TI214_PLAOC
ID TI214_PLAOC Reviewed; 1915 AA.
AC Q09FY8;
DT 28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT 17-OCT-2006, sequence version 1.
DT 25-MAY-2022, entry version 38.
DE RecName: Full=Protein TIC 214 {ECO:0000250|UniProtKB:P56785};
DE AltName: Full=Translocon at the inner envelope membrane of chloroplasts 214 {ECO:0000250|UniProtKB:P56785};
DE Short=AtTIC214 {ECO:0000250|UniProtKB:P56785};
GN Name=TIC214 {ECO:0000250|UniProtKB:P56785}; Synonyms=ycf1;
OS Platanus occidentalis (Sycamore) (American plane tree).
OG Plastid; Chloroplast.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Proteales; Platanaceae; Platanus.
OX NCBI_TaxID=4403;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16934154; DOI=10.1186/1471-2229-6-17;
RA Moore M.J., Dhingra A., Soltis P.S., Shaw R., Farmerie W.G., Folta K.M.,
RA Soltis D.E.;
RT "Rapid and accurate pyrosequencing of angiosperm plastid genomes.";
RL BMC Plant Biol. 6:17-17(2006).
CC -!- FUNCTION: Involved in protein precursor import into chloroplasts. May
CC be part of an intermediate translocation complex acting as a protein-
CC conducting channel at the inner envelope.
CC {ECO:0000250|UniProtKB:P56785}.
CC -!- SUBUNIT: Part of the Tic complex. {ECO:0000250|UniProtKB:P56785}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast inner membrane
CC {ECO:0000250|UniProtKB:P56785}; Multi-pass membrane protein
CC {ECO:0000255}.
CC -!- SIMILARITY: Belongs to the TIC214 family. {ECO:0000305}.
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DR EMBL; DQ923116; ABI49837.1; -; Genomic_DNA.
DR RefSeq; YP_740623.1; NC_008335.1.
DR AlphaFoldDB; Q09FY8; -.
DR PRIDE; Q09FY8; -.
DR GeneID; 4271362; -.
DR GO; GO:0009706; C:chloroplast inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR InterPro; IPR008896; TIC214.
DR PANTHER; PTHR33163; PTHR33163; 1.
DR Pfam; PF05758; Ycf1; 1.
PE 3: Inferred from homology;
KW Chloroplast; Membrane; Plastid; Plastid inner membrane; Protein transport;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..1915
FT /note="Protein TIC 214"
FT /id="PRO_0000262625"
FT TRANSMEM 18..38
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 64..84
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 90..110
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 126..146
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 174..194
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 230..250
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 260..319
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1566..1631
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 277..319
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1585..1601
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1602..1631
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1915 AA; 227739 MW; FE63C74A3FD8C7C2 CRC64;
MILKSFLLGN LLSLCMKIIN SVVVVGLYYG FLTTFSIGPS YLFLLRARVM EEGTEKEVSA
TTGFITGQLM MFISIYYAPL HLALGRPHTI TVLVLPYLLF HFFWHNHKYF LNINYGSTIR
NSIRNLNIQC VFLNNLIFPL FNHFILPSST LARLINIYMF QCNNKMLFVT SSFVGWLIGH
ILFMKWVELV LIWIRQNHFF RSNALFIRSN VLIVPKKNLV PELRNSMARI FSILLFITCI
YYLGRMPSTL VTKKMKETSK MKQMGQSEEE TDVEIETTSE TKETKEEQEG STEEDPSPSL
YSEEKEDPDK IDETEEIRVN GNEKSKDEFH FRFKKTCYKY KNSPVFQNFY LDGNQENSKL
EILKYEKKNL FWFQKPLVTL LFDYKRWNRP LRYIKNNQLE NAVRNEMSQY FFYTCQSDGK
QRISFTYPPS LSTFWEMIQR KMSLYTTEKL SPEELYNHWV YTNEQKRNNV SKEFINRIEA
LDKGSLTLDV LEKRTRLCND KTEQQCLPKV YDPFLNGPYR GTIKKVSSSS IMNDYLITSI
ENSIEKLWIN KIHGILPTDY REFEQKEKID TFDGKSLSTD IFHFLTPISK FAGESTTSLN
WKGLPLLAEQ ERNYSKDQAK YLKFLFAAVT TDPNNQIIRN KSIVINEICK KVPRWSYKLI
DDLEQQEGEY EEESAEDHQI RSRKAKRVVI FTDNEPDTNT HTNTNNTSDR DEVEEVALIR
YSQQPDFRRD IIKGSMRAQR RKIVIWELFQ ANVHSPLFLD KIDKTFFFSF DISEMTKFIF
RNCMGKNTKL KTSDPEEKEK KEKKEENERI AVAETWDSIL FAQPIRGSML VTQSILRKYI
VLPLLIIAKN TARILLFQFP EWFEDWEEWN REIHVKCTYN GVPLSETEFP RNWLKDGIQI
KILFPLCLKP WHRFKLRSHH RGPMKKKGKK YNFCFLTVWG METELPFGSP RNQPSFFEPI
LKELEKKIRK VKNQFFRILR VVKERTKWFL TVLKEKKRWV IEIILFIKRI MKELAKINPI
LLFGLKEVYE SSENKNRKNS QNSITIISNQ IIHESPIRIR STDWTNYYYS LTEKKMKNLA
DRTSTIRNQI ERITKDKKKI FLTPEINISP KKMSCGDKRS ESLKSFWEIV KKRSIRLIRK
WHFFLKFVIE KIYLLCIINI PRINAQLFLE STKKILDKYI YNYNDETNQE EIDEINQKKI
HFISTIKKSL FHISNNNSQI FCDLSSLSQA YVFYKLSQTK VINKYHLRSV LEYHERSLFL
KDRIKDYFRT QGIFHFESRH KKLRNSGMND WKNWLKGHYQ YQYDLSQTRW ARLVPQKWQN
RVNQRRTTQN KDSKKLGSYE KDQLIHYQKQ NDYAVELLSN KKEKLKKHYG YDLLSHKYIN
YENKKDLYIY RSPLQVNEGR EITYNYTTHK LESFCVLGGI PIRDYLGEDY IIETDKNPDR
KYFDWGILHF CLRKEVDIDT WTNMDTEASI NKKTKTGTNY SQIVEKINKK DLFMIHEEIN
PSNQKKKPFD WMGMNEEILN RTISNLELWF VPEFLLLYDT YKMKPWGIPI KLLLVNLNGN
ENVSENKNIN RKQKKNLPLS SNKNKKKSLE LENRNQEEKE SSSQGDLGSN AQNQGNLGPN
AQNQGNLGSV LPNQQKNLEE DYAGSDIKKV RKKKQFKSKA EVELDLLLKK YLLFQLRWNG
SLNQRILNNI KIYCFLLRLI NPKEITISSI QKGEMSLGIM LIKRDLTFTE LIKRGIFIIE
PVRLSIKWDG QFIMYQTIGI SLVHKSKHQT NQRYREKRCI DKNHFEGFIA RHENMLGNGD
ENHYDLLVPE NISSPRRRRE LRILTCFHFL NGNVLDRNPV FCNGNNVKNC GQFLNEDKHL
DRDTNKLINM KLKFFLWPNY RLEDLACMNR YWFDTNNGSR FSMSRIHMYP RLKIS
