP_001123861.1; NC_009275.1.
DR   RefSeq; YP_001123873.1; NC_009275.1.
DR   AlphaFoldDB; A4QLZ3; -.
DR   PRIDE; A4QLZ3; -.
DR   GeneID; 4962099; -.
DR   GeneID; 4962156; -.
DR   GO; GO:0009706; C:chloroplast inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR008896; TIC214.
DR   PANTHER; PTHR33163; PTHR33163; 1.
DR   Pfam; PF05758; Ycf1; 1.
PE   3: Inferred from homology;
KW   Chloroplast; Membrane; Plastid; Plastid inner membrane; Protein transport;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..1802
FT                   /note="Protein TIC 214"
FT                   /id="PRO_0000326581"
FT   TRANSMEM        19..39
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        68..88
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        91..111
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        133..153
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        176..196
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        227..247
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   1802 AA;  215649 MW;  9EA2CAC6752F946B CRC64;
     MMVFQSFILG NLVSLCMKII NSVVVVGLYY GFLTTFSIGP SYLFLLRARV MDEGEEGTEK
     KVSATTGFIA GQLMMFISIY YAPLHLALGR PHTITVLALP YLLFHFFWNN HKHFFDYGST
     TRNEMRNLRI QCVFLNNLIF QLFNHFILPS SMLARLVNIY MFRCNNKMLF VTSSFVGWLI
     GHILFMKWVG LVLVWIQQNN SIRSNVLIRS NKYKFLVSEL RNSMARIFSI LLFITCVYYL
     GRIPSPIFTK KLKGTSETGG TKQDQEVSTE EAPFPSLFSE EREDLDKIDE MEEIRVNGKD
     KINKDDEFHV RTYYNYKTVS ENLDGNKENS NLEFFKIKKK EDHFLWFEKP FVTLVFDYKR
     WNRPNRYIKN EKIQNTVRNE MSQYFFYTCQ SDGKERISFT YPPTLSTFFE MIQKNIPSFT
     REKTPSDQVS TYWRLINEEK KENLKKEFLN RIEALDKEWS VENILEKTTR FCHNETKKEY
     LPKIYDPFLH GVSRGRIKKL PQFQIITETY IKKNIEGSWI NKIHGILMKM NSNKFEQTIE
     KFNIESLSIE KKLSFFSESQ EEKINSEEEI KIFKFLFDVV ITDSNDQTLI KNFMDFHEIN
     KKVPRWSYKL ISELEELEGE NEENVTMEPG IRSRKAKRVV VFTDTEPHNE VYTKLKDLKD
     NQNSDQNDEM ALIRYSHQSD FRRELIKGSM RSQRRKTVIW QFFQAKVHSP LFFDRIDKLF
     YFSFDIWGLK KEILRNFMWK NKKNQKIDKK DEEQSKIEEK RRIEISETWD SFLFAQIIRG
     YLLVTQSILR KYIILPLLII IKNSVRMLLF QFPEWSEDLK DWKREMHVKC TYNGVQLSET
     EFPKNWLTDG IQIKILFPFY LKPWHKSKFQ SFQKARLKKI KDKGEQNDFC FLTVWGMETE
     LPFGSAQKKP SFFEPISKQL TKRIKKFKTK SFLVLRIFKE RATIFLKVAK EIKNWFLKNF
     LFIKGKIKDL SKRNLISLFG PREIYELNET QKDSIMSNQM IHELSVQNKS MEWTNSSLSE
     NKIKNLINRI KTISNQIEEI SKEKQNLTNS CNKLRYDSKK MESSKKIWQT FKRKNTRLIR
     KSIFFVKFCI EQLSIAIFLG IINIPRITTQ LFFESTKTIL DKYIYKTEEN GEKINNKKTT
     IYFISTIKNL ISNSNKKKIS YNLCSLSQAY VFYKISQIKV SHVSKFSKLK AVLEYNRCIT
     SFFLKNQIKD FFQEQGIFHY KLKDKTLLNS EVNHWKNWLR SNYQYNLPQI AWARLGTQKW
     KKKINQDYLV LNPSLTNEDS YEKKKFDNYQ KKSFFEADSL LNPKHNLKKD SIYNLFCYKS
     INSTEKIFDM SIGIARDNCL VSCFLEKYNI RGIGEIRHRK YLDWRILNFW VTKKVNSEPW
     VDTKNKKKYI NTKVQNYQRI DKITKTGLAN KKRNFFDWMG MNEEILNHRR KNFEFFFFPE
     FFLFSSTYKM KPWVIPIKLL LLNFNENINV NKKITGKKKG FIPSNEKKSL RFFNLNKEEK
     ESAGQVELES DKEKKINPES ALSNHEKNIE ENYEESTIKK RKNKKQYKSN TEAELDLFLT
     RYSRFQLRWN SFFNQKILNN VKVYCLLVRL KNPNEIAISS IERGEMSLDI LMIEKNFTFA
     KLMKKGILII EPVRLSVQND GQRIIYRTIG ISLVHKNKHK INKRYKKKSY IEKKTIEKSI
     TKYQNKTVNR KKNHYDFFVP ENILSPKRRR EFRILICFNL KKKNARDRNS RFNKNIQNLT
     TVLDTKKDLA KDKNNLIKFK SFLWPNFRLE DLACMNRYWF NTTNGNHFSM IRIHMYTRFP
     IH