ID   TI214_SOLBU             Reviewed;        1887 AA.
AC   Q2MIC9;
DT   28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT   07-FEB-2006, sequence version 1.
DT   03-AUG-2022, entry version 37.
DE   RecName: Full=Protein TIC 214 {ECO:0000250|UniProtKB:P56785};
DE   AltName: Full=Translocon at the inner envelope membrane of chloroplasts 214 {ECO:0000250|UniProtKB:P56785};
DE            Short=AtTIC214 {ECO:0000250|UniProtKB:P56785};
GN   Name=TIC214 {ECO:0000250|UniProtKB:P56785}; Synonyms=ycf1;
OS   Solanum bulbocastanum (Wild potato).
OG   Plastid; Chloroplast.
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum.
OX   NCBI_TaxID=147425;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. PT29;
RX   PubMed=16575560; DOI=10.1007/s00122-006-0254-x;
RA   Daniell H., Lee S.-B., Grevich J., Saski C., Quesada-Vargas T., Guda C.,
RA   Tomkins J., Jansen R.K.;
RT   "Complete chloroplast genome sequences of Solanum bulbocastanum, Solanum
RT   lycopersicum and comparative analyses with other Solanaceae genomes.";
RL   Theor. Appl. Genet. 112:1503-1518(2006).
CC   -!- FUNCTION: Involved in protein precursor import into chloroplasts. May
CC       be part of an intermediate translocation complex acting as a protein-
CC       conducting channel at the inner envelope.
CC       {ECO:0000250|UniProtKB:P56785}.
CC   -!- SUBUNIT: Part of the Tic complex. {ECO:0000250|UniProtKB:P56785}.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast inner membrane
CC       {ECO:0000250|UniProtKB:P56785}; Multi-pass membrane protein
CC       {ECO:0000255}.
CC   -!- SIMILARITY: Belongs to the TIC214 family. {ECO:0000305}.
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DR   EMBL; DQ347958; ABC56272.1; -; Genomic_DNA.
DR   RefSeq; YP_538908.1; NC_007943.1.
DR   AlphaFoldDB; Q2MIC9; -.
DR   PRIDE; Q2MIC9; -.
DR   GeneID; 3989472; -.
DR   GO; GO:0009706; C:chloroplast inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR008896; TIC214.
DR   PANTHER; PTHR33163; PTHR33163; 1.
DR   Pfam; PF05758; Ycf1; 1.
PE   3: Inferred from homology;
KW   Chloroplast; Coiled coil; Membrane; Plastid; Plastid inner membrane;
KW   Protein transport; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..1887
FT                   /note="Protein TIC 214"
FT                   /id="PRO_0000262629"
FT   TRANSMEM        18..38
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        64..84
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        87..107
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        124..144
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        172..192
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        221..241
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          248..300
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          786..805
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1569..1603
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          775..816
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        266..283
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1576..1596
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1887 AA;  225063 MW;  5A9B668A3F13E476 CRC64;
     MIFQSFLLGN LVSLCMKIIN SVVVVGLYYG FLTTFSIGPS YLFLLRALVM EEGTEKKVSA
     TTGFITGQLM MFISIYYAPL HLALGRPHTI TVLALPYLLF HFFWNNHKHF FDYGSTTRNS
     MRNLSIQCVF LNNLIFQLFN HFILPSSMLA RLVNIYLFRC NNKILFVTSG FVGWLIGHIL
     FMKWLGLVLV WIRQNHSIRS NKYIRSNKYL VLELRNSMAR IFSILLFITC VYYLGRIPSP
     ILTKKLKEAS KTEERVESEE ERDVEIETAS EMKGTKQEQE GSTEEDPYPS PSLFSEEGWD
     PDKIDETEEI RVNGKDKIKD KFHSHLTETG YNNINTSNSP IYDYQDSYLN NNNTGNLENF
     KLQLLDKKNE NQDLFWFQKP LVSLLFDYNR WNRPFRYIKN NRFEQAVRTE MSQYFFDTCK
     SDGKQRISFT YPPSLSTFWK MIKRKIPLLS LQKTLPNKLD TQWVSTNKEK SNNLNKEFLN
     RLEILDKESL SMDILETRTR LCNDDTKKEY VPKMYDPLLN GPYRGTIKKG VSSSIINNTL
     LENWEKRVRL NRIHTIFLPN IDYQEFEQKA YTIDKKPLST EIDEFLTLIN ELGNEPKSSL
     NVKGLSLFSD QEQRRAKSEN RTKFVKFVFN AIDPNEPKSG KKSIGIKEIS KKVPRWSHKL
     ITELDQQMGE FQDRASIDHQ LRSRKAKRVV IFTDNNATND PEEEVALISY SQQSDFRRGI
     IKGSMRAQRR KTFISKLFQA NVHSPLFVDR ITPLRLFSFD ISELIKPIFR NWTGKEREFK
     ILESREEQTK REEKKEKDKK EDNKRKEQAR IAIEEAWDNI PFAQIIRGYM LITQSILRKY
     ILLPSLIIAK NLGRMLFLQL PEWSEDLQEW NREMQIKCTY NGVQLSETEF PKDWLRDGIQ
     IKILFPFCLK PWHISKLYPS RGELMKKKKQ KDDFCFLTVW GMEAELPFGS PRKRPSFFEP
     IFKELEKKIG KFKKKYFLTL KILKGKTKLF RSVSKETKKW FIQSIGFLKK IKKELSKVNP
     IVLFRFKEIS ESNETKKEKD YLISNQIINE SFSQIESGNW PNSSLIEKKM KDLTDRTSTI
     KNQIERITKE KKKVTPEIDI NPNKTNNIKK LESPKKFFQI LKSRNTRVIW KFHYFLKLFI
     QRLYIDLFLS IINIPRITTQ LFLESTNKLI EKFISNNEIN QEKITNKKKI HFIFISTIKK
     SLYNISKKNS HIFCDLSYLS QAYVFYKLSQ TQVINLSKFR SVLQYNTTSC FLKTKIKDYF
     KKLGIFHSEL KHKKLQSYRI NQWKNWLRWH YQYDLSQIRW SRLMPKKWRT RVNQSCMAQN
     KNRNLNKWNS YEKDQLIHYK KENDSELYSL SNQKDNFKKC YRYGLLAYKS INYENKSDSF
     FSRLPFQVKK NLEISYNSNT SKHNFVDMPV NLHINNYLRK VNILDIERNL DRKYFDWKII
     HFSLRQKGDI EAWVKIDTNS NPNTKIGINN YQIIDKIEKK GVFYLTTHQN PEKTQKNSKK
     VFFDWMGMNE KIFNRPILNL EFWFFPEFVL LYNVYKIKPW IIPSKFLLFN LNTNENVIQN
     KNQKQNFFLP SNKKIKNRSQ ETKEPPSQRE RGSDIENKGN LSPVFSKHQT DLEKDYVESD
     TKKGQNKKQY KSNTEAELDL FLKRYLLFQL RWNDALNQRM LENIKVYCLL LRLINPTKIT
     ISSIQRREMS LDIMLIQANL PLTDLMKKGV LIIEPIRLSV KHNGQFIMYQ TIGISLVHKS
     KHQTNQRYRE QRYVDKKNFD EFILQPQTQR INTEKTHFDL LVPENILWSR RRRELRIRSF
     FNSLNWNVVD RNSVFCNETN VKNWSQFLGE RKPLYKDKNE LIKFKFFLWP NYRLEDLACM
     NRYWFDTNNG SRFSILRIHM YPRLKIN