ID   TI214_PSINU             Reviewed;        1703 AA.
AC   Q8WHX1;
DT   28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   25-MAY-2022, entry version 46.
DE   RecName: Full=Protein TIC 214 {ECO:0000250|UniProtKB:P56785};
DE   AltName: Full=Translocon at the inner envelope membrane of chloroplasts 214 {ECO:0000250|UniProtKB:P56785};
DE            Short=AtTIC214 {ECO:0000250|UniProtKB:P56785};
GN   Name=TIC214 {ECO:0000250|UniProtKB:P56785}; Synonyms=ycf1;
OS   Psilotum nudum (Whisk fern) (Lycopodium nudum).
OG   Plastid; Chloroplast.
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Polypodiopsida; Ophioglossidae; Psilotales; Psilotaceae; Psilotum.
OX   NCBI_TaxID=3240;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Kingyoku;
RX   PubMed=15240838; DOI=10.1093/molbev/msh203;
RA   Nishiyama T., Wolf P.G., Kugita M., Sinclair R.B., Sugita M., Sugiura C.,
RA   Wakasugi T., Yamada K., Yoshinaga K., Yamaguchi K., Ueda K., Hasebe M.;
RT   "Chloroplast phylogeny indicates that bryophytes are monophyletic.";
RL   Mol. Biol. Evol. 21:1813-1819(2004).
CC   -!- FUNCTION: Involved in protein precursor import into chloroplasts. May
CC       be part of an intermediate translocation complex acting as a protein-
CC       conducting channel at the inner envelope.
CC       {ECO:0000250|UniProtKB:P56785}.
CC   -!- SUBUNIT: Part of the Tic complex. {ECO:0000250|UniProtKB:P56785}.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast inner membrane
CC       {ECO:0000250|UniProtKB:P56785}; Multi-pass membrane protein
CC       {ECO:0000255}.
CC   -!- SIMILARITY: Belongs to the TIC214 family. {ECO:0000305}.
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DR   EMBL; AP004638; BAB84282.1; -; Genomic_DNA.
DR   RefSeq; NP_569693.1; NC_003386.1.
DR   AlphaFoldDB; Q8WHX1; -.
DR   PRIDE; Q8WHX1; -.
DR   GeneID; 2545230; -.
DR   GO; GO:0009706; C:chloroplast inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR008896; TIC214.
DR   PANTHER; PTHR33163; PTHR33163; 2.
DR   Pfam; PF05758; Ycf1; 3.
PE   3: Inferred from homology;
KW   Chloroplast; Coiled coil; Membrane; Plastid; Plastid inner membrane;
KW   Protein transport; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..1703
FT                   /note="Protein TIC 214"
FT                   /id="PRO_0000262627"
FT   TRANSMEM        39..61
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        67..87
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        90..110
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        138..158
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        174..194
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        220..240
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          615..643
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1431..1494
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          618..660
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        1451..1475
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1703 AA;  203254 MW;  3D99D0F7555FC1F7 CRC64;
     MIGRLYMKKL KNLFLFLSSL CPVFPWISQI SLVMPFGLYY GFLTALPIGP SQILSIRTFF
     LEGNRSGIIC ILGSMMGQFV ILLSIYCSPL YVMLVKPHLM TLLVIPYMFY YWYRTKNPSR
     YYILHPIKSL THAHTRNLLL DSFIFQLLNP ILLPNPVLTR LLNLFLFRYS SNVFFLTSSL
     LGWLCGHILF INSIKLLLFR IEHDSPIIYI LMKRSISRTF SILISITFFL YLGRSPVPLI
     TKKFADEITL SDQKIKENLW EESLWLYRPW PTSFFDQYRW NRPIRYIPNS KSSHNGFVKK
     QVSKFFYDEC ITDGKNAISF ASQPSLSIFK KQLMNYLHNS DISISTKDSY KGWIETKREK
     RDALNNEFKD RIQFVYNSST IEEAMENKTG FSHDRNHFLV KVNDPFLSGS SRIRIPNKKY
     SSSLLKLHDS KDQTMKISKK TKRKHTRNKM RNWIFNKHKK WQHNKFPLPW EPIPTKAEKV
     FWRILNESEN PIILEMLTTL NSIKEKNYQF RITWEHIFQL PRIEKAIFLF RSKQEIEDSI
     FRYPSHLSLK NLTLFNIFTR SKNIFYSAKI AVSPILQIEE MQKELPRYNS RLRSDRIDAV
     NVDVDIRQRK IKNLGPRKGK LEDKEKEKEK AAQTQTEVKK EREKEKEERV IKRFQNQSDF
     RRKLVKGSIR ARRRKTGIWR LYQSGTHSPF FLRMKEIPIS FQSSINALRL NKMKDERAIL
     GIGKELRPFN LYKKRSKADR LTIAARFDFP IAHAGRGVLL IIQSNIRKYV ILPILIICKN
     IGRIMLFQSP EWKEDWAEWN QEIHIKCTYD GIEVSHRHLP AHWFKEGLQI KILYPFHLKP
     WHIHRTNNIN DLRNEAQIQK EISDFGKQRK LSFSYLTIWG YQTSSVFGSM KKRPSFWRPI
     ANALKKKLQR NLFSKLTWIS HFFYEIILLS RTFIISKKPN NIPEMSIQSN ELRYDVSDYE
     LIQKYPNSNE KNDYVVMNEI SIESNNRNGK EISHESQDQY KDNFNNIRSF NDIETLLTDI
     SGTSVEESYR DRIETYLRLN KKNHRYAINI RLIWNKQLVQ TQQEFSRFRR IIMQFMHKGY
     RLAKRFLTKF YREIFRRFTF SIQLSIQLVL RLTKNITKLS EKNKVYQNLN LLKKNEQNLK
     IDSSRNKPVL SQAYVFQKLW HARTRTKIDV HYLVQSLERE IVNSIENNEL KASKLKDLKW
     NEHNYLNDHI KDLLEIQGLL KETQTFTEKN WKEWLHCFTR YQISSKIEYG IVPQKWKNEV
     KKRWKSNTNK LDKNKEYKTL EKENKYSLYE TNNMLKQRIN NRNNYCEFYN LLYSFIDSTK
     ASNIIKLPIQ QKGKEDPIQY INDINKIHEN IHLNSKKKYK RPQFQSISTE KGDIDSNLML
     WLLPNLLDTK PESVTNSLDS YSFEMYLSQN EDKDSLKKEI RFNAKKLNLD TKEPTSDAMK
     PTSDTKELIS DTNEPTSDIK SDDQSENQNK PLKEKSIRER KHHRPIPQVK WKSKSVEKKM
     QRINNLTSFL SVIEDRKNME NYIISFCMKM GIDIDLLNSF FTNTEDELSI QLLDDSAHRL
     PRLLNDQTLV RKMVSILLNF EKQFEEGITS KISSQSISSI YRTEKKYSVN SYNLEDIMLS
     RRYRELRILN SLILEKQYVN FDHWIDKSEK YPFLNLPSQV QIIKRFLWPT YRLEDLACMN
     RFWFNTNNGS RFAMLKLRMY CPD