TI214_SOLLC
ID TI214_SOLLC Reviewed; 1891 AA.
AC Q2MI42; Q2A7B0; Q2A7C2;
DT 28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT 07-FEB-2006, sequence version 1.
DT 03-AUG-2022, entry version 54.
DE RecName: Full=Protein TIC 214 {ECO:0000250|UniProtKB:P56785};
DE AltName: Full=Translocon at the inner envelope membrane of chloroplasts 214 {ECO:0000250|UniProtKB:P56785};
DE Short=AtTIC214 {ECO:0000250|UniProtKB:P56785};
GN Name=TIC214 {ECO:0000250|UniProtKB:P56785}; Synonyms=ycf1-A;
GN and
GN Name=TIC214 {ECO:0000250|UniProtKB:P56785}; Synonyms=ycf1-B;
OS Solanum lycopersicum (Tomato) (Lycopersicon esculentum).
OG Plastid; Chloroplast.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum;
OC Solanum subgen. Lycopersicon.
OX NCBI_TaxID=4081;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. LA3023;
RX PubMed=16575560; DOI=10.1007/s00122-006-0254-x;
RA Daniell H., Lee S.-B., Grevich J., Saski C., Quesada-Vargas T., Guda C.,
RA Tomkins J., Jansen R.K.;
RT "Complete chloroplast genome sequences of Solanum bulbocastanum, Solanum
RT lycopersicum and comparative analyses with other Solanaceae genomes.";
RL Theor. Appl. Genet. 112:1503-1518(2006).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. IPA-6;
RX PubMed=16830097; DOI=10.1007/s00239-005-0254-5;
RA Kahlau S., Aspinall S., Gray J.C., Bock R.;
RT "Sequence of the tomato chloroplast DNA and evolutionary comparison of
RT solanaceous plastid genomes.";
RL J. Mol. Evol. 63:194-207(2006).
CC -!- FUNCTION: Involved in protein precursor import into chloroplasts. May
CC be part of an intermediate translocation complex acting as a protein-
CC conducting channel at the inner envelope.
CC {ECO:0000250|UniProtKB:P56785}.
CC -!- SUBUNIT: Part of the Tic complex. {ECO:0000250|UniProtKB:P56785}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast inner membrane
CC {ECO:0000250|UniProtKB:P56785}; Multi-pass membrane protein
CC {ECO:0000255}.
CC -!- MISCELLANEOUS: There is a partial copy of the N-terminus (positions 1-
CC 379) of ycf1 in the inverted repeat (CAJ32441).
CC -!- SIMILARITY: Belongs to the TIC214 family. {ECO:0000305}.
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DR EMBL; DQ347959; ABC56359.1; -; Genomic_DNA.
DR EMBL; AM087200; CAJ32453.1; -; Genomic_DNA.
DR EMBL; AM087200; CAJ32441.1; -; Genomic_DNA.
DR RefSeq; AP_004975.1; AC_000188.1.
DR RefSeq; AP_004987.1; AC_000188.1.
DR RefSeq; YP_008563147.1; NC_007898.3.
DR AlphaFoldDB; Q2MI42; -.
DR STRING; 4081.Solyc11g021310.1.1; -.
DR PaxDb; Q2MI42; -.
DR PRIDE; Q2MI42; -.
DR GeneID; 3950474; -.
DR KEGG; sly:3950474; -.
DR eggNOG; ENOG502QSDY; Eukaryota.
DR InParanoid; Q2MI42; -.
DR OrthoDB; 53153at2759; -.
DR Proteomes; UP000004994; Chloroplast.
DR ExpressionAtlas; Q2MI42; baseline and differential.
DR GO; GO:0009706; C:chloroplast inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR InterPro; IPR008896; TIC214.
DR PANTHER; PTHR33163; PTHR33163; 1.
DR Pfam; PF05758; Ycf1; 1.
