TI214_POPTR
ID TI214_POPTR Reviewed; 1822 AA.
AC A4GYX4; A4GYW3;
DT 08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 17-APR-2007, sequence version 1.
DT 25-MAY-2022, entry version 47.
DE RecName: Full=Protein TIC 214 {ECO:0000250|UniProtKB:P56785};
DE AltName: Full=Translocon at the inner envelope membrane of chloroplasts 214 {ECO:0000250|UniProtKB:P56785};
DE Short=AtTIC214 {ECO:0000250|UniProtKB:P56785};
GN Name=TIC214 {ECO:0000250|UniProtKB:P56785}; Synonyms=ycf1-A;
GN OrderedLocusNames=Poptr_cp087;
GN and
GN Name=TIC214 {ECO:0000250|UniProtKB:P56785}; Synonyms=ycf1-B;
GN OrderedLocusNames=Poptr_cp076;
OS Populus trichocarpa (Western balsam poplar) (Populus balsamifera subsp.
OS trichocarpa).
OG Plastid; Chloroplast.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Malpighiales; Salicaceae; Saliceae; Populus.
OX NCBI_TaxID=3694;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nisqually;
RX PubMed=16973872; DOI=10.1126/science.1128691;
RA Tuskan G.A., Difazio S., Jansson S., Bohlmann J., Grigoriev I.,
RA Hellsten U., Putnam N., Ralph S., Rombauts S., Salamov A., Schein J.,
RA Sterck L., Aerts A., Bhalerao R.R., Bhalerao R.P., Blaudez D., Boerjan W.,
RA Brun A., Brunner A., Busov V., Campbell M., Carlson J., Chalot M.,
RA Chapman J., Chen G.-L., Cooper D., Coutinho P.M., Couturier J., Covert S.,
RA Cronk Q., Cunningham R., Davis J., Degroeve S., Dejardin A.,
RA dePamphilis C.W., Detter J., Dirks B., Dubchak I., Duplessis S.,
RA Ehlting J., Ellis B., Gendler K., Goodstein D., Gribskov M., Grimwood J.,
RA Groover A., Gunter L., Hamberger B., Heinze B., Helariutta Y.,
RA Henrissat B., Holligan D., Holt R., Huang W., Islam-Faridi N., Jones S.,
RA Jones-Rhoades M., Jorgensen R., Joshi C., Kangasjaervi J., Karlsson J.,
RA Kelleher C., Kirkpatrick R., Kirst M., Kohler A., Kalluri U., Larimer F.,
RA Leebens-Mack J., Leple J.-C., Locascio P., Lou Y., Lucas S., Martin F.,
RA Montanini B., Napoli C., Nelson D.R., Nelson C., Nieminen K., Nilsson O.,
RA Pereda V., Peter G., Philippe R., Pilate G., Poliakov A., Razumovskaya J.,
RA Richardson P., Rinaldi C., Ritland K., Rouze P., Ryaboy D., Schmutz J.,
RA Schrader J., Segerman B., Shin H., Siddiqui A., Sterky F., Terry A.,
RA Tsai C.-J., Uberbacher E., Unneberg P., Vahala J., Wall K., Wessler S.,
RA Yang G., Yin T., Douglas C., Marra M., Sandberg G., Van de Peer Y.,
RA Rokhsar D.S.;
RT "The genome of black cottonwood, Populus trichocarpa (Torr. & Gray).";
RL Science 313:1596-1604(2006).
CC -!- FUNCTION: Involved in protein precursor import into chloroplasts. May
CC be part of an intermediate translocation complex acting as a protein-
CC conducting channel at the inner envelope.
CC {ECO:0000250|UniProtKB:P56785}.
CC -!- SUBUNIT: Part of the Tic complex. {ECO:0000250|UniProtKB:P56785}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast inner membrane
CC {ECO:0000250|UniProtKB:P56785}; Multi-pass membrane protein
CC {ECO:0000255}.
CC -!- MISCELLANEOUS: There is a partial copy of the N-terminus (positions 1-
CC 601) of ycf1 in the inverted repeat (ABO36758).
CC -!- SIMILARITY: Belongs to the TIC214 family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; EF489041; ABO36769.1; -; Genomic_DNA.
DR EMBL; EF489041; ABO36758.1; -; Genomic_DNA.
DR RefSeq; YP_001109554.1; NC_009143.1.
DR RefSeq; YP_001109565.1; NC_009143.1.
DR AlphaFoldDB; A4GYX4; -.
DR EnsemblPlants; PNT14862; PNT14862; POPTR_010G052900v3.
DR GeneID; 4929736; -.
DR GeneID; 4929748; -.
DR Gramene; PNT14862; PNT14862; POPTR_010G052900v3.
DR KEGG; pop:4929736; -.
DR KEGG; pop:4929748; -.
DR eggNOG; ENOG502QSDY; Eukaryota.
DR InParanoid; A4GYX4; -.
DR Proteomes; UP000006729; Chloroplast.
DR ExpressionAtlas; A4GYX4; baseline and differential.
DR GO; GO:0009706; C:chloroplast inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR InterPro; IPR008896; TIC214.
DR PANTHER; PTHR33163; PTHR33163; 2.
DR Pfam; PF05758; Ycf1; 2.
