TI214_SOLTU
ID TI214_SOLTU Reviewed; 1887 AA.
AC Q2VEC3;
DT 28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT 10-JAN-2006, sequence version 1.
DT 25-MAY-2022, entry version 48.
DE RecName: Full=Protein TIC 214 {ECO:0000250|UniProtKB:P56785};
DE AltName: Full=Translocon at the inner envelope membrane of chloroplasts 214 {ECO:0000250|UniProtKB:P56785};
DE Short=AtTIC214 {ECO:0000250|UniProtKB:P56785};
GN Name=TIC214 {ECO:0000250|UniProtKB:P56785}; Synonyms=ycf1-A;
GN and
GN Name=TIC214 {ECO:0000250|UniProtKB:P56785}; Synonyms=ycf1-B;
OS Solanum tuberosum (Potato).
OG Plastid; Chloroplast.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum.
OX NCBI_TaxID=4113;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Desiree;
RX PubMed=16835751; DOI=10.1007/s00299-006-0196-4;
RA Chung H.-J., Jung J.D., Park H.-W., Kim J.-H., Cha H.W., Min S.R.,
RA Jeong W.-J., Liu J.R.;
RT "The complete chloroplast genome sequences of Solanum tuberosum and
RT comparative analysis with Solanaceae species identified the presence of a
RT 241-bp deletion in cultivated potato chloroplast DNA sequence.";
RL Plant Cell Rep. 25:1369-1379(2006).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Desiree;
RA Gargano D., Scotti N., Vezzi A., Bilardi A., Valle G., Grillo S., Cardi T.;
RT "Complete chloroplast genome sequences of Solanum tuberosum cultivar
RT Desiree and comparative analyses with other Solanaceae genomes.";
RL Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in protein precursor import into chloroplasts. May
CC be part of an intermediate translocation complex acting as a protein-
CC conducting channel at the inner envelope.
CC {ECO:0000250|UniProtKB:P56785}.
CC -!- SUBUNIT: Part of the Tic complex. {ECO:0000250|UniProtKB:P56785}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast inner membrane
CC {ECO:0000250|UniProtKB:P56785}; Multi-pass membrane protein
CC {ECO:0000255}.
CC -!- SIMILARITY: Belongs to the TIC214 family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; DQ231562; ABB90095.1; -; Genomic_DNA.
DR EMBL; DQ386163; ABD47115.1; -; Genomic_DNA.
DR RefSeq; YP_635697.1; NC_008096.2.
DR AlphaFoldDB; Q2VEC3; -.
DR STRING; 4113.PGSC0003DMT400010726; -.
DR PRIDE; Q2VEC3; -.
DR GeneID; 4099913; -.
DR KEGG; sot:4099913; -.
DR InParanoid; Q2VEC3; -.
DR OrthoDB; 53153at2759; -.
DR Proteomes; UP000011115; Unassembled WGS sequence.
DR GO; GO:0009706; C:chloroplast inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR InterPro; IPR008896; TIC214.
DR PANTHER; PTHR33163; PTHR33163; 1.
DR Pfam; PF05758; Ycf1; 1.
