TI214_PELHO
ID TI214_PELHO Reviewed; 2552 AA.
AC Q06FP6;
DT 28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT 31-OCT-2006, sequence version 1.
DT 25-MAY-2022, entry version 37.
DE RecName: Full=Protein TIC 214 {ECO:0000250|UniProtKB:P56785};
DE AltName: Full=Translocon at the inner envelope membrane of chloroplasts 214 {ECO:0000250|UniProtKB:P56785};
DE Short=AtTIC214 {ECO:0000250|UniProtKB:P56785};
GN Name=TIC214 {ECO:0000250|UniProtKB:P56785}; Synonyms=ycf1-A;
GN and
GN Name=TIC214 {ECO:0000250|UniProtKB:P56785}; Synonyms=ycf1-B;
OS Pelargonium hortorum (Common geranium) (Pelargonium inquinans x Pelargonium
OS zonale).
OG Plastid; Chloroplast.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Geraniales; Geraniaceae; Pelargonium.
OX NCBI_TaxID=4031;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Ringo White;
RX PubMed=16916942; DOI=10.1093/molbev/msl089;
RA Chumley T.W., Palmer J.D., Mower J.P., Fourcade H.M., Calie P.J.,
RA Boore J.L., Jansen R.K.;
RT "The complete chloroplast genome sequence of Pelargonium x hortorum:
RT organization and evolution of the largest and most highly rearranged
RT chloroplast genome of land plants.";
RL Mol. Biol. Evol. 23:2175-2190(2006).
CC -!- FUNCTION: Involved in protein precursor import into chloroplasts. May
CC be part of an intermediate translocation complex acting as a protein-
CC conducting channel at the inner envelope.
CC {ECO:0000250|UniProtKB:P56785}.
CC -!- SUBUNIT: Part of the Tic complex. {ECO:0000250|UniProtKB:P56785}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast inner membrane
CC {ECO:0000250|UniProtKB:P56785}; Multi-pass membrane protein
CC {ECO:0000255}.
CC -!- SIMILARITY: Belongs to the TIC214 family. {ECO:0000305}.
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DR EMBL; DQ897681; ABI17313.1; -; Genomic_DNA.
DR EMBL; DQ897681; ABI17326.1; -; Genomic_DNA.
DR RefSeq; YP_784122.1; NC_008454.1.
DR RefSeq; YP_784135.1; NC_008454.1.
DR AlphaFoldDB; Q06FP6; -.
DR SMR; Q06FP6; -.
DR PRIDE; Q06FP6; -.
DR GeneID; 4362796; -.
DR GeneID; 4362888; -.
DR GO; GO:0009706; C:chloroplast inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR InterPro; IPR008896; TIC214.
DR PANTHER; PTHR33163; PTHR33163; 4.
DR Pfam; PF05758; Ycf1; 4.
PE 3: Inferred from homology;
KW Chloroplast; Coiled coil; Membrane; Plastid; Plastid inner membrane;
KW Protein transport; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..2552
FT /note="Protein TIC 214"
FT /id="PRO_0000262621"
FT TRANSMEM 15..35
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 54..74
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 78..98
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 119..136
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 154..174
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 243..263
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 362..382
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 423..443
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 452..472
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 304..325