PE 3: Inferred from homology;
KW Chloroplast; Coiled coil; Membrane; Plastid; Plastid inner membrane;
KW Protein transport; Reference proteome; Transmembrane; Transmembrane helix;
KW Transport.
FT CHAIN 1..1822
FT /note="Protein TIC 214"
FT /id="PRO_0000326585"
FT TRANSMEM 18..38
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 67..87
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 90..110
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 127..147
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 175..195
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 224..244
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 250..310
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 742..765
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1031..1102
FT /evidence="ECO:0000255"
FT COMPBIAS 267..310
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 744..765
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 570..603
FT /note="IVDSKNKKIVKKSTEIKKEISKQIPRWSYKLIDD -> ATKMGYFLNLINEF
FT VTKSSFNLKRLFPIVIEK (in Ref. 1; ABO36758)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 1822 AA; 218334 MW; F1B8838DBDDF2B89 CRC64;
MILKSFILGN LVSLCMKIIN SVVVVGLYYG FLTTFSMGPS YLFLLRARVI EEGEEGTEKK
VSATTGFITG QLMMFISIYY APLHLALGRP HTITVLALPY LLFHFFWNNH KHFFDYGSTT
RNSMRNLSIQ CVFLNNLIFQ LFNHFILPSS MLVRLVNIYM FRCNNKMLFV TSSFVGWLIG
HILFMKWVGL ILVWIQQNNS LRSNKYIRSN KYLVSELRNS MARIFSILLF ITCVYSLGRI
PSPIFTKKLK ETSETEEREE ETDVEIETTP ETKGTKQEQE GSTEEDPSSS LFSEEKENPD
KIDETEEIRV NGKEKTKDEF HFHFKETCYK NRPVYETFYL DGNQENSKLE IFLDKKDKDL
VWFEKPRVTI LFDYKRWNRP FRYIKNDQFK NAVRKEMSQY FFSTCRSDGK ERISFTYPPS
LSTFLEMIQR KMSLFTTEKL SSDELYNHWN YNNEQKKKNL SNEFINRVEV LDKGFRVLNI
LEKKTRLCND ETKKEYLPKI YDPFLSGLYR GKVNFFFSPS IINEISIKNY IEMLWINKIY
LILLISNYQE FEPKMEDRIR ILKFLFDAII VDSKNKKIVK KSTEIKKEIS KQIPRWSYKL
IDDLEQQEGE NEENAAEDHE IRSRKAKRVV IFTDNQENPD SNTYNNSKTK DTTNFDQTGE
VALIRYSQQS DFRRDIIKGS MRTQRRKIAI LKLFQANLHS PLFLDRIDKF LFFAFDTSEL
MKIMFINWMC KNAEFTISDS TSTYTEEKTK ESDKKEKEEI KNRREEDKRE EKVRIEIAET
WDSIIFAQAI RGCVLVIQSI LRKYILLPSL IIAKNIIRML LFQIPEWSED LKDWNREMHV
KCTYNGVQLS ETEFPKNWLT DGIQIKILFP FRLQPWHRSK FKFLSKDPIK KKRQKNDFCF
LTVWGMEAEL PFGSPRKELS LFEPIFKKLK KKIRKLKKNG FLTLTILKEK RKLFLHLPKE
TKNWFIKGIL FLKEIINKFS KSKRNPILLF GFREVYELNE TKNEKNSPIN NRTIHKFSTS
IRSMDWINYS LTEKKMKDLN ARTKTIRNQI EKITKEKKKR FLISERNISP NKLSYNAKRL
KLKSSKNILQ ILKRNNAQLV RKSYFFIKIL IEKIYIDILL AIINIPRINV QFFLESPRKM
INKYIYMYNK KENHKRIEKT NQNTLIHFIS IIKKALNYSN FNKNSKIFYN ITSLSQAYVF
YKLSQVQVIN LYKLRSVFQY HGASLFLKNE IKDYFGVQGR FQFKLKDTNF RNSVMNEWKN
WVRSTYQYKY DLSQIRWSSL ISQKWRNRMN QQHMIQNKDL NKWNLYDKDQ LIHYEKQNNF
EVDSLSNQKD NFKKYYRYNI LLYKSINYED KKDSSIYELP FQLNNKQELF YNYKIDKRKL
FDMSGGIPVN KHLTEDDIID TEKSSHRKYL DWRILHFGLR KKVDIESWID TGTKQKKNLF
DWMGMNEEIL DRPTSNLEFW FFPKFVILCN AYKIKSWVIP IKLLFLNFNG TKNVSENKKI
NKKKNNDPFI SISSNETKSI QLKNQNHEEK ESEDQVDLES VLVNQEKDVE EDYVRSDRKE
RRKKKQYKSN TEAELDFLLK RYLCFQLRWD DSLNQKIINN IKIYCLLLRL TNPREIIISS
IQRGELSLDI LMIQKDLTLT ELMKKGILII ESTRLSVKND GKFIMYQTIN ILLVHKRKQQ
INQRYRKKNY IDKKNFNESI VINQSLTRNK DKNNYDLPVP ENLLSSKHRR ELRILISFNS
KNGNDINTEI INNNNIKNHA HIIDKRKHFD RDKNKLIKLK LFLWPNYRLE DLACINRYWF
DTNNASRFSM IRIHICPRLK SR
