ID   TI214_POPAL             Reviewed;        1820 AA.
AC   Q14FA0;
DT   28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT   22-AUG-2006, sequence version 1.
DT   25-MAY-2022, entry version 36.
DE   RecName: Full=Protein TIC 214 {ECO:0000250|UniProtKB:P56785};
DE   AltName: Full=Translocon at the inner envelope membrane of chloroplasts 214 {ECO:0000250|UniProtKB:P56785};
DE            Short=AtTIC214 {ECO:0000250|UniProtKB:P56785};
GN   Name=TIC214 {ECO:0000250|UniProtKB:P56785}; Synonyms=ycf1;
OS   Populus alba (White poplar).
OG   Plastid; Chloroplast.
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Malpighiales; Salicaceae; Saliceae; Populus.
OX   NCBI_TaxID=43335;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Okumura S., Yamashita A., Kanamoto H., Hattori M., Takase H., Tomizawa K.;
RT   "Complete structure of the chloroplast genome of Populus alba.";
RL   Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in protein precursor import into chloroplasts. May
CC       be part of an intermediate translocation complex acting as a protein-
CC       conducting channel at the inner envelope.
CC       {ECO:0000250|UniProtKB:P56785}.
CC   -!- SUBUNIT: Part of the Tic complex. {ECO:0000250|UniProtKB:P56785}.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast inner membrane
CC       {ECO:0000250|UniProtKB:P56785}; Multi-pass membrane protein
CC       {ECO:0000255}.
CC   -!- SIMILARITY: Belongs to the TIC214 family. {ECO:0000305}.
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DR   EMBL; AP008956; BAE97262.1; -; Genomic_DNA.
DR   RefSeq; YP_665614.1; NC_008235.1.
DR   AlphaFoldDB; Q14FA0; -.
DR   PRIDE; Q14FA0; -.
DR   GeneID; 4178199; -.
DR   KEGG; palz:4178199; -.
DR   GO; GO:0009706; C:chloroplast inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR008896; TIC214.
DR   PANTHER; PTHR33163; PTHR33163; 2.
DR   Pfam; PF05758; Ycf1; 2.
PE   3: Inferred from homology;
KW   Chloroplast; Membrane; Plastid; Plastid inner membrane; Protein transport;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..1820
FT                   /note="Protein TIC 214"
FT                   /id="PRO_0000262626"
FT   TRANSMEM        18..38
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        67..87
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        90..110
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        127..147
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        175..195
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        224..244
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        1103..1123
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          250..310
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          744..763
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        267..310
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1820 AA;  218104 MW;  233DE6D9273701DE CRC64;
     MILKSFILGN LVSLCMKIIN SVVVVGLYYG FLTTFSMGPS YLFLLRARVI EEGEEGTEKK
     VSATTGFITG QLMMFISIYY APLHLALGRP HTITVLALPY LLFHFFWNNH KHFFDYGSTT
     RNSMRNLSIQ CVFLNNLIFQ LFNHFILPSS MLVRLVNIYM FRCNNKMLFV TSSFVGWLIG
     HILFMKWVGL ILVWIQQNNS LRSNKYIRSN KYLVSELRNS MARIFSILLF ITCVYSLGRI
     PSPIFTKKLK ETSETEEREE ETDVEIETTP ETKGTKQEQE GSTEEDPSSS LFSEEKENPD
     KIDETEEIRV NGKEKTKDEF HFHFKETCYK NRPVYETFYL DGNQENSKLE IFLDKKDKDL
     VWFEKPRVTI LFDYKRWNRP FRYIKNDQFK NAVRKEMSQY FFSTCRSDGK ERISFTYPPS
     LSTFLEMIQR KMSLFTTEKL SSDELYNHWN YNNEQKKKNL SNEFINRVEV LDKGFRVLNI
     LEKKTRLCND ETKKEYLPKI YDPFLSGLYR GKVNFFFSPS IINEISIKNY IEMLWINKIY
     LILLISNYQE FEPKMEDRIR ILKFLFDAII VDSKNKKIVK KSTEIKKEIS KQIPRWSYKL
     IDDLEQQEGE NEENAAEDHE IRSRKAKRVV IFTDNQENPD SNTYNNSKTK DTTNFDQTGE
     VALIRYSQQS DFRRDIIKGS MRTQRRKIAI LKLFQANLHS PLFLDRIDKF LFFAFDTSEL
     MKIMFINWMC KNAEFTISDS TYTEEKTKES DKKEKEEIKN RREEDKREEK VRIEIAETWD
     SIIFAQAIRG CVLVIQSILR KYILLPSLII AKNMIRMLLF QIPEWSEDLK DWNREMHVKC
     TYNGVQLSET EFPKNWLTDG IQIKILFPFR LQPWHRSKFK FLSKDPIKKK RQKNDFCFLT
     VWGMEAELPF GSPRKELSLF EPIFKKLKKK IRKLKKNGFL TLTILKEKRK LFLHLPKETK
     NWFIKGILFL KEIINKFSKS KRNPILLFGF REVYELNETK NEKNSPINNR TIHKFSTSIR
     SMDWINYSLT EKKMKDLNAR TKTIRNQIEK ITKEKKKRFL ISERNISPNK LSYNAKRLKF
     KSSKNILQIL KRNNAQLVRK SYFFIKILIE KIYIDILLAI INIPRINVQF FLESPRKMIN
     KYIYMYNKKE NNKRIDKTNQ NTPIHFISII KKALNYSNFN KNSKIFYNIT SLSQAYVFYK
     LSQVQVINLY KLRSVLQYHG ASLFLKNEIK DYFGVQGRFQ FKLKDTNFRN SVMNEWKNWV
     RSNYQYKYDL SQIRWSSLIS QKWRNRMNQQ HMIQNKDLNK WNLYDKDQLI HYEKQNNFEV
     DSLSNQKDNF KKYYRYNILL YKSINYEDKK DSSIYELPFQ LNNKQELFYN YKIDKRKLFD
     MSGGIPVNKH LTEDDIIDTE KSSHRKYLDW RILHFGLRKK VDIESWIDTG TKQKKNLFDW
     MGMNEEILDR PTSNLEFWFF PKFVILCNAY KIKSWVIPIK LLFLNFNGTK NVSENKKINK
     KKNNDPFISI SSNETKSIQL KNQNHEEKES EDQVDLESVL VNQEKDVEED YVRSDRKERR
     KKKQYKSNTE AELDFLLKRY LCFQLRWDDS LNEKIINNIK IYCLLLRLTN PREIIISSIQ
     RGELSLDILM IQKDLTLTEL MKKGILIIES TRLSVKNDGK FIMYQTINIL LVHKRKQQIN
     QRYRKKNYID KKNFTESIVI NQSLTRNKDK NNYDLLVPEN LLSSKHRREL RILISFNSKN
     GNDINTEIIN NNNIKNHAHI IDKSKRFDRD KNKLIKLKLF LWPNYRLEDL ACINRYWFDT
     NNASRFSMIR IHICPRLKIR