PE 3: Inferred from homology;
KW Chloroplast; Membrane; Plastid; Plastid inner membrane; Protein transport;
KW Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..1887
FT /note="Protein TIC 214"
FT /id="PRO_0000262631"
FT TRANSMEM 18..38
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 64..84
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 87..107
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 124..144
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 172..192
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 221..241
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 248..300
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 785..805
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1569..1603
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 266..283
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1576..1596
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1887 AA; 224964 MW; F35619D3B85B6A2B CRC64;
MIFQSFLLGN LVSLCMKIIN SVVVVGLYYG FLTTFSIGPS YLFLLRALVM EEGTEKKVSA
TTGFITGQLM MFISIYYAPL HLALGRPHTI TVLALPYLLF HFFWNNHKHF FDYGSTTRNS
MRNLSIQCVF LNNLIFQLFN HFILPSSMLA RLVNIYLFRC NNKILFVTSG FVGWLIGHIL
FMKWLGLVLV WIRQNHSIRS NKYIRSNKYL VLELRNSMAR IFSILLFITC VYYLGRIPSP
ILTKKLKEAS KTEERVESEE ERDVEIETAS EMKGTKQEQE GSTEEDPYPS PSLFSEEGWD
PDKIDETEEI RVNGKDKIKD KFHSHLTETG YNNINTSNSP IYDYQDSYLN NNNTGNLENL
KLQLLDKKNE NQDLFWFQKP LVSLLFDYNR WNRPFRYIKN NRFEQAVRTE MSQYFFDTCK
SDGKQRISFT YPPSLSTFWK MIKRKIPLLS LQKTLPNELD TQWVSTNKEK SNNLNKEFLN
RLEILAKESL SMDILETRTR LCNDDTKKEY VPKMYDPLLN GPYRGTIKKG VSSSIINNTL
LENWEKRVRL NRIHTIFLPN MDYQEFEQKA YTIDKKPLST EIDEFLTLIN ELGNEPKSSL
NLKGLSLFSD QEQRRVNSEK RTKFVKFVFN AIDPNETKSG KKSIGIKEIS KKVPRWSHKL
ITELDQQMGE FQDRASIDHQ LRSRKAKRVV IFTDNNATND PEEEVALISY SQQSDFRRGI
IKGSMRAQRR KTFISKLFQA NVHSPLFVDR ITPLRLFSFD ISELIKPIFR NWTGKEGEFK
ILESREEQTK REEKKEKDKK EDNKRKEQAR IAIEEAWDNI PFAQIIRGYM LITQSILRKY
ILLPSLIIAK NLGRMLFLQL PEWSEDLQEW NREMQIKCTY NGVQLSETEF PKDWLRDGIQ
IKILFPFCLK PWHISKLYPS RGELMKKQKQ KDDFCFLTVW GMEAELPFGS PRKRPSFFEP
IFKELEKKIG KLKKKYFLTL KIFKGKTKLF RRVSKETKKW FIKSIGFLKK IKKELSKVNP
IVLFRFKEIS ESNETKKEKD YLISNQIINE SFSQIESGNW PNSSLIETKM KDLTDRTSTI
KNQIERITKD KKKVTPEIDI NPNKTNNIKK LESPKKFFQI LQRRNTRVIW KFHYFLKLFI
QRLYIDLFLS IINIPRITTQ LFLESTNKLI EKFISNNEIN QEKITNKKKI HFIFISTIKK
SLYNISKKNS HIFCDLSYLS QAYVFYKLSQ TQVINLSKFR SVLQYNTTSC FLKTKIKDYF
KTLGIFHSEL KHKKLQSYRI NQWKNWLRWH YQYDLSQIRW SRLMPKKWRT KVNQSCMAKN
KNRNLNKWNS YEKDQLIHYK KENDSELYSL SNQKDNFKKC YRYGLLAYKS INYENKSDSF
FSRLPFQVKK NLEISYNSNT SKHNFVDMPG NLHINNYLRK VNILDIERNL DRKYFDWKII
HFSLRQKGDI EAWVKIDTNS NPNTKIGINN YQIIDKIEKK GVFYLTTHQN PEKTQKNSKK
VFFDWMGMNE KIFNRPILNL EFWFFPEFVL LYNVYKIKPW IIPSKFLLFN LNTNENVIQN
KNQKQNFFLP SNKKIKNRSQ ETKEPPSQRE RGSDIENKGN LSPVFSKHQT DLEKDYVESD
TKKGQNKKQY KSNTEAELDL FLKRYLLFQL RWNDALNKRM LENIKVYCLL LRLINPTKIT
ISSIQRREMS LDIMLIQANL PLTDLMKKGV LIIEPIRLSV KHNGQFIMYQ TIGISLVHKS
KHQTNQRYRE QRYVDKKNFD EFILQPQTQR INTEKTHFDL LVPENILWSR RRRELRIRSF
FNSLNWNVVD RNSVFCNETN VKNWSQFLGE RKPLYKDKKK LIKFKFFLWP NYRLEDLACM
NRYWFDTNNG SRFSILRIHM YPRLKIN