PE 3: Inferred from homology;
KW Chloroplast; Membrane; Plastid; Plastid inner membrane; Protein transport;
KW Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..1891
FT /note="Protein TIC 214"
FT /id="PRO_0000262630"
FT TRANSMEM 18..38
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 64..84
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 87..107
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 124..144
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 172..192
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 221..241
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 248..300
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 788..807
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1580..1607
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 266..283
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1580..1600
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 374..379
FT /note="QDLFWF -> FLIQKV (in Ref. 2; CAJ32441)"
FT /evidence="ECO:0000305"
FT CONFLICT 1189
FT /note="Q -> K (in Ref. 2; CAJ32453)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 1891 AA; 225281 MW; 73F17C796389B920 CRC64;
MIFQSFLLGN LVSLCMKIIN SVVVVGLYYG FLTTFSIGPS YLFLLRALVM EEGTEKKVSA
TTGFITGQLM MFISIYYAPL HLALGRPHTI TVLALPYLLF HFFWNNHKHF FDYGSTTRNS
MRNLSIQCVF LNNLIFQLFN HFILPSSMLA RLVNIYLFRC NNKILFVTSG FVGWLIGHIL
FMKWLGLVLV WIRQNHSIRS NKYIRSNKYL VLELRNSMAR IFSILLFITC VYYLGRIPSP
ILTKKLKEAS KTEERVESEE ERDVEIETAS EMKGTKQEQE GSTEEDPYPS PSLFSEEGWD
PDKIDETEEI RVNGKDKIKD KFHSHLTETG YNNINTSNSP IYDYQDSYLN NNNTGNLENC
KLQLLDKKNE NQEQDLFWFQ KPLVSLLFDY NRWNRPFRYI KNNRFEQAVR TEMSQYFFDT
CKSDGKQKIS FTYPPSLSTF WKMIKRKIPL LSLQKTLPNE LDTQWVSTNK EKSNNLNKEF
LNRLEILDKE SLSLDILETR TRFCNDDTKK EYVPKMYDPL LNGLYRGTIK KGVSSSIINN
TLLENWEKRV RLNRIHTIFL PNIDYQEFEQ KAYTIDKKPL STEIDEFLTL INELGNEAKS
SLNLKGLSLF SDQEQRRANS EKRTKFVKFV FNALDPNETK SGKKSIGIKE ISKKVPRWSH
KLITELDQQM GEFKDRASMD HQLRSRKAKR VVIFTDNKAT KDAEEEVALI SYSQQSDFRR
GIITGSMRAQ RRKTFISKLF QANVHSPLFV DRITPLRLFS FDISELIKPI LKNWTDKEGE
FKILESREEQ TKREEKKEKD KKEDNKRKEQ ARIAIEEAWD TIPLAQIIRG YMLITQSILR
KYILLPALII AKNIGRMLFL QLPEWSEDLQ EWNREMQIKC TYNGVQLSET EFPKNWLRDG
IQIKILFPFC LKPWHISKLY PSRRELMKKQ KQKDDFCFLT VWGMEAELPF GSPRKRPSFF
EPIFKELEKK IGKFKKKYFL TLKILKGKTK LFRKVSKETT KLFIKSIGFL KKIKKELSKV
NLIVLFRFKE ISESNETKKE KDYLISNQII NESFRQIESG NWPNSSLIET KMKDLTNRTS
TIKNKIERIT KEKKKVTPEI DINPNKTNNI KKFESPKKIF QILKSRNTRV IWKFHYFLKL
FIQRLYINLF LSIINIPRIT TQLFLKSTNK LIEKFISNNE INQEKINNQK KIHFMFISTI
KKSLYNISKK NSHILCDLSY LSQAYVFYKL SQTQVINFSK FRSVLQYNTT SCFLKTKIKD
YFKTLGIFHS ELKHKKLQSY RINQWKNWLR WHYQYDLSQI RWSRLMPKKW RTRVNQSCMA
QNKNRNLNKW NSYEKDQLLH YKKENDSELY SLSNEKDNFK KCYGYGLLAY KSINYENKSD
SFFSRLPFEV QVKKNLEISY NSNTSKHNFV DMPGNLHINN YLRKGNILDR ERNLDRKYFD
WKIIHFSLRQ KGDIEAWVKI DTNSNPNTKI GINNYQIIDK IEKKGVFYLT THQNPEKTQK
NSKKFFFDWM GMNEKIFNRP ILNLEFWFFP EFVLLYNVYK IKPWIIPSKF LLFNLNTNKN
VSQNKNQNFF LPSNKKIKIK NRSQEAKEPP SQRERGSDIE NKGNLSPVFS KHQTDLEKDY
VESDTKKGKN KKQYKSNTEA ELDLFLKRYL LFQLRWNGAL NQRMFENIKV YCLLLRLINP
TKITISSIQR REMSLDIMLI QANLPLTDLM KKGVLIIEPI RLSVKDNGQF IMYQTIGISL
IHKSKHQTNQ RYREQRYVDK KNFDEFILQP QTQRINTEKT HFGLLVPENI LWSRRRRELR
IRSFFNSWNW NVVDRNSVFC NETNVKNWSQ FLGERKPLYK DKNELIKFKF FFWPNYRLED
LACMNRYWFD TNNGSRFSIL RIHMYPRLKI N