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2045..2077
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 2416..2511
FT /evidence="ECO:0000255"
SQ SEQUENCE 2552 AA; 308172 MW; 1F0CD0B8988CE347 CRC64;
MNHITSKRLD IRATLIFGIF YGILITFSKL TSYLFLIRHW ISQDDEGTGK ARALSYGFTV
GHLLGYLLIY YLPFYKALSN FYLKIILALG LMLYQFFWTN HHLDIFLPKS FSTPQRDQTL
AFVYGLSYRL LNYTFFPNSI FSRMIVGYLV QCQFKILFLY TTFFVWMIGH LICIKWVQFL
TLWLQKNYSA FLILTHQLYL QDKIKKIRSR TIPIAKIFEY KPDPVMKPGI YRESQTIDEM
IQILATILFI VALYLLGKSP IPFVPHSPSA PNAVELARMS RLEEEAKVQR EIEDRFYPLE
DFDEEQKKDE KSADEEKKRA VEEENQEILD LEEEENQEIL DLEEEENQEI LDMDEEKGFE
NTLYTFFSDC FFESFSFYAF LFNRLKFYSG YLFNRLKFCY GYLFDLFSSS SRFLNRIEPL
FSPFLVVVKP FYLYFFNFFS VYIPHLKFLK WFLFNHNFVF SAIFRGFSHF FFNPRRWVIP
YRYIKTSFYE YSVKKGGFSQ FCFYKCQSDG KERTSFTYPL SLITFYKMIE GKLSLFRKKK
RLPDRDRLYT LWVLRNAKKK DSLNKELIKR VQKLKSGSPL RDVLDIRRKL FQFKYTPKVL
RSISETLFDQ MHPSGGKKRE NDPVWDGPSR GAFWYNHKLT KTAAEQRVDE EEHLQTMWLF
FKDLRPLNQK EQYLILERQK LERESQEKQK LRRQCFEKSL LGKTLRILQK MAPYFRAPQY
IPSNSMSRAF KLYRVSAYLT LDWQETTRIL RRVHKLRKRG MIIRVNEERE SWIRSHKERY
LKLKEIRKKR VQLEKEKRRP KKILLRLDKK TKKGTLKKKQ KEAFPLNTIL TRILVLNSHF
RTSSKRKRDS KDRRNLYSYP NPLLEKINKI RRNRNTVYHI MNTYYEGRSG FTHEDIPKMR
KKYQKYRQFQ LKLRTIMKEV PRWGYNIDDE KIDYSDYNIR NDDVVAEDVY LRTRKAKFRV
FRTKVWKYYE RHDKRELKQW YFYRYAKITH FRRNMVKGAD RTQRRKVTIC GWYEHRVQSP
LFLPKRRKTL ILIMLTLDVF ELMKKCYRFL RQDSRFQVRV KRISERINRI WKKLWNLPDS
QKSAIEAAIE AENELQGLRE SEEDKKKRQE RGDALEEWQE RREAHEIRAI CIAETWELLQ
SGHAVRSLIL LIQSFLRKNV IFPFLIIAKN MARILFFQSP ELFQDFADLK KETHTLCDFG
GIPLDESQDP IGWFTDGCQI RIHFPFEWKP WRETEQSKES SVAEDLYLTV FGRITNIPFG
TARKPYPFFK TVFEELKKKK ASQELKNLLT SGIRKLQKKG FLKFKKKGFL RKRLLAFQKK
SFQSKLLKGV KVKKRTNLKK GPQSKLTKKK KERKVDKTRA IINEIERVLK EKKKRLFIIQ
TSISSTKTSS HSKTSEALRR LSKILKRRKA RFIRKSTIFR KWIIEWIYVK ILFDLKNRFD
LKKRFLDEMN KKKSCLKMVA QFFFQFKKKR KNKKIDKAIK GINKKKRKKN RFISTIKKHS
FNMRNSQISK SQKTLVFDLS SLSQAYVFYK LSQTEKSSFR VSKFQNLRNC RVGMNRWKEW
LRGHFDYYLL SDIRWSRLEA QKWRNKMNQC RTAENHNFKK GDSYEIDSLP INPQKLKFKK
HLRYDLLAYS FLNAEYKKDP YVIAPSLVSN NQTAISHLYN IHKESLVNML TSNYKHLRDS
KEKHPLLDMH MDVNRTALRR RMNYNQILFH VEDKKKGSKV VDKVAIDSWV TGQNRVLPAG
SLTEDRVGFT EGAMVFLESV LKQLRERRRP YPESLDESFR PEWLKWPLEH LIGYIHKICD
MHLYFFSVYA LYWPEFYDRH RLAKLGCVFR YEKCYDKRRT PIWKKQKSMA KRKKDLAARK
KKMSGKAQSI KIAQREFDLS LILEPEEFEK IEKKNFFDWM GLNNENELEE LMERNNDEKK
SSFLESSFFL FPEFIQLYNL LNLYAKAEWT TPIHSFLQNG KIRSRSSYAD LKVEFDSFNW
YMYDKKEWPA KGRPLWDSNR ARRRRRHRRA LLNLGRKDPR KETTLDIMID PTERERAYAE
TISEMKAEEQ KKIDEEYEEK KEKRKKEQEE QGKAFDETSY RKNHKKRFAR VSTLKPIKYS
RFRKTALKDL KKSNYFRYQV HYSLRYLIAD FLTNVTRTSQ VTNKATNPKL LLVFIKDLIE
MSQFGIMGTT QNQLPTLEDI LNMGYLVLNP IRTFKRLRWE HVTYQILAIS LLHKNQFQKL
AYTPGPDNKR DPCLEIGVNK VKQTTYKVRK GRKVVESLSV RRLRVKRWWG LRVSYGKFGC
PRSFWTKLVR YLVHPFAIPL KAKARGKKKQ SPWSYERVFG LFHWKPEVHP KKKRKRTPWS
YERVFGQFHA DQMRFFYKIG VCGKFKRECT AILLSLITDP KRANDRIKKL ILLDEGVPDT
LVEKGLLVPE NLLSPRRRRQ LRIVNELNKK KKKEKRIPQH KLTPYNKLLK ETGRMDLNLL
LRELDEREKR QREERLNLVQ KKEREQEELR KKEEESKELN RIKKKLMRLR FFLWPNYRLE
DLACMNRYWF DTTNGSRFSM LRIRVYPRLK TR